MiR-126-3p Is Dynamically Regulated in Endothelial-to-Mesenchymal Transition during Fibrosis

In fibrotic diseases, myofibroblasts derive from a range of cell types including endothelial-to-mesenchymal transition (EndMT). Increasing evidence suggests that miRNAs are key regulators in biological processes but their profile is relatively understudied in EndMT. In human umbilical vein endotheli...

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Veröffentlicht in:	International journal of molecular sciences Jg. 22; H. 16; S. 8629
Hauptverfasser:	Jordan, Nina P., Tingle, Samuel J., Shuttleworth, Victoria G., Cooke, Katie, Redgrave, Rachael E., Singh, Esha, Glover, Emily K., Ahmad Tajuddin, Hafiza B., Kirby, John A., Arthur, Helen M., Ward, Chris, Sheerin, Neil S., Ali, Simi
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Switzerland MDPI AG 11.08.2021 MDPI
Schlagworte:	Animals Cell Transdifferentiation - genetics Cells, Cultured Endothelial Cells - pathology Endothelial Cells - physiology Fibroblasts Fibrosis - genetics Gene expression Heart attacks Human Umbilical Vein Endothelial Cells - metabolism Human Umbilical Vein Endothelial Cells - pathology Human Umbilical Vein Endothelial Cells - physiology Humans Kidney - metabolism Kidney - pathology Kidneys Mesenchymal Stem Cells - physiology Mice Mice, Inbred C57BL MicroRNAs MicroRNAs - physiology Myocardium - metabolism Myocardium - pathology Myofibroblasts - metabolism Myofibroblasts - pathology Proteins Transplants & implants endothelial-to-mesenchymal transition microRNA miR-126 fibrosis
ISSN:	1422-0067, 1661-6596, 1422-0067
Online-Zugang:	Volltext
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