A Simultaneous Extraction/Derivatization Strategy for Quantitation of Vitamin D in Dried Blood Spots Using LC–MS/MS: Application to Biomarker Study in Subjects Tested for SARS-CoV-2

Vitamin D plays a critical role in bone development and maintenance, and in other physiological functions. The quantitation of endogenous levels of individual vitamin D and its metabolites is crucial for assessing several disease state conditions. With cases of severe acute respiratory syndrome coro...

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Veröffentlicht in:	International journal of molecular sciences Jg. 24; H. 6; S. 5489
Hauptverfasser:	Chhonker, Yashpal S., Ahmed, Nusrat, Johnston, Christine M., Barnabas, Ruanne V., Murry, Daryl J.
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Switzerland MDPI AG 13.03.2023 MDPI
Schlagworte:	Alfacalcidol Biomarkers Blood Calcifediol Chromatography Chromatography, Liquid - methods Coronaviruses COVID-19 Diagnosis Disease Formic acid Health aspects Humans Infections Ions Medical research Medicine, Experimental Metabolites Organic acids Pandemics Physiological aspects Physiology Plasma Reproducibility of Results Retention SARS-CoV-2 Severe acute respiratory syndrome Severe acute respiratory syndrome coronavirus 2 Tandem Mass Spectrometry - methods Vitamin D Vitamins Massachusetts biomarker LC–MS/MS SARS-CoV-2(+) vitamin D
ISSN:	1422-0067, 1661-6596, 1422-0067
Online-Zugang:	Volltext
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