The Colon-26 Carcinoma Tumor-bearing Mouse as a Model for the Study of Cancer Cachexia

Cancer cachexia is the progressive loss of skeletal muscle mass and adipose tissue, negative nitrogen balance, anorexia, fatigue, inflammation, and activation of lipolysis and proteolysis systems. Cancer patients with cachexia benefit less from anti-neoplastic therapies and show increased mortality...

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Bibliographic Details
Published in:	Journal of visualized experiments no. 117
Main Authors:	Bonetto, Andrea, Rupert, Joseph E., Barreto, Rafael, Zimmers, Teresa A.
Format:	Journal Article
Language:	English
Published:	United States MyJove Corporation 30.11.2016
Subjects:	adipose tissue animal models Animals anorexia cachexia Cachexia - etiology Cancer Research carcinoma Cell Line, Tumor Colonic Neoplasms Disease Models, Animal freezing heart Humans inflammation Interleukin-6 lipolysis liver Mice Muscle, Skeletal muscles Muscular Atrophy - etiology nitrogen balance patients proteolysis Reproducibility of Results skeletal muscle spleen ubiquitin-protein ligase
ISSN:	1940-087X, 1940-087X
Online Access:	Get full text
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