Tirofiban potentiates agonist-induced platelet activation and degranulation, despite effectively inhibiting aggregation

We aimed to investigate the effects of integrin αIIbβ3 inhibitor tirofiban on hallmarks of platelet activation, degranulation, and aggregation during its use to analyze activated but non-complexed platelets via flow cytometry. To do so, we used washed platelets from healthy human donors. We combined...

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Vydané v:	Platelets (Edinburgh) Ročník 33; číslo 8; s. 1192 - 1198
Hlavní autori:	Aguiar Bucsai, Martina, Idel, Christian, Wollenberg, Barbara, Mannhalter, Christine, Verschoor, Admar
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	England Taylor & Francis 17.11.2022 Taylor & Francis Group
Predmet:	platelet activation platelet aggregation platelet degranulation platelet inhibition tirofiban platelet inhibition platelet degranulation tirofiban platelet activation platelet aggregation
ISSN:	0953-7104, 1369-1635, 1369-1635
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