A new petunia flower colour generated by transformation of a mutant with a maize gene
Petunia hybrida is one of the classical subjects of investigation in plants in which the pathway of anthocyanin biosynthesis has been analysed genetically and biochemically. In petunia cyanidin- and delphinidin-derivatives, but no pelargonidin-derivatives are produced as pigments. This is due to the...
Uloženo v:
| Vydáno v: | Nature (London) Ročník 330; číslo 6149; s. 677 |
|---|---|
| Hlavní autoři: | , , , |
| Médium: | Journal Article |
| Jazyk: | angličtina |
| Vydáno: |
England
17.12.1987
|
| Témata: | |
| ISSN: | 0028-0836 |
| On-line přístup: | Zjistit podrobnosti o přístupu |
| Tagy: |
Přidat tag
Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!
|
| Abstract | Petunia hybrida is one of the classical subjects of investigation in plants in which the pathway of anthocyanin biosynthesis has been analysed genetically and biochemically. In petunia cyanidin- and delphinidin-derivatives, but no pelargonidin-derivatives are produced as pigments. This is due to the substrate specificity of the dihydroflavonol 4-reductase of petunia, which cannot reduce dihydrokaempferol. The petunia mutant RL01, which accumulates dihydrokaempferol, shows no flower pigmentation. RL01 served as a recipient for the transfer of the A1 gene of Zea mays encoding dihydroquercetin 4-reductase, which can reduce dihydrokaempferol and thereby provided the intermediate for pelargonidin biosynthesis. Transformation of RL01 with a vector p35A1, containing the A1-complementary DNA behind the 35S promotor leads to red flowers of the pelargonidin-type. Thus a new flower pigmentation pathway has been established in these plants. |
|---|---|
| AbstractList | Petunia hybrida is one of the classical subjects of investigation in plants in which the pathway of anthocyanin biosynthesis has been analysed genetically and biochemically. In petunia cyanidin- and delphinidin-derivatives, but no pelargonidin-derivatives are produced as pigments. This is due to the substrate specificity of the dihydroflavonol 4-reductase of petunia, which cannot reduce dihydrokaempferol. The petunia mutant RL01, which accumulates dihydrokaempferol, shows no flower pigmentation. RL01 served as a recipient for the transfer of the A1 gene of Zea mays encoding dihydroquercetin 4-reductase, which can reduce dihydrokaempferol and thereby provided the intermediate for pelargonidin biosynthesis. Transformation of RL01 with a vector p35A1, containing the A1-complementary DNA behind the 35S promotor leads to red flowers of the pelargonidin-type. Thus a new flower pigmentation pathway has been established in these plants.Petunia hybrida is one of the classical subjects of investigation in plants in which the pathway of anthocyanin biosynthesis has been analysed genetically and biochemically. In petunia cyanidin- and delphinidin-derivatives, but no pelargonidin-derivatives are produced as pigments. This is due to the substrate specificity of the dihydroflavonol 4-reductase of petunia, which cannot reduce dihydrokaempferol. The petunia mutant RL01, which accumulates dihydrokaempferol, shows