Many stimuli pull the necrotic trigger, an overview

The lab of Jürg Tschopp was the first to report on the crucial role of receptor-interacting protein kinase 1 (RIPK1) in caspase-independent cell death. Because of this pioneer finding, regulated necrosis and in particular RIPK1/RIPK3 kinase-mediated necrosis, referred to as necroptosis, has become a...

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Bibliographic Details
Published in:	Cell death and differentiation Vol. 19; no. 1; pp. 75 - 86
Main Authors:	Vanlangenakker, N, Vanden Berghe, T, Vandenabeele, P
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 01.01.2012 Nature Publishing Group
Subjects:	Animals Apoptosis Apoptosis - genetics Biochemistry Biomedical and Life Sciences Biomedical research Cell Biology Cell Cycle Analysis Cell death Communicable Diseases - metabolism Communicable Diseases - microbiology Communicable Diseases - virology Cytokines Humans Ischemia Kinases Life Sciences Ligands Mice Necrosis - genetics Necrosis - metabolism Pathogens Proteins Receptor-Interacting Protein Serine-Threonine Kinases - genetics Receptor-Interacting Protein Serine-Threonine Kinases - metabolism Receptors, Tumor Necrosis Factor - genetics Receptors, Tumor Necrosis Factor - metabolism Reperfusion Injury - metabolism Reperfusion Injury - pathology Review Stem Cells Stress, Physiological - genetics Tumor necrosis factor-TNF Tumor Necrosis Factors - genetics Tumor Necrosis Factors - metabolism Viral infections West Nile virus Belgium cytokines pathogens necrosis necroptosis
ISSN:	1350-9047, 1476-5403, 1476-5403
Online Access:	Get full text
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