Climate change and nephrology
Climate change should be of special concern for the nephrologist, as the kidney has a critical role in protecting the host from dehydration, but it is also a favorite target of heat stress and dehydration. Here we discuss how rising temperatures and extreme heat events may affect the kidney. The mos...
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| Published in: | Nephrology, dialysis, transplantation Vol. 38; no. 1; p. 41 |
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| Main Authors: | , , , , , , , , , , , , , , , |
| Format: | Journal Article |
| Language: | English |
| Published: |
England
23.01.2023
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| ISSN: | 1460-2385, 1460-2385 |
| Online Access: | Get more information |
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| Abstract | Climate change should be of special concern for the nephrologist, as the kidney has a critical role in protecting the host from dehydration, but it is also a favorite target of heat stress and dehydration. Here we discuss how rising temperatures and extreme heat events may affect the kidney. The most severe presentation of heat stress is heat stroke, which can result in severe electrolyte disturbance and both acute and chronic kidney disease (CKD). However, lesser levels of heat stress also have multiple effects, including exacerbating kidney disease and precipitating cardiovascular events in subjects with established kidney disease. Heat stress can also increase the risk for kidney stones, cause multiple electrolyte abnormalities and induce both acute and chronic kidney disease. Recently there have been multiple epidemics of CKD of uncertain etiology in various regions of the world, including Mesoamerica, Sri Lanka, India and Thailand. There is increasing evidence that climate change and heat stress may play a contributory role in these conditions, although other causes, including toxins, could also be involved. As climate change worsens, the nephrologist should prepare for an increase in diseases associated with heat stress and dehydration. |
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| AbstractList | Climate change should be of special concern for the nephrologist, as the kidney has a critical role in protecting the host from dehydration, but it is also a favorite target of heat stress and dehydration. Here we discuss how rising temperatures and extreme heat events may affect the kidney. The most severe presentation of heat stress is heat stroke, which can result in severe electrolyte disturbance and both acute and chronic kidney disease (CKD). However, lesser levels of heat stress also have multiple effects, including exacerbating kidney disease and precipitating cardiovascular events in subjects with established kidney disease. Heat stress can also increase the risk for kidney stones, cause multiple electrolyte abnormalities and induce both acute and chronic kidney disease. Recently there have been multiple epidemics of CKD of uncertain etiology in various regions of the world, including Mesoamerica, Sri Lanka, India and Thailand. There is increasing evidence that climate change and heat stress may play a contributory role in these conditions, although other causes, including toxins, could also be involved. As climate change worsens, the nephrologist should prepare for an increase in diseases associated with heat stress and dehydration.Climate change should be of special concern for the nephrologist, as the kidney has a critical role in protecting the host from dehydration, but it is also a favorite target of heat stress and dehydration. Here we discuss how rising temperatures and extreme heat events may affect the kidney. The most severe presentation of heat stress is heat stroke, which can result in severe electrolyte disturbance and both acute and chronic kidney disease (CKD). However, lesser levels of heat stress also have multiple effects, including exacerbating kidney disease and precipitating cardiovascular events in subjects with established kidney disease. Heat stress can also increase the risk for kidney stones, cause multiple electrolyte abnormalities and induce both acute and chronic kidney disease. Recently there have been multiple epidemics of CKD of uncertain etiology in various regions of the world, including Mesoamerica, Sri Lanka, India and Thailand. There is increasing evidence that climate change and heat stress may play a contributory role in these conditions, although other