no flower pigmentation. RL01 served as a recipient for the transfer of the A1 gene of Zea mays encoding dihydroquercetin 4-reductase, which can reduce dihydrokaempferol and thereby provided the intermediate for pelargonidin biosynthesis. Transformation of RL01 with a vector p35A1, containing the A1-complementary DNA behind the 35S promotor leads to red flowers of the pelargonidin-type. Thus a new flower pigmentation pathway has been established in these plants. Petunia hybrida is one of the classical subjects of investigation in plants in which the pathway of anthocyanin biosynthesis has been analysed genetically and biochemically. In petunia cyanidin- and delphinidin-derivatives, but no pelargonidin-derivatives are produced as pigments. This is due to the substrate specificity of the dihydroflavonol 4-reductase of petunia, which cannot reduce dihydrokaempferol. The petunia mutant RL01, which accumulates dihydrokaempferol, shows no flower pigmentation. RL01 served as a recipient for the transfer of the A1 gene of Zea mays encoding dihydroquercetin 4-reductase, which can reduce dihydrokaempferol and thereby provided the intermediate for pelargonidin biosynthesis. Transformation of RL01 with a vector p35A1, containing the A1-complementary DNA behind the 35S promotor leads to red flowers of the pelargonidin-type. Thus a new flower pigmentation pathway has been established in these plants. |
| Author | Meyer, P Heidmann, I Saedler, H Forkmann, G |
| Author_xml | – sequence: 1 givenname: P surname: Meyer fullname: Meyer, P organization: Max-Planck-Institut für Züchtungsforschung, Köln, FRG – sequence: 2 givenname: I surname: Heidmann fullname: Heidmann, I – sequence: 3 givenname: G surname: Forkmann fullname: Forkmann, G – sequence: 4 givenname: H surname: Saedler fullname: Saedler, H |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/3683587$$D View this record in MEDLINE/PubMed |
| BookMark | eNotkE1Lw0AYhPdQqW0V_APCnrxF381mP3IsRatQ8GLPYZO8q5Fkt-5uCPXXW7WnYeCZYZglmTnvkJAbBvcMuH7gHKRSBmZkAZDrDDSXl2QZ4ycACKaKOZlzqbnQakH2a-pwogdMo-sMtb2fMNDG934M9B0dBpOwpfWRpmBctD4MJnXeUW-pocOYjEt06tLHrzPdN_6FrsiFNX3E67OuyP7p8W3znO1ety-b9S5rClWmTCiJomFWCWyV5FxrI0othS0Nq60uGmi5ZILhaTZnytomRwtYF0WOsuZlviJ3_72H4L9GjKkauthg3xuHfoyVUloAZ3ACb8_gWA_YVofQDSYcq_MP-Q8zpF2G |
| CitedBy_id | crossref_primary_10_1016_j_biotechadv_2018_11_005 crossref_primary_10_1016_S0021_9258_18_42777_9 crossref_primary_10_1007_s00122_016_2804_1 crossref_primary_10_1016_j_jarmap_2024_100539 crossref_primary_10_1079_IVP2005681 crossref_primary_10_3389_fpls_2021_761862 crossref_primary_10_1111_j_1439_0523_1991_tb00474_x crossref_primary_10_1016_j_jplph_2006_03_001 crossref_primary_10_3390_ijms11030807 crossref_primary_10_3390_ijms222111945 crossref_primary_10_3390_molecules16010251 crossref_primary_10_3390_ijms222312824 crossref_primary_10_1111_pbi_14522 crossref_primary_10_1079_NRR19880015 crossref_primary_10_5511_plantbiotechnology_10_0610a crossref_primary_10_1016_S0014_5793_02_03583_4 crossref_primary_10_1007_s00122_009_1100_8 crossref_primary_10_1016_S0168_9452_02_00433_8 crossref_primary_10_1104_pp_127_1_46 crossref_primary_10_1007_s00253_011_3449_2 