Short- and long-term reproducibility of time and frequency domain heart rate variability measurements in normal subjects
To obtain data relating to the reproducibility of the time and frequency domain measurements obtained from 10-min ECG recordings. Eighteen normal volunteers underwent evaluations of time and frequency domain heart rate variability 2 weeks and 7 months after baseline analysis. The time domain paramet...
Saved in:
| Published in: | Cardiovascular research Vol. 32; no. 2; p. 226 |
|---|---|
| Main Authors: | , , , , , , , , |
| Format: | Journal Article |
| Language: | English |
| Published: |
England
01.08.1996
|
| Subjects: | |
| ISSN: | 0008-6363 |
| Online Access: | Get more information |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Abstract | To obtain data relating to the reproducibility of the time and frequency domain measurements obtained from 10-min ECG recordings.
Eighteen normal volunteers underwent evaluations of time and frequency domain heart rate variability 2 weeks and 7 months after baseline analysis. The time domain parameters were mean NN, the standard deviation of NN intervals, the percentage of successive NN intervals > 50 ms and the root mean square successive difference of NN intervals. The frequency domain evaluations (total power, low frequency, and high frequency) were made by means of both the Fast Fourier Transform algorithm (FFT) and the autoregressive method (AR) from 10-min ECG recordings made under three different conditions: rest, controlled respiration, and after a passive head-up tilt test. Reproducibility was evaluated by means of the interclass correlation coefficient (ICC), comparing baseline values with the results obtained at the second week and the seventh month. Time domain evaluation were also made from 10-min ECG.
All of the time domain measurements had an ICC > or = 0.75, except for the standard deviation of NN intervals, which had an ICC of 0.57. The frequency domain parameters obtained by means of either FFT or AR showed similar reproducibility. Low frequency was reproducible under all three conditions, total power only at rest, and high frequency only during controlled respiration.
The reproducibility of frequency domain parameters depends on the analysed condition. These results are of primary importance when the effects of drugs or other interventions on heart rate variability are under investigation. |
|---|---|
| AbstractList | To obtain data relating to the reproducibility of the time and frequency domain measurements obtained from 10-min ECG recordings.
Eighteen normal volunteers underwent evaluations of time and frequency domain heart rate variability 2 weeks and 7 months after baseline analysis. The time domain parameters were mean NN, the standard deviation of NN intervals, the percentage of successive NN intervals > 50 ms and the root mean square successive difference of NN intervals. The frequency domain evaluations (total power, low frequency, and high frequency) were made by means of both the Fast Fourier Transform algorithm (FFT) and the autoregressive method (AR) from 10-min ECG recordings made under three different conditions: rest, controlled respiration, and after a passive head-up tilt test. Reproducibility was evaluated by means of the interclass correlation coefficient (ICC), comparing baseline values with the results obtained at the second week and the seventh month. Time domain evaluation were also made from 10-min ECG.
All of the time domain measurements had an ICC > or = 0.75, except for the standard deviation of NN intervals, which had an ICC of 0.57. The frequency domain parameters obtained by means of either FFT or AR showed similar reproducibility. Low frequency was reproducible under all three conditions, total power only at rest, and high frequency only during controlled respiration.
