Hierarchical organization and early hematopoietic specification of the developing HSC lineage in the AGM region

The aorta-gonad-mesonephros region plays an important role in hematopoietic stem cell (HSC) development during mouse embryogenesis. The vascular endothelial cadherin⁺ CD45⁺ (VE-cad⁺CD45⁺) population contains the major type of immature pre-HSCs capable of developing into long-term repopulating defini...

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Veröffentlicht in:	The Journal of experimental medicine Jg. 208; H. 6; S. 1305
Hauptverfasser:	Rybtsov, Stanislav, Sobiesiak, Malgorzata, Taoudi, Samir, Souilhol, Céline, Senserrich, Jordi, Liakhovitskaia, Anna, Ivanovs, Andrejs, Frampton, Jon, Zhao, Suling, Medvinsky, Alexander
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 06.06.2011
Schlagworte:	Animals Aorta - metabolism Cadherins - metabolism Cell Lineage Cell Separation Endothelium, Vascular - cytology Flow Cytometry Green Fluorescent Proteins - metabolism Hematopoietic Stem Cells - cytology Leukocyte Common Antigens - biosynthesis Mice Models, Genetic Phenotype Platelet Membrane Glycoprotein IIb - biosynthesis Transgenes
ISSN:	1540-9538, 1540-9538
Online-Zugang:	Weitere Angaben
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