crossref_primary_10_1186_s12870_023_04041_0 crossref_primary_10_1007_BF00014927 crossref_primary_10_1111_pbi_12234 crossref_primary_10_1007_s00709_023_01883_1 crossref_primary_10_1007_BF00260483 crossref_primary_10_1016_j_scienta_2023_112182 crossref_primary_10_1016_j_copbio_2008_02_015 crossref_primary_10_1007_BF00023968 crossref_primary_10_1007_BF03030577 crossref_primary_10_1146_annurev_genet_120213_092053 crossref_primary_10_11623_frj_2019_27_4_03 crossref_primary_10_5511_plantbiotechnology_21_377 crossref_primary_10_1111_ppl_12762 crossref_primary_10_1080_03036758_2022_2034654 crossref_primary_10_1016_j_indcrop_2024_118374 crossref_primary_10_3390_genes10080559 crossref_primary_10_1007_s11033_023_08420_6 crossref_primary_10_1007_BF00023973 crossref_primary_10_1007_s00425_015_2349_6 crossref_primary_10_2478_fhort_2019_0001 crossref_primary_10_3390_ijms23137187 crossref_primary_10_1007_BF00280469 crossref_primary_10_1007_s11240_008_9460_3 crossref_primary_10_1016_j_jgeb_2024_100354 crossref_primary_10_1080_15592324_2020_1721044 crossref_primary_10_1038_nbt0493_508 crossref_primary_10_1016_j_indcrop_2020_112838 crossref_primary_10_7717_peerj_12323 crossref_primary_10_1016_j_scienta_2013_05_024 crossref_primary_10_1023_A_1005881032409 crossref_primary_10_1111_j_1365_313X_1992_00465_x crossref_primary_10_1300_J411v17n01_08 crossref_primary_10_7717_peerj_16124 crossref_primary_10_1007_s10681_005_5037_y crossref_primary_10_1094_MPMI_1997_10_9_1065 crossref_primary_10_1016_S0304_4238_97_00122_2 crossref_primary_10_3390_ijms20194743 crossref_primary_10_1007_s10529_005_1521_7 crossref_primary_10_1007_BF02191704 crossref_primary_10_1007_s11248_011_9566_y crossref_primary_10_1016_S0958_1669_00_00192_0 crossref_primary_10_1371_journal_pone_0074395 crossref_primary_10_1023_B_BILE_0000003989_19657_53 crossref_primary_10_1016_S0168_9452_96_04544_X crossref_primary_10_1016_S0168_9452_99_00072_2 crossref_primary_10_1023_A_1026364618719 crossref_primary_10_1111_j_1432_1033_1990_tb19262_x crossref_primary_10_1007_BF00021810 crossref_primary_10_1016_j_biotechadv_2004_06_002 crossref_primary_10_1111_ppl_13921 crossref_primary_10_17221_31_2024_HORTSCI crossref_primary_10_1111_j_1744_7909_2005_00148_x crossref_primary_10_1007_s00299_014_1617_4 crossref_primary_10_1016_0168_9452_93_90127_L crossref_primary_10_1111_j_1438_8677_1992_tb01306_x crossref_primary_10_1016_j_ijbiomac_2023_125372 crossref_primary_10_1007_s10529_010_0461_z crossref_primary_10_1046_j_1365_313X_1992_t01_20_00999_x crossref_primary_10_1023_A_1008966404981 crossref_primary_10_1016_j_scienta_2013_08_017 crossref_primary_10_3390_ijms10125350 crossref_primary_10_1038_srep39031 crossref_primary_10_5511_plantbiotechnology_15_0702b crossref_primary_10_1300_J411v18n01_01 crossref_primary_10_3390_horticulturae7090324 crossref_primary_10_1038_s41438_019_0232_5 crossref_primary_10_1007_s11105_023_01417_2 crossref_primary_10_3390_horticulturae7090327 crossref_primary_10_1023_A_1020320809654 crossref_primary_10_1007_s00253_022_11835_z crossref_primary_10_1016_j_febslet_2005_09_073 crossref_primary_10_1007_BF00259446 crossref_primary_10_1038_nbt0994_883 