Relationship between the Expression of Matrix Metalloproteinases and Their Tissue Inhibitors in Patients with Brain Tumors

Matrix metalloproteinases (MMPs) and their inhibitors (TIMPs) play critical roles in regulating processes associated with malignant behavior. These endopeptidases selectively degrade components of the extracellular matrix (ECM), growth factors, and their receptors, contributing to cancer cell invasi...

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Bibliographic Details
Published in:	International journal of molecular sciences Vol. 25; no. 5; p. 2858
Main Authors:	Dibdiakova, Katarina, Majercikova, Zuzana, Galanda, Tomas, Richterova, Romana, Kolarovszki, Branislav, Racay, Peter, Hatok, Jozef
Format:	Journal Article
Language:	English
Published:	Switzerland MDPI AG 01.03.2024 MDPI
Subjects:	Astrocytoma Brain Brain cancer Brain Neoplasms Brain tumors Cancer Care and treatment Extracellular matrix Genes Glioblastoma Gliomas Humans Matrix Metalloproteinase 2 - metabolism Matrix Metalloproteinase 9 - metabolism Medical prognosis Proteases Proteins Radiation therapy RNA Statistical significance Tissue Inhibitor of Metalloproteinase-1 - metabolism Tissue Inhibitor of Metalloproteinases - metabolism Tumors United Kingdom Slovakia metalloproteinases tissue inhibitors brain tumors immunodetection qRT-PCR
ISSN:	1422-0067, 1661-6596, 1422-0067
Online Access:	Get full text
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