The autophagic tumor stroma model of cancer or "battery-operated tumor growth" A simple solution to the autophagy paradox

The role of autophagy in tumorigenesis is controversial. Both autophagy inhibitors (chloroquine) and autophagy promoters (rapamycin) block tumorigenesis by unknown mechanism(s). This is called the "Autophagy Paradox". We have recently reported a simple solution to this paradox. We demonstr...

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Vydané v:	Cell cycle (Georgetown, Tex.) Ročník 9; číslo 21; s. 4297 - 4306
Hlavní autori:	Martinez-Outschoorn, Ubaldo E., Whitaker-Menezes, Diana, Pavlides, Stephanos, Chiavarina, Barbara, Bonuccelli, Gloria, Trimmer, Casey, Tsirigos, Aristotelis, Migneco, Gemma, Witkiewicz, Agnieszka K., Balliet, Renee M., Mercier, Isabelle, Wang, Chengwang, Flomenberg, Neal, Howell, Anthony, Lin, Zhao, Caro, Jaime, Pestell, Richard G., Sotgia, Federica, Lisanti, Michael P
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States Taylor & Francis 01.11.2010 Landes Bioscience
Predmet:	Animals Autophagy - physiology Binding Biology Bioscience Calcium Cancer Caveolin 1 - genetics Caveolin 1 - metabolism Cell Cycle DNA Damage Genomic Instability Landes Mice MicroRNAs - metabolism Models, Biological Neoplasms - diagnosis Neoplasms - metabolism Neoplasms - therapy Organogenesis Prognosis Proteins Review Stromal Cells - metabolism
ISSN:	1538-4101, 1551-4005, 1551-4005
On-line prístup:	Získať plný text
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