The reproducibility of frequency domain parameters depends on the analysed condition. These results are of primary importance when the effects of drugs or other interventions on heart rate variability are under investigation. To obtain data relating to the reproducibility of the time and frequency domain measurements obtained from 10-min ECG recordings.OBJECTIVETo obtain data relating to the reproducibility of the time and frequency domain measurements obtained from 10-min ECG recordings.Eighteen normal volunteers underwent evaluations of time and frequency domain heart rate variability 2 weeks and 7 months after baseline analysis. The time domain parameters were mean NN, the standard deviation of NN intervals, the percentage of successive NN intervals > 50 ms and the root mean square successive difference of NN intervals. The frequency domain evaluations (total power, low frequency, and high frequency) were made by means of both the Fast Fourier Transform algorithm (FFT) and the autoregressive method (AR) from 10-min ECG recordings made under three different conditions: rest, controlled respiration, and after a passive head-up tilt test. Reproducibility was evaluated by means of the interclass correlation coefficient (ICC), comparing baseline values with the results obtained at the second week and the seventh month. Time domain evaluation were also made from 10-min ECG.METHODSEighteen normal volunteers underwent evaluations of time and frequency domain heart rate variability 2 weeks and 7 months after baseline analysis. The time domain parameters were mean NN, the standard deviation of NN intervals, the percentage of successive NN intervals > 50 ms and the root mean square successive difference of NN intervals. The frequency domain evaluations (total power, low frequency, and high frequency) were made by means of both the Fast Fourier Transform algorithm (FFT) and the autoregressive method (AR) from 10-min ECG recordings made under three different conditions: rest, controlled respiration, and after a passive head-up tilt test. Reproducibility was evaluated by means of the interclass correlation coefficient (ICC), comparing baseline values with the results obtained at the second week and the seventh month. Time domain evaluation were also made from 10-min ECG.All of the time domain measurements had an ICC > or = 0.75, except for the standard deviation of NN intervals, which had an ICC of 0.57. The frequency domain parameters obtained by means of either FFT or AR showed similar reproducibility. Low frequency was reproducible under all three conditions, total power only at rest, and high frequency only during controlled respiration.RESULTSAll of the time domain measurements had an ICC > or = 0.75, except for the standard deviation of NN intervals, which had an ICC of 0.57. The frequency domain parameters obtained by means of either FFT or AR showed similar reproducibility. Low frequency was reproducible under all three conditions, total power only at rest, and high frequency only during controlled respiration.The reproducibility of frequency domain parameters depends on the analysed condition. These results are of primary importance when the effects of drugs or other interventions on heart rate variability are under investigation.CONCLUSIONThe reproducibility of frequency domain parameters depends on the analysed condition. These results are of primary importance when the effects of drugs or other interventions on heart rate variability are under investigation. |
| Author | Passantino, A Mastropasqua, F Di Maggio, M Di Biase, M Massari, F Rizzon, P Colombo, R Forleo, C Pitzalis, M V |
