NGF and PI3K/Akt signaling participate in the ventral motor neuronal protection of curcumin in sciatic nerve injury rat models

It has been reported that sciatic nerve injury (SNI) leads to degeneration, damage, and apoptosis of motor neurons. Nerve growth factor (NGF) plays a pivotal role in regeneration and reestablishment of neuronal function via activating PI3K/Akt survival signaling pathways. Curcumin owns neuroprotecti...

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Veröffentlicht in:	Biomedicine & pharmacotherapy Jg. 103; S. 1146 - 1153
Hauptverfasser:	Sang, Qiuling, Sun, Daju, Chen, Zonghan, Zhao, Weijia
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	France Elsevier Masson SAS 01.07.2018
Schlagworte:	Curcumin motor neuron injury Nerve growth factor PI3K/Akt motor neuron injury Nerve growth factor Curcumin PI3K/Akt
ISSN:	0753-3322, 1950-6007, 1950-6007
Online-Zugang:	Volltext
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