High-resolution genome-wide mapping of HIF-binding sites by ChIP-seq

Hypoxia-inducible factor (HIF) regulates the major transcriptional cascade central to the response of all mammalian cells to alterations in oxygen tension. Expression arrays indicate that many hundreds of genes are regulated by this pathway, controlling diverse processes that in turn orchestrate bot...

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Veröffentlicht in:	Blood Jg. 117; H. 23; S. e207
Hauptverfasser:	Schödel, Johannes, Oikonomopoulos, Spyros, Ragoussis, Jiannis, Pugh, Christopher W, Ratcliffe, Peter J, Mole, David R
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 09.06.2011
Schlagworte:	Basic Helix-Loop-Helix Transcription Factors - genetics Basic Helix-Loop-Helix Transcription Factors - metabolism Cell Line, Tumor Chromatin Immunoprecipitation - methods Chromosome Mapping Epigenesis, Genetic - physiology Female Genome, Human - physiology Genome-Wide Association Study Humans Oxygen - metabolism Response Elements - physiology
ISSN:	1528-0020, 1528-0020
Online-Zugang:	Weitere Angaben
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