Efficacy and Safety of Abatacept in Lupus Nephritis: A Twelve‐Month, Randomized, Double‐Blind Study

Objective To compare the efficacy and safety of intravenous (IV) abatacept, a selective T cell costimulation modulator, versus placebo for the treatment of active class III or IV lupus nephritis, when used on a background of mycophenolate mofetil and glucocorticoids. Methods This was a 12‐month, ran...

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Veröffentlicht in:	Arthritis & rheumatology (Hoboken, N.J.) Jg. 66; H. 2; S. 379 - 389
Hauptverfasser:	Furie, Richard, Nicholls, Kathy, Cheng, Tien‐Tsai, Houssiau, Frederic, Burgos‐Vargas, Ruben, Chen, Shun‐Le, Hillson, Jan L., Meadows‐Shropshire, Stephanie, Kinaszczuk, Michael, Merrill, Joan T.
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States Wiley Subscription Services, Inc 01.02.2014
Schlagworte:	Abatacept Adult Dose-Response Relationship, Drug Double-Blind Method Female Humans Immunoconjugates - therapeutic use Immunosuppressive Agents - therapeutic use Internationality Longitudinal Studies Lupus Lupus Nephritis - drug therapy Male Severity of Illness Index Treatment Outcome
ISSN:	2326-5191, 2326-5205, 2326-5205
Online-Zugang:	Volltext
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