Computational methods for Gene Regulatory Networks reconstruction and analysis: A review

•The inference of Gene Regulatory Networks enables the integrative analysis of biological systems.•Novel computational approaches have been developed for network reconstruction and evaluation.•Gene Network validation still remains a challenging step of the process.•This review presents a comprehensi...

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Bibliographic Details

Published in:	Artificial intelligence in medicine Vol. 95; pp. 133 - 145
Main Authors:	Delgado, Fernando M., Gómez-Vela, Francisco
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier B.V 01.04.2019
Subjects:	Computational Biology - methods Gene Network Gene Network inference Gene Regulatory Network Gene Regulatory Networks Humans Networks validation Systems biology Networks validation Gene Network inference Gene Regulatory Network Systems biology Gene Network
ISSN:	0933-3657, 1873-2860, 1873-2860
Online Access:	Get full text
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