Kernelizations for the hybridization number problem on multiple nonbinary trees
Given a finite set X, a collection T of rooted phylogenetic trees on X and an integer k, the Hybridization Number problem asks if there exists a phylogenetic network on X that displays all trees from T and has reticulation number at most k. We show two kernelization algorithms for Hybridization Numb...
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| Vydané v: | Journal of computer and system sciences Ročník 82; číslo 6; s. 1075 - 1089 |
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01.09.2016
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| Abstract | Given a finite set X, a collection T of rooted phylogenetic trees on X and an integer k, the Hybridization Number problem asks if there exists a phylogenetic network on X that displays all trees from T and has reticulation number at most k. We show two kernelization algorithms for Hybridization Number, with kernel sizes 4k(5k)t and 20k2(Δ+−1) respectively, with t the number of input trees and Δ+ their maximum outdegree. Experiments on simulated data demonstrate the practical relevance of our kernelization algorithms. In addition, we present an nf(k)t-time algorithm, with n=|X| and f some computable function of k.
•We study constructing a network displaying a given collection of phylogenetic trees.•Our kernelization techniques work for inputs consisting of multiple binary trees.•Previous results were restricted to two trees and/or binary trees.•A unified and simplified approach for dealing with common chains of nonbinary trees.•Polynomial-time solvability with fixed number of reticulations. |
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| AbstractList | Given a finite set X, a collection T of rooted phylogenetic trees on X and an integer k, the Hybridization Number problem asks if there exists a phylogenetic network on X that displays all trees from T and has reticulation number at most k. We show two kernelization algorithms for Hybridization Number, with kernel sizes 4k(5k)t and 20k2(Δ+−1) respectively, with t the number of input trees and Δ+ their maximum outdegree. Experiments on simulated data demonstrate the practical relevance of our kernelization algorithms. In addition, we present an nf(k)t-time algorithm, with n=|X| and f some computable function of k.
•We study constructing a network displaying a given collection of phylogenetic trees.•Our kernelization techniques work for inputs consisting of multiple binary trees.•Previous results were restricted to two trees and/or binary trees.•A unified and simplified approach for dealing with common chains of nonbinary trees.•Polynomial-time solvability with fixed number of reticulations. Given a finite set X , a collection TT of rooted phylogenetic trees on X and an integer k, the Hybridization Number problem asks if there exists a phylogenetic network on X that displays all trees from TT and has reticulation number at most k. We show two kernelization algorithms for Hybridization Number, with kernel sizes 4k(5k) super(t)4k(5k)t and 20k super(2)( Delta super(+)-1)20k2( Delta +-1 ) respectively, with t the number of input trees and Delta super(+) Delta + their maximum outdegree. Experiments on simulated data demonstrate the practical relevance of our kernelization algorithms. In addition, we present an n super(f(k))tnf(k)t-time algorithm, with n=|X|n=|X| and f some computable function of k. Given a finite set X, a collection T of rooted phylogenetic trees on X and an integer k, the Hybridization Number problem asks if there exists a phylogenetic network on X that displays all trees from T and has reticulation number at most k. We show two kernelization algorithms for Hybridization Number, with kernel sizes 4k(5k) t and 20k 2 (∆ + − 1) respectively, with t the number of input trees and ∆ + their maximum outdegree. Experiments on simulated data demonstrate the practical relevance of our kernelization algorithms. In addition, we present an n f (k) t-time algorithm, with n = |X| and f some computable function of k. |
| Author | van Iersel, Leo Kelk, Steven Scornavacca, Celine |
| Author_xml | – sequence: 1 givenname: Leo surname: van Iersel fullname: van Iersel, Leo email: l.j.j.v.iersel@gmail.com organization: Delft Institute of Applied Mathematics, Delft University of Technology, P.O. Box 5, 2600 AA Delft, The Netherlands – sequence: 2 givenname: Steven surname: Kelk fullname: Kelk, Steven email: steven.kelk@maastrichtuniversity.nl organization: Department of Knowledge Engineering (DKE), Maastricht University, P.O. Box 616, 6200 MD Maastricht, The Netherlands – sequence: 3 givenname: Celine surname: Scornavacca fullname: Scornavacca, Celine email: celine.scornavacca@univ-montp2.fr organization: ISEM, Université de Montpellier, CNRS, IRD, EPHE, Place Eugène Bataillon, 34095, Montpellier, France |
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| Cites_doi | 10.1016/j.ipl.2013.02.010 10.1016/j.tig.2013.05.007 10.1137/110845045 10.1109/TCBB.2012.134 10.1109/TCBB.2011.137 10.1016/0025-5564(90)90123-G 10.1093/bioinformatics/btr618 10.1137/S0097539704446529 10.1137/120864350 10.1007/978-3-540-39763-2_22 10.1109/tcbb.2007.1019 10.1016/j.jcss.2009.04.001 10.1007/s00285-005-0315-9 10.1089/cmb.2013.0072 10.1007/s00453-012-9708-5 10.1137/120903567 10.1089/cmb.2012.0240 10.1093/sysbio/46.3.523 10.1093/bioinformatics/btq198 10.1353/lan.2005.0078 10.1016/j.dam.2006.08.008 10.1109/TCBB.2008.86 10.1007/s00026-015-0260-2 |
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| Keywords | Hybridization number Phylogenetic network Fixed-parameter tractability Phylogenetic tree Kernelization phylogenetic network phylogenetic tree hybridization number kernelization |
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| Snippet | Given a finite set X, a collection T of rooted phylogenetic trees on X and an integer k, the Hybridization Number problem asks if there exists a phylogenetic... Given a finite set X , a collection TT of rooted phylogenetic trees on X and an integer k, the Hybridization Number problem asks if there exists a phylogenetic... |
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| SubjectTerms | Algorithms Bioinformatics Collection Computer Science Computer simulation Displays Fixed-parameter tractability Hybridization number Kernelization Kernels Mathematical analysis Mathematical models Phylogenetic network Phylogenetic tree Trees |
| Title | Kernelizations for the hybridization number problem on multiple nonbinary trees |
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