Temporal role of Sertoli cell androgen receptor expression in spermatogenic development

Sertoli cell (SC) androgen receptor (AR) activity is vital for spermatogenesis. We created a unique gain-of-function transgenic (Tg) mouse model to determine the temporal role of SCAR expression in testicular development. The SC-specific rat Abpa promoter directed human Tg AR [Tg SC-specific AR (TgS...

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Bibliographic Details
Published in:	Molecular endocrinology (Baltimore, Md.) Vol. 27; no. 1; p. 12
Main Authors:	Hazra, Rasmani, Corcoran, Lisa, Robson, Mat, McTavish, Kirsten J, Upton, Dannielle, Handelsman, David J, Allan, Charles M
Format:	Journal Article
Language:	English
Published:	United States 01.01.2013
Subjects:	Animals Female Follicle Stimulating Hormone - blood Gene Expression Gene Expression Regulation, Developmental Humans Male Mice Mice, Transgenic Organ Size Rats Receptors, Androgen - genetics Receptors, Androgen - metabolism Seminiferous Tubules - anatomy & histology Seminiferous Tubules - growth & development Sertoli Cells - metabolism Spermatocytes - metabolism Spermatogenesis Spermatogonia - metabolism Testis - cytology Testis - growth & development Testosterone - blood
ISSN:	1944-9917, 1944-9917
Online Access:	Get more information
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