Trained immunity-related vaccines: innate immune memory and heterologous protection against infections

The innate immune system is able to build memory-like features in response to certain infections or vaccines, resulting in enhanced responsiveness upon (re)challenge with the same or an unrelated pathogen, a phenomenon termed ‘trained immunity’. Compared with antigen-dependent adaptive immune respon...

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Bibliographic Details
Published in:Trends in molecular medicine Vol. 28; no. 6; pp. 497 - 512
Main Authors: Ziogas, Athanasios, Netea, Mihai G.
Format: Journal Article
Language:English
Published: England Elsevier Ltd 01.06.2022
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ISSN:1471-4914, 1471-499X, 1471-499X
Online Access:Get full text
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