| Author_xml | – sequence: 1 givenname: M V surname: Pitzalis fullname: Pitzalis, M V organization: Institute of Cardiology, University of Bari, Italy – sequence: 2 givenname: F surname: Mastropasqua fullname: Mastropasqua, F – sequence: 3 givenname: F surname: Massari fullname: Massari, F – sequence: 4 givenname: C surname: Forleo fullname: Forleo, C – sequence: 5 givenname: M surname: Di Maggio fullname: Di Maggio, M – sequence: 6 givenname: A surname: Passantino fullname: Passantino, A – sequence: 7 givenname: R surname: Colombo fullname: Colombo, R – sequence: 8 givenname: M surname: Di Biase fullname: Di Biase, M – sequence: 9 givenname: P surname: Rizzon fullname: Rizzon, P |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/8796108$$D View this record in MEDLINE/PubMed |
| BookMark | eNo9kM1OwzAQhH0oKm3hDUDyCcEhYCdx4hxRxZ9UiQNwjmxnTV3FdrEdRN-eABGn1ay-Hc3sEs2cd4DQGSXXlNDqhhDCs6qoisumuvoRVVbP0OJ_fYyWMe5GyVhdztGc101FCV-gr5etDynDwnW49-49SxAsDrAPvhuUkaY36YC9xslY-KV0gI8BnDrgzlthHN6CCAkHkQB_imDEdGNBxCGABZciHjHngxU9joPcgUrxBB1p0Uc4neYKvd3fva4fs83zw9P6dpOpktOU8UKzWpCca62IhE4WROuqY4rVUjUl1BVTqi4FIyVvOCtyKnIouJRjc8p1ma_QxZ_v2GjMHVNrTVTQ98KBH2Jb84IyzsgInk_gIC107T4YK8KhnV6VfwM_i24Y |
| CitedBy_id | crossref_primary_10_1089_dia_2010_0070 crossref_primary_10_2337_diacare_24_6_1108 crossref_primary_10_1111_psyp_14604 crossref_primary_10_1016_j_jneuroim_2013_04_011 crossref_primary_10_3390_e22111302 crossref_primary_10_7554_eLife_62324 crossref_primary_10_1016_j_biopsycho_2011_03_002 crossref_primary_10_3390_jcm8050655 crossref_primary_10_1027_0269_8803_a000200 crossref_primary_10_1007_s10286_005_0293_4 crossref_primary_10_52082_jssm_2022_260 crossref_primary_10_1016_j_ijcard_2004_12_018 crossref_primary_10_1007_s10441_012_9154_4 crossref_primary_10_1038_s41598_023_45184_2 crossref_primary_10_1097_EDE_0000000000000455 crossref_primary_10_1111_j_1540_8159_1998_tb00099_x crossref_primary_10_1016_j_ijcard_2004_09_013 crossref_primary_10_1109_ACCESS_2019_2895998 crossref_primary_10_1097_00126097_200502000_00005 crossref_primary_10_1080_1750984X_2025_2541350 crossref_primary_10_1088_0967_3334_32_3_001 crossref_primary_10_1046_j_1365_2281_1999_00165_x crossref_primary_10_1016_j_autneu_2010_03_019 crossref_primary_10_2114_jpa2_26_173 crossref_primary_10_1007_s11896_014_9142_5 crossref_primary_10_1007_BF03324616 crossref_primary_10_3389_fphys_2021_675899 crossref_primary_10_1007_s00420_008_0391_4 crossref_primary_10_1016_j_ijpsycho_2016_04_008 crossref_primary_10_1097_MBP_0000000000000241 crossref_primary_10_1080_02640414_2012_721931 crossref_primary_10_1136_bjsm_37_6_550 crossref_primary_10_1177_2333794X15589560 crossref_primary_10_1007_s00421_012_2472_z crossref_primary_10_1007_s00228_008_0505_7 crossref_primary_10_1371_journal_pone_0151464 crossref_primary_10_1177_0091270008325927 crossref_primary_10_1016_j_clinph_2011_02_032 crossref_primary_10_1016_j_jelectrocard_2004_04_004 crossref_primary_10_1016_S0002_9149_00_01217_0 crossref_primary_10_1111_cpf_12321 crossref_primary_10_1378_chest_114_1_185 crossref_primary_10_1111_j_1469_8986_2006_00490_x crossref_primary_10_1111_j_1540_8159_1998_tb00182_x crossref_primary_10_1007_s00421_014_3066_8 crossref_primary_10_1080_13548506_2014_987148 crossref_primary_10_1155_2012_931943 crossref_primary_10_2114_jpa2_28_225 crossref_primary_10_1111_j_1542_474X_2005_00579_x crossref_primary_10_1002_hsr2_984 crossref_primary_10_1016_S0167_5273_98_00024_2 crossref_primary_10_1097_00005768_200011000_00012 crossref_primary_10_1111_j_1475_097X_2012_01125_x crossref_primary_10_1111_cpf_12475 crossref_primary_10_1016_S0188_4409_00_00255_1 crossref_primary_10_1007_s11517_006_0097_2 crossref_primary_10_1111_j_1469_8986_2011_01341_x crossref_primary_10_1007_s00424_021_02632_0 crossref_primary_10_1007_s10286_005_0302_7 crossref_primary_10_1016_j_autneu_2021_102896 