Small Nucleolar Noncoding RNA SNORA23, Up-Regulated in Human Pancreatic Ductal Adenocarcinoma, Regulates Expression of Spectrin Repeat-Containing Nuclear Envelope 2 to Promote Growth and Metastasis of Xenograft Tumors in Mice

Small nucleolar noncoding RNAs (snoRNAs) regulate function of ribosomes, and specific snoRNAs are dysregulated in some cancer cells. We investigated dysregulation of snoRNAs in pancreatic ductal adenocarcinoma (PDAC) cells. We investigated snoRNA expression in PDAC cell lines by complementary DNA mi...

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Vydáno v:	Gastroenterology (New York, N.Y. 1943) Ročník 153; číslo 1; s. 292
Hlavní autoři:	Cui, Lin, Nakano, Kenji, Obchoei, Sumalee, Setoguchi, Kiyoko, Matsumoto, Masaki, Yamamoto, Tsuyoshi, Obika, Satoshi, Shimada, Kazuaki, Hiraoka, Nobuyoshi
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States 01.07.2017
Témata:	Animals Carcinoma, Pancreatic Ductal - chemistry Carcinoma, Pancreatic Ductal - genetics Carcinoma, Pancreatic Ductal - secondary Cell Line, Tumor Cell Nucleolus - metabolism Cell Proliferation - genetics DNA, Complementary - analysis Female Gene Expression Gene Expression Regulation, Neoplastic Gene Knockdown Techniques Humans Karyopherins - genetics Liver Neoplasms - secondary Male Mice Microfilament Proteins - genetics Microfilament Proteins - metabolism Middle Aged Neoplasm Invasiveness - genetics Neoplasm Transplantation Nerve Tissue Proteins - genetics Nerve Tissue Proteins - metabolism Nuclear Proteins - genetics Nuclear Proteins - metabolism Oligonucleotide Array Sequence Analysis Oligonucleotides, Antisense - therapeutic use Pancreas - chemistry Pancreatic Neoplasms - chemistry Pancreatic Neoplasms - genetics Pancreatic Neoplasms - pathology Proteome Receptors, Cytoplasmic and Nuclear - genetics RNA, Messenger - metabolism RNA, Small Nucleolar - analysis RNA, Small Nucleolar - antagonists & inhibitors RNA, Small Nucleolar - genetics RNA, Small Nucleolar - metabolism Spheroids, Cellular Survival Rate Transfection Up-Regulation Liver Metastasis Non-Coding RNA Pancreatic Cancer Oncogene
ISSN:	1528-0012, 1528-0012
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