Prolonged Subculturing of Aspergillus fumigatus on Galleria Extract Agar Results in Altered Virulence and Sensitivity to Antifungal Agents

Aspergillus fumigatus is an environmental saprophyte and opportunistic fungal pathogen of humans. The aim of the work presented here was to examine the effect of serially subculturing A. fumigatus on agar generated from Galleria mellonella larvae in order to characterize the alterations in the pheno...

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Veröffentlicht in:	Cells (Basel, Switzerland) Jg. 12; H. 7; S. 1065
Hauptverfasser:	Curtis, Aaron, Walshe, Kieran, Kavanagh, Kevin
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Switzerland MDPI AG 31.03.2023 MDPI
Schlagworte:	Agar - pharmacology Amphotericin B Animals Antifungal agents Antifungal Agents - pharmacology Aspergillus Aspergillus fumigatus Cystic fibrosis Galleria Genomes Hemocytes Histone H2A Humans Hydrogen peroxide Immune response immunity Immunological tolerance infection Itraconazole Kinases Larva mini-model Moths Opportunist infection Oxidative stress passaging Pathogens Phenotypes Plant Extracts - pharmacology Proteomics Statistical analysis Virulence St Louis Missouri United Kingdom > UK United States > US Aspergillus infection Galleria virulence mini-model passaging immunity
ISSN:	2073-4409, 2073-4409
Online-Zugang:	Volltext
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