Characterization and Application of Precore/Core‐Related Antigens in Animal Models of Hepatitis B Virus Infection

Background and Aims The hepatitis B core‐related antigen (HBcrAg), a composite antigen of precore/core gene including classical hepatitis B core protein (HBc) and HBeAg and, additionally, the precore‐related antigen PreC, retaining the N‐terminal signal peptide, has emerged as a surrogate marker to...

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Bibliographic Details
Published in:	Hepatology (Baltimore, Md.) Vol. 74; no. 1; pp. 99 - 115
Main Authors:	Hong, Xupeng, Luckenbaugh, Laurie, Perlman, David, Revill, Peter A., Wieland, Stefan F., Menne, Stephan, Hu, Jianming
Format:	Journal Article
Language:	English
Published:	United States Wolters Kluwer Health, Inc 01.07.2021
Subjects:	Animal models Animals Antigen processing Antigens Antiviral drugs Biopsy Circular DNA Core protein DNA, Viral - isolation & purification Glycosylation Hepatitis B Hepatitis B - blood Hepatitis B - immunology Hepatitis B - virology Hepatitis B Core Antigens - blood Hepatitis B Core Antigens - immunology Hepatitis B Core Antigens - metabolism Hepatitis B e antigen Hepatitis B e Antigens - blood Hepatitis B e Antigens - immunology Hepatitis B e Antigens - metabolism Hepatitis B virus - genetics Hepatitis B virus - immunology Hepatitis B virus - isolation & purification Hepatitis B virus - pathogenicity Hepatitis B Virus, Woodchuck - genetics Hepatitis B Virus, Woodchuck - immunology Hepatitis B Virus, Woodchuck - isolation & purification Hepatitis B Virus, Woodchuck - pathogenicity Hepatology Liver - pathology Liver - virology Marmota Marmota monax Pan troglodytes Proteins Proteolysis Surface antigens Virions
ISSN:	0270-9139, 1527-3350, 1527-3350
Online Access:	Get full text
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