Meta-analysis of immune-related adverse events in phase 3 clinical trials assessing immune checkpoint inhibitors for lung cancer

•This meta-analysis of immune-related adverse events (irAEs) of checkpoint inhibitors (ICIs) in lung cancer showed that immunotherapy is associated with a lower risk of irAEs compared to immuno-chemotherapy, especially when analysis is restricted to monoimmunotherapy.•Drug discontinuation due to irA...

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Veröffentlicht in:	Critical reviews in oncology/hematology Jg. 162; S. 103351
Hauptverfasser:	Berti, Alvise, Bortolotti, Roberto, Dipasquale, Mariachiara, Kinspergher, Stefania, Prokop, Larry, Grandi, Guido, Inchiostro, Sandro, Paolazzi, Giuseppe, Caffo, Orazio, Veccia, Antonello
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Netherlands Elsevier B.V 01.06.2021
Schlagworte:	Humans Immune Checkpoint Inhibitors Immune related adverse event Immunotherapy - adverse effects Lung cancer Lung Neoplasms - drug therapy Meta-analysis Nivolumab - adverse effects Randomized clinical trials Immune checkpoint inhibitors Randomized clinical trials Immune related adverse event Lung cancer Meta-analysis
ISSN:	1040-8428, 1879-0461, 1879-0461
Online-Zugang:	Volltext
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