crossref_primary_10_1007_BF00564197 crossref_primary_10_1007_BF00116544 crossref_primary_10_1016_S0031_9422_00_89636_3 crossref_primary_10_1016_S0167_7799_00_88980_5 crossref_primary_10_1111_j_1467_7652_2012_00693_x crossref_primary_10_1371_journal_pone_0112707 crossref_primary_10_1007_BF00036968 crossref_primary_10_1007_BF02671358 crossref_primary_10_1134_S1068162010020020 crossref_primary_10_3733_ca_v054n04p49 crossref_primary_10_3390_ijms241813901 crossref_primary_10_1023_A_1005841214470 crossref_primary_10_1007_BF01976503 crossref_primary_10_3389_fpls_2023_1227219 crossref_primary_10_1038_s41598_020_71614_6 crossref_primary_10_3390_plants14071050 crossref_primary_10_1016_S0168_9452_97_04624_4 crossref_primary_10_3389_fpls_2016_00153 crossref_primary_10_12688_f1000research_122453_1 crossref_primary_10_1016_S0031_9422_00_94773_3 crossref_primary_10_1007_s00425_017_2722_8 crossref_primary_10_1016_j_biotechadv_2020_107600 crossref_primary_10_1007_s12033_022_00523_y crossref_primary_10_1007_s11240_020_01871_w crossref_primary_10_5511_plantbiotechnology_25_3 crossref_primary_10_1093_ajcn_58_2_270S crossref_primary_10_1016_0168_1656_92_90067_J crossref_primary_10_1093_plphys_kiad424 crossref_primary_10_1007_BF00292701 crossref_primary_10_3389_fpls_2015_00751 crossref_primary_10_1016_j_plantsci_2024_112370 crossref_primary_10_1007_BF00290650 crossref_primary_10_1080_07352689209382324 crossref_primary_10_3390_plants10030472 crossref_primary_10_1104_pp_109_152801 crossref_primary_10_1007_s11032_020_01176_y crossref_primary_10_3390_ijms232416123 crossref_primary_10_1016_j_pbi_2020_04_001 crossref_primary_10_3390_plants12233983 crossref_primary_10_1007_s13205_017_0870_y crossref_primary_10_1007_s11101_007_9074_0 crossref_primary_10_1007_s00299_007_0401_0 crossref_primary_10_1093_pcp_pcu097 crossref_primary_10_1038_s41598_019_43463_5 crossref_primary_10_1016_0031_9422_90_83027_X crossref_primary_10_1023_A_1009657923408 crossref_primary_10_1186_s40529_016_0138_6 crossref_primary_10_1007_BF01681809 crossref_primary_10_1016_0168_9452_90_90051_O crossref_primary_10_1016_0167_7799_94_90097_3 crossref_primary_10_5511_plantbiotechnology_19_377 crossref_primary_10_1080_14620316_2018_1543558 crossref_primary_10_3390_molecules23061467 crossref_primary_10_1111_j_1478_4408_1995_tb00100_x crossref_primary_10_1038_333866a0 crossref_primary_10_1016_0168_1656_89_90125_9 crossref_primary_10_3389_fpls_2015_00139 crossref_primary_10_1111_j_1469_8137_1996_tb04921_x crossref_primary_10_1016_j_scienta_2022_111158 crossref_primary_10_1007_s13237_021_00368_x crossref_primary_10_1007_BF01974088 crossref_primary_10_3389_fpls_2017_00279 crossref_primary_10_1007_BF02101785 crossref_primary_10_1016_S1369_703X_02_00224_3 crossref_primary_10_1155_2022_1382604 crossref_primary_10_3390_plants9060687 crossref_primary_10_1016_j_tplants_2005_03_005 crossref_primary_10_1016_j_scienta_2020_109476 crossref_primary_10_1371_journal_pone_0072017 crossref_primary_10_1046_j_1365_313x_2001_00962_x crossref_primary_10_1104_pp_103_030221 crossref_primary_10_5511_plantbiotechnology_23_19 crossref_primary_10_1007_BF00633837 