Curcumin Combined with FOLFOX Chemotherapy Is Safe and Tolerable in Patients with Metastatic Colorectal Cancer in a Randomized Phase IIa Trial

Curcumin is the main active ingredient of the spice turmeric, investigated extensively for putative anticancer properties. This phase IIa open-labelled randomized controlled trial aimed to assess safety, efficacy, quality of life, neurotoxicity, curcuminoids, and C-X-C-motif chemokine ligand 1 (CXCL...

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Veröffentlicht in:	The Journal of nutrition Jg. 149; H. 7; S. 1133
Hauptverfasser:	Howells, Lynne M, Iwuji, Chinenye O O, Irving, Glen R B, Barber, Shaun, Walter, Harriet, Sidat, Zahirah, Griffin-Teall, Nicola, Singh, Rajinder, Foreman, Nalini, Patel, Samita R, Morgan, Bruno, Steward, William P, Gescher, Andreas, Thomas, Anne L, Brown, Karen
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 01.07.2019
Schlagworte:	Administration, Oral Aged Antineoplastic Combined Chemotherapy Protocols - administration & dosage Antineoplastic Combined Chemotherapy Protocols - adverse effects Antineoplastic Combined Chemotherapy Protocols - therapeutic use Colorectal Neoplasms - drug therapy Colorectal Neoplasms - pathology Curcumin - administration & dosage Curcumin - therapeutic use Female Fluorouracil - administration & dosage Fluorouracil - therapeutic use Humans Leucovorin - administration & dosage Leucovorin - therapeutic use Male Middle Aged Neoplasm Metastasis Organoplatinum Compounds - administration & dosage Organoplatinum Compounds - therapeutic use Treatment Outcome FOLFOX chemotherapy metastatic colorectal cancer curcuminoids curcumin randomized controlled trial
ISSN:	1541-6100, 1541-6100
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