crossref_primary_10_1088_0967_3334_21_2_310 crossref_primary_10_1007_s10877_009_9210_z crossref_primary_10_1186_1475_925X_10_96 crossref_primary_10_1109_JTEHM_2022_3175361 crossref_primary_10_1177_09727531241310034 crossref_primary_10_1002_dev_21088 crossref_primary_10_1088_0967_3334_33_7_1123 crossref_primary_10_1161_01_CIR_96_12_4326 crossref_primary_10_1088_0967_3334_22_4_302 crossref_primary_10_1089_jcr_2016_0028 crossref_primary_10_1111_cpf_12190 crossref_primary_10_1111_1469_8986_00039 crossref_primary_10_1249_MSS_0b013e318184a4b1 crossref_primary_10_1016_j_ijpsycho_2012_01_011 crossref_primary_10_1016_j_ijpsycho_2013_05_017 crossref_primary_10_1016_j_arcmed_2006_07_009 crossref_primary_10_1016_S0188_4409_03_00023_7 crossref_primary_10_3109_00365510902946984 crossref_primary_10_1097_00004872_200101000_00019 crossref_primary_10_1186_1751_0759_2_12 crossref_primary_10_1016_j_biopsycho_2012_09_002 crossref_primary_10_1016_j_ijpsycho_2014_04_005 crossref_primary_10_1016_j_ahj_2004_10_031 crossref_primary_10_1027_0269_8803_a000187 crossref_primary_10_1038_s41598_025_89892_3 crossref_primary_10_1111_j_1475_097X_2007_00736_x crossref_primary_10_1016_j_sleep_2014_10_012 crossref_primary_10_1088_1361_6579_adae51 crossref_primary_10_1088_0967_3334_31_3_006 crossref_primary_10_3390_jcm12093118 crossref_primary_10_1016_j_jvn_2013_12_001 crossref_primary_10_1186_1880_6805_31_9 crossref_primary_10_1371_journal_pone_0072664 crossref_primary_10_1016_S1566_0702_01_00266_1 crossref_primary_10_1016_j_biopsycho_2006_04_008 crossref_primary_10_1016_S0002_8703_98_70178_4 crossref_primary_10_1016_j_biopsycho_2020_107905 |
| ContentType | Journal Article |
| DBID | CGR CUY CVF ECM EIF NPM 7X8 |
| DOI | 10.1016/0008-6363(96)00086-7 |
| DatabaseName | Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed MEDLINE - Academic |
| DatabaseTitle | MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) MEDLINE - Academic |
| DatabaseTitleList | MEDLINE MEDLINE - Academic |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: 7X8 name: MEDLINE - Academic url: https://search.proquest.com/medline sourceTypes: Aggregation Database |
| DeliveryMethod | no_fulltext_linktorsrc |
| Discipline | Medicine |
| ExternalDocumentID | 8796108 |
| Genre | Journal Article |
| GroupedDBID | --- --K -E4 .2P .55 .GJ .I3 .ZR 08P 0R~ 18M 1B1 1TH 29B 2WC 3O- 4.4 48X 53G 5GY 5RE 5VS 5WD 6.Y 6J9 70D AABZA AACZT AAGQS AAJKP AAJQQ AAMVS AAOGV AAPGJ AAPNW AAPQZ AAPXW AARHZ AAUAY AAUQX AAVAP AAWDT ABDFA ABEJV ABEUO ABGNP ABHFT ABIXL ABJNI ABKDP ABLJU ABNGD ABNHQ ABNKS ABOCM ABPTD ABQLI ABQNK ABQTQ ABSAR ABSMQ ABVGC ABWST ABXVV ABZBJ ACFRR ACGFO ACGFS ACPQN ACUFI ACUTJ ACUTO ACYHN ACZBC ADBBV ADEYI ADEZT ADGZP ADHKW ADHZD ADIPN ADJQC ADOCK ADQBN ADRIX ADRTK ADVEK ADYVW ADZXQ AEGPL AEGXH AEJOX AEJTW AEKPW AEKSI AEMDU AENEX AENZO AEPUE AETBJ AEWNT AFFNX AFFQV AFFZL AFIYH AFOFC AFSHK AFXAL AFXEN AFYAG AGINJ AGKEF AGKRT AGMDO AGQXC AGSYK AGUTN AHMMS AHXPO AI. AIAGR AIJHB AJEEA ALMA_UNASSIGNED_HOLDINGS ALUQC APIBT APJGH APWMN AQDSO AQKUS ASPBG ATGXG ATTQO AVWKF AXUDD AZFZN BAWUL BAYMD BCRHZ BEYMZ BHONS BTRTY BVRKM BZKNY C45 CDBKE CGR CS3 CUY CVF CZ4 DAKXR DIK DILTD DU5 D~K E3Z EBD EBS ECM EE~ EIF EIHJH EJD EMOBN ENERS F5P F9B FECEO FEDTE FLUFQ FOEOM FOTVD FQBLK GAUVT GJXCC GX1 H13 H5~ HAR HVGLF HW0 HZ~ IHE IOX J21 J5H JXSIZ KAQDR KBUDW KOP KSI KSN L7B LMP M-Z M41 M49 MBLQV MHKGH MJL N4W N9A NGC NOMLY NOYVH NPM NQ- NU- NVLIB O0~ O9- OAUYM OAWHX OCZFY ODMLO OJQWA OJZSN OK1 OOVWX OPAEJ OVD OWPYF O~Y P2P PAFKI PB- PEELM Q1. Q5Y QBD R44 RD5 RIG ROL ROX ROZ RPZ RUSNO RW1 RXO SEL SV3 TCURE TEORI TJX TMA VH1 W8F WH7 X7H X7M XPP YAYTL YKOAZ YXANX ZGI ZXP ~91 7X8 ABPQP ACUKT ADNBA AEMQT AGQPQ AJBYB AJNCP ALXQX |
| ID | FETCH-LOGICAL-c481t-83f57a028ffc0bedb30ff6d5c57bc94e765cc74a5048985321a2e38bb00818f42 |