crossref_primary_10_1016_S1360_1385_98_01242_4 crossref_primary_10_1007_s00344_009_9126_3 crossref_primary_10_1016_j_dyepig_2022_110925 crossref_primary_10_1080_01140671_2013_793730 crossref_primary_10_1016_S0734_9750_97_00063_3 crossref_primary_10_3389_fpls_2020_01047 crossref_primary_10_1111_pbr_12520 crossref_primary_10_1080_07388551_2016_1237467 crossref_primary_10_3389_fpls_2014_00620 crossref_primary_10_1016_0958_1669_93_90117_F crossref_primary_10_3389_fpls_2018_00149 crossref_primary_10_3390_molecules21020032 crossref_primary_10_1186_s12870_018_1539_3 crossref_primary_10_3389_fpls_2021_737815 crossref_primary_10_1134_S1021443706020129 crossref_primary_10_1016_0304_4238_93_90029_P crossref_primary_10_5010_JPB_2003_30_2_143 crossref_primary_10_1007_s13205_024_04016_4 crossref_primary_10_1080_07352680701429381 crossref_primary_10_1270_jsbbs_17132 crossref_primary_10_1016_j_scienta_2013_12_009 crossref_primary_10_1038_s41598_021_95071_x crossref_primary_10_1104_pp_117_2_711 crossref_primary_10_1111_j_1439_0523_1995_tb00752_x crossref_primary_10_1023_A_1002967607727 crossref_primary_10_1007_BF00025316 crossref_primary_10_1371_journal_pone_0119054 crossref_primary_10_3390_molecules23040861 crossref_primary_10_1007_s00425_010_1142_9 crossref_primary_10_1016_j_plaphy_2018_03_015 crossref_primary_10_1007_s00299_023_02983_1 |
| ContentType | Journal Article |
| DBID | CGR CUY CVF ECM EIF NPM 7X8 |
| DOI | 10.1038/330677a0 |
| DatabaseName | Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed MEDLINE - Academic |
| DatabaseTitle | MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) MEDLINE - Academic |
| DatabaseTitleList | MEDLINE - Academic MEDLINE |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: 7X8 name: MEDLINE - Academic url: https://search.proquest.com/medline sourceTypes: Aggregation Database |
| DeliveryMethod | no_fulltext_linktorsrc |
| Discipline | Sciences (General) Physics |
| ExternalDocumentID | 3683587 |
| Genre | Journal Article |
| GroupedDBID | --- --Z -DZ -ET -~X .-4 .55 .GJ .HR 0R~ 0WA 123 186 1CY 29M 2KS 3EH 3O- 4.4 42X 53G 5RE 6TJ 85S 8WZ 9M8 A6W A7Z AAEEF AAHBH AAHTB AAIKC AAKAB AAMNW AAYOK AAYZH ABAWZ ABDPE ABEFU ABIVO ABJNI ABLJU ABNNU ABOCM ABPEJ ABPPZ ABTAH ABWJO ACBEA ACBTR ACGFO ACGFS ACGOD ACIWK ACKOT ACMJI ACNCT ACPRK ACRPL ACTDY ACWUS ADBBV ADFRT ADNMO ADUKH AENEX AFFDN AFFNX AFLOW AFRAH AFSHS AGAYW AGGDT AGHSJ AGHTU AGNAY AGSOS AHMBA AIDAL AIDUJ AIYXT AJUXI ALFFA ALIPV ALMA_UNASSIGNED_HOLDINGS AMTXH ASPBG AVWKF AXYYD AZFZN BIN BKKNO CGR CJ0 CS3 CUY CVF DB5 DU5 E.- E.L EBS ECM EE. EIF EJD EMH EXGXG F5P FA8 FQGFK FSGXE HG6 HZ~ IAO IH2 INH IOF J5H KOO L-9 L7B M2M MVM N9A NEJ NEPJS NPM O9- OHT OMK P-O P2P PKN RND RNS RNT RNTTT RXW SC5 SJN SNYQT SOJ TAOOD TEORI TN5 TSG TWZ U5U UBY UHB UKR UQL VOH VQA VVN WH7 X7M XKW XOL XZL Y6R YIF YIN YNT YOC YQJ YQT YR2 YXB YYP YYQ YZZ Z5M ZCA ZCG ZGI ZKB ZY4 ~02 ~KM 7X8 AARCD ADXHL AETEA AFANA AGQPQ ALPWD ATHPR |
| ID | FETCH-LOGICAL-c479t-576e5c1f75ed763388a59865f9a1bf84c0d36151e051317ffc2ef0eb442e6b392 |
| IEDL.DBID | 7X8 |
| ISICitedReferencesCount | 282 |
