Antiinflammatory effects of reconstituted high-density lipoprotein during human endotoxemia

High-density lipoprotein (HDL) has been found to neutralize LPS activity in vitro and in animals in vivo. We sought to determine the effects of reconstituted HDL (rHDL) on LPS responsiveness in humans in a double-blind, randomized, placebo-controlled, cross-over study. rHDL, given as a 4-h infusion...

Celý popis

Uloženo v:

Podrobná bibliografie
Vydáno v:	The Journal of experimental medicine Ročník 184; číslo 5; s. 1601
Hlavní autoři:	Pajkrt, D, Doran, J E, Koster, F, Lerch, P G, Arnet, B, van der Poll, T, ten Cate, J W, van Deventer, S J
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States 01.11.1996
Témata:	Adult Antigens, CD Apolipoprotein A-I - metabolism Apolipoprotein A-I - therapeutic use Cholesterol - metabolism Cholesterol - therapeutic use Cross-Over Studies Double-Blind Method Endotoxemia - drug therapy Endotoxins - metabolism Granulocytes Humans Inflammation - drug therapy Infusions, Intravenous Interleukin-6 - blood Interleukin-8 - blood Leukocyte Count Lipopolysaccharides - metabolism Lipoproteins, HDL - metabolism Lipoproteins, HDL - therapeutic use Male Monocytes Nausea Pain Phosphatidylcholines - metabolism Phosphatidylcholines - therapeutic use Placebos Shivering Time Factors Tumor Necrosis Factor-alpha - analysis Vomiting
ISSN:	0022-1007
On-line přístup:	Zjistit podrobnosti o přístupu
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!

Buďte první, kdo okomentuje tento záznam!