| IEDL.DBID | 7X8 |
| ISICitedReferencesCount | 123 |
| ISICitedReferencesURI | http://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=Summon&SrcAuth=ProQuest&DestLinkType=CitingArticles&DestApp=WOS_CPL&KeyUT=10.1016/0008-6363(96)00086-7&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D |
| ISSN | 0008-6363 |
| IngestDate | Wed Oct 01 13:57:00 EDT 2025 Wed Feb 19 02:32:42 EST 2025 |
| IsDoiOpenAccess | false |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 2 |
| Language | English |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c481t-83f57a028ffc0bedb30ff6d5c57bc94e765cc74a5048985321a2e38bb00818f42 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
| OpenAccessLink | https://academic.oup.com/cardiovascres/article-pdf/32/2/226/1006599/32-2-226.pdf |
| PMID | 8796108 |
| PQID | 78315850 |
| PQPubID | 23479 |
| ParticipantIDs | proquest_miscellaneous_78315850 pubmed_primary_8796108 |
| PublicationCentury | 1900 |
| PublicationDate | 1996-08-01 |
| PublicationDateYYYYMMDD | 1996-08-01 |
| PublicationDate_xml | – month: 08 year: 1996 text: 1996-08-01 day: 01 |
| PublicationDecade | 1990 |
| PublicationPlace | England |
| PublicationPlace_xml | – name: England |
| PublicationTitle | Cardiovascular research |
| PublicationTitleAlternate | Cardiovasc Res |
| PublicationYear | 1996 |
| SSID | ssj0005574 |
| Score | 1.8646009 |
| Snippet | To obtain data relating to the reproducibility of the time and frequency domain measurements obtained from 10-min ECG recordings.
Eighteen normal volunteers... To obtain data relating to the reproducibility of the time and frequency domain measurements obtained from 10-min ECG recordings.OBJECTIVETo obtain data... |
| SourceID | proquest pubmed |
| SourceType | Aggregation Database Index Database |
| StartPage | 226 |
| SubjectTerms | Adult Electrocardiography Female Heart Rate - physiology Humans Male Reproducibility of Results Signal Processing, Computer-Assisted Tilt-Table Test |
| Title | Short- and long-term reproducibility of time and frequency domain heart rate variability measurements in normal subjects |
| URI | https://www.ncbi.nlm.nih.gov/pubmed/8796108 https://www.proquest.com/docview/78315850 |
| Volume | 32 |
| WOSCitedRecordID | wos10.1016/0008-6363(96)00086-7&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D |
| hasFullText | |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1JSwMxFA51Qby4F-uagwc9BGcmk2VAEBHFgy0FF3orSSZRQWe00xb7732ZRU_iwcscQgIh8_LyvZcv30PoKEwMhFwBI4pzRWILO11aGhClFYANayJVkmgeb0WvJweDpN9CZ81bGE-rbHxi6ajT3Pgc-amQNARoG5y_fxBfM8rfrdYFNObQAgUg4wldYvCjFc5YrcEcSMIpp83DuZCffrcdJ_ykhPVE_A4xy6PmevV_k1xDKzXExBeVTayjls020FK3vkTfRJ93z4C5CVZZil_z7Il474y9uqUXf63YsjOcO-zrzpe93KgiXM9wmr-plwz7Mthj7FUm8BSCbVWPeftJOBYYumUeEL_iYqJ9tqfYQg_XV_eXN6QuwEBMLMMxkdQxoQCBOGcCbVNNA-d4ygwT2iSxFZwZI2LFwA0kcO5HoYoslVqXQnkujtpoPsszu42w5amEzhDxGWiXUrtUyzAWTgWJiqjqoMNmRYdg4P7WQmU2nxTDZk07qF39lOF7pcMxlCIB8Cd3_hy6i5YrsrXn7e2hBQc72-6jRTMdvxSjg9Js4Nvrd78AiejOOQ |
| linkProvider | ProQuest |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Short-+and+long-term+reproducibility+of+time+and+frequency+domain+heart+rate+variability+measurements+in+normal+subjects&rft.jtitle=Cardiovascular+research&rft.au=Pitzalis%2C+M+V&rft.au=Mastropasqua%2C+F&rft.au=Massari%2C+F&rft.au=Forleo%2C+C&rft.date=1996-08-01&rft.issn=0008-6363&rft.volume=32&rft.issue=2&rft.spage=226&rft_id=info:doi/10.1016%2F0008-6363%2896%2900086-7&rft_id=info%3Apmid%2F8796108&rft_id=info%3Apmid%2F8796108&rft.externalDocID=8796108 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0008-6363&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0008-6363&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0008-6363&client=summon |