Extensive protein dosage compensation in aneuploid human cancers

Aneuploidy is a hallmark of human cancers, but the effects of aneuploidy on protein expression remain poorly understood. To uncover how chromosome copy number changes influence the cancer proteome, we conducted an analysis of hundreds of human cancer cell lines and tumors with matched copy number, R...

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Bibliographic Details

Published in:	Genome research Vol. 32; no. 7; p. 1254
Main Authors:	Schukken, Klaske M, Sheltzer, Jason M
Format:	Journal Article
Language:	English
Published:	United States 01.07.2022
Subjects:	Aneuploidy Chromosomes Dosage Compensation, Genetic Gene Dosage Humans Neoplasms - genetics
ISSN:	1549-5469, 1549-5469
Online Access:	Get more information
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