Temporal role of Sertoli cell androgen receptor expression in spermatogenic development

Sertoli cell (SC) androgen receptor (AR) activity is vital for spermatogenesis. We created a unique gain-of-function transgenic (Tg) mouse model to determine the temporal role of SCAR expression in testicular development. The SC-specific rat Abpa promoter directed human Tg AR [Tg SC-specific AR (TgS...

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Vydané v:	Molecular endocrinology (Baltimore, Md.) Ročník 27; číslo 1; s. 12
Hlavní autori:	Hazra, Rasmani, Corcoran, Lisa, Robson, Mat, McTavish, Kirsten J, Upton, Dannielle, Handelsman, David J, Allan, Charles M
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 01.01.2013
Predmet:	Animals Female Follicle Stimulating Hormone - blood Gene Expression Gene Expression Regulation, Developmental Humans Male Mice Mice, Transgenic Organ Size Rats Receptors, Androgen - genetics Receptors, Androgen - metabolism Seminiferous Tubules - anatomy & histology Seminiferous Tubules - growth & development Sertoli Cells - metabolism Spermatocytes - metabolism Spermatogenesis Spermatogonia - metabolism Testis - cytology Testis - growth & development Testosterone - blood
ISSN:	1944-9917, 1944-9917
On-line prístup:	Zistit podrobnosti o prístupe
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