Osteopontin impairs host defense during pneumococcal pneumonia

Streptococcus pneumoniae is the most frequently isolated pathogen responsible for community-acquired pneumonia. Osteopontin is involved in inflammation during both innate and adaptive immunity. To determine the role of osteopontin in the host response during pneumococcal pneumonia, osteopontin knock...

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Bibliographic Details
Published in:	The Journal of infectious diseases Vol. 203; no. 12; p. 1850
Main Authors:	van der Windt, Gerritje J W, Hoogendijk, Arie J, Schouten, Marcel, Hommes, Tijmen J, de Vos, Alex F, Florquin, Sandrine, van der Poll, Tom
Format:	Journal Article
Language:	English
Published:	United States 15.06.2011
Subjects:	Animals Cytokines - analysis Interleukins - analysis Kaplan-Meier Estimate Lung - microbiology Lung - physiopathology Mice Mice, Inbred C57BL Mice, Knockout Osteopontin - analysis Osteopontin - genetics Osteopontin - immunology Phagocytosis Pneumonia, Pneumococcal - immunology Pneumonia, Pneumococcal - physiopathology Streptococcus pneumoniae - immunology
ISSN:	1537-6613, 1537-6613
Online Access:	Get more information
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