| ISICitedReferencesURI | http://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=Summon&SrcAuth=ProQuest&DestLinkType=CitingArticles&DestApp=WOS_CPL&KeyUT=10_1038_330677a0&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D |
| ISSN | 0028-0836 |
| IngestDate | Thu Oct 02 18:08:35 EDT 2025 Wed Feb 19 01:10:27 EST 2025 |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 6149 |
| Language | English |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c479t-576e5c1f75ed763388a59865f9a1bf84c0d36151e051317ffc2ef0eb442e6b392 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
| PMID | 3683587 |
| PQID | 77850310 |
| PQPubID | 23479 |
| ParticipantIDs | proquest_miscellaneous_77850310 pubmed_primary_3683587 |
| PublicationCentury | 1900 |
| PublicationDate | 1987-12-17 |
| PublicationDateYYYYMMDD | 1987-12-17 |
| PublicationDate_xml | – month: 12 year: 1987 text: 1987-12-17 day: 17 |
| PublicationDecade | 1980 |
| PublicationPlace | England |
| PublicationPlace_xml | – name: England |
| PublicationTitle | Nature (London) |
| PublicationTitleAlternate | Nature |
| PublicationYear | 1987 |
| SSID | ssj0005174 |
| Score | 1.724693 |
| Snippet | Petunia hybrida is one of the classical subjects of investigation in plants in which the pathway of anthocyanin biosynthesis has been analysed genetically and... |
| SourceID | proquest pubmed |
| SourceType | Aggregation Database Index Database |
| StartPage | 677 |
| SubjectTerms | DNA, Recombinant Flavonols Oxidoreductases - genetics Pigmentation Pigments, Biological - biosynthesis Plants - genetics Quercetin - analogs & derivatives Quercetin - metabolism Transformation, Genetic Zea mays - genetics |
| Title | A new petunia flower colour generated by transformation of a mutant with a maize gene |
| URI | https://www.ncbi.nlm.nih.gov/pubmed/3683587 https://www.proquest.com/docview/77850310 |
| Volume | 330 |
| WOSCitedRecordID | wos10_1038_330677a0&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D |
| hasFullText | |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpZ1NS8NAEIaHahW8qK0W6-cePOghNGmS7gYEEbF40NKDld7C7mZXCprUphX01zuTJiiCePASCGQg7M5Onp2dvANwGmo30dxEDveN6wSeDBykIuVIL5Ju4iVJr5BSerzjg4EYj6NhDS6qf2GorLKKiUWgTjJNOfIO5yIkGcvL6atDPaPobLVsoLECdR9Bhnyaj7-0wn9qMFfSs77o-ATKXLq_Y2Xxeelv_e_FtmGzxEp2tfSDBtRM2oT1orxT501olEs4Z2elzvT5DoyuGDI1Q2xepBPJ7DM1TGOkYr2YsafiMcRRpt7Z_BvdZinLLJPsZUH9hxnlcelOTj5MYbQLo_7Nw_WtU3ZZcHTAo7mDGw4Tas_y0CQYbHwhJGm2hzaSnrIiwMn0CXsMDijChrW6a6xrVBB0TU8hXrVgNc1SswdMeT2hheqG2gSBVgb3KqRug5CnktBo1YaTaghj9GI6mpCpyRZ5XA1iG1rLWYinS7GN2O-hueD7f5oewAYlUKjUxOOHULe4fM0RrOm3-SSfHRe-gdfB8P4Tb0_EFA |
| linkProvider | ProQuest |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=A+new+petunia+flower+colour+generated+by+transformation+of+a+mutant+with+a+maize+gene&rft.jtitle=Nature+%28London%29&rft.au=Meyer%2C+P&rft.au=Heidmann%2C+I&rft.au=kmann%2C+G&rft.au=Saedler%2C+H&rft.date=1987-12-17&rft.issn=0028-0836&rft.volume=330&rft.issue=6149&rft.spage=677&rft_id=info:doi/10.1038%2F330677a0&rft.externalDBID=NO_FULL_TEXT |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0028-0836&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0028-0836&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0028-0836&client=summon |