causes, including toxins, could also be involved. As climate change worsens, the nephrologist should prepare for an increase in diseases associated with heat stress and dehydration. Climate change should be of special concern for the nephrologist, as the kidney has a critical role in protecting the host from dehydration, but it is also a favorite target of heat stress and dehydration. Here we discuss how rising temperatures and extreme heat events may affect the kidney. The most severe presentation of heat stress is heat stroke, which can result in severe electrolyte disturbance and both acute and chronic kidney disease (CKD). However, lesser levels of heat stress also have multiple effects, including exacerbating kidney disease and precipitating cardiovascular events in subjects with established kidney disease. Heat stress can also increase the risk for kidney stones, cause multiple electrolyte abnormalities and induce both acute and chronic kidney disease. Recently there have been multiple epidemics of CKD of uncertain etiology in various regions of the world, including Mesoamerica, Sri Lanka, India and Thailand. There is increasing evidence that climate change and heat stress may play a contributory role in these conditions, although other causes, including toxins, could also be involved. As climate change worsens, the nephrologist should prepare for an increase in diseases associated with heat stress and dehydration. |
| Author | Brown, Jared M Dawson, Jaime Butler Newman, Lee S Glaser, Jason Hernando, Ana Andres Sasai, Fumihiko Rodriguez-Iturbe, Bernardo Garcia, Gabriela Roncal-Jimenez, Carlos Sanchez-Lozada, Laura Gabriela Lanaspa, Miguel Rogers, Keegan Gonzalez-Quiroz, Marvin Sato, Yuka Johnson, Richard J Sorensen, Cecilia |
| Author_xml | – sequence: 1 givenname: Fumihiko surname: Sasai fullname: Sasai, Fumihiko organization: Division of Renal Diseases and Hypertension, University of Colorado Anschutz Medical Campus, Aurora, CO, USA – sequence: 2 givenname: Carlos surname: Roncal-Jimenez fullname: Roncal-Jimenez, Carlos organization: Division of Renal Diseases and Hypertension, University of Colorado Anschutz Medical Campus, Aurora, CO, USA – sequence: 3 givenname: Keegan surname: Rogers fullname: Rogers, Keegan organization: Department of Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, CO, USA – sequence: 4 givenname: Yuka surname: Sato fullname: Sato, Yuka organization: Department of Nephrology, Nagoya University Graduate School of Medicine, Nagoya, Japan – sequence: 5 givenname: Jared M surname: Brown fullname: Brown, Jared M organization: Department of Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, CO, USA – sequence: 6 givenname: Jason surname: Glaser fullname: Glaser, Jason organization: La Isla Network, Léon, Nicaragua – sequence: 7 givenname: Gabriela surname: Garcia fullname: Garcia, Gabriela organization: Division of Renal Diseases and Hypertension, University of Colorado Anschutz Medical Campus, Aurora, CO, USA – sequence: 8 givenname: Laura Gabriela surname: Sanchez-Lozada fullname: Sanchez-Lozada, Laura Gabriela organization: Laboratory of Renal Physiopathology, Instituto Nacional de Cardiologia, Ignacio Chavez, Mexico City – sequence: 9 givenname: Bernardo surname: Rodriguez-Iturbe fullname: Rodriguez-Iturbe, Bernardo organization: Instituto Nacional de Cencias Médicas y Nutrición "Salvador Zubirán", Department of Nephrology, Mexico City, Mexico – sequence: 10 givenname: Jaime Butler surname: Dawson fullname: Dawson, Jaime Butler organization: Center for Health, Work and Environment, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, CO, USA – sequence: 11 givenname: Cecilia surname: Sorensen fullname: Sorensen, Cecilia organization: Center for Health, Work and Environment, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, CO, USA – sequence: 12 givenname: Ana Andres surname: Hernando fullname: Hernando, Ana Andres organization: Division of Renal Diseases and Hypertension, University of Colorado Anschutz Medical Campus, Aurora, CO, USA – sequence: 13 givenname: Marvin surname: Gonzalez-Quiroz fullname: Gonzalez-Quiroz, Marvin organization: Centre for Nephrology, University College London, London, UK – sequence: 14 givenname: Miguel surname: Lanaspa fullname: Lanaspa, Miguel organization: Division of Renal Diseases and Hypertension, University of Colorado Anschutz Medical Campus, Aurora, CO, USA – sequence: 15 givenname: Lee S surname: Newman fullname: Newman, Lee S organization: Center for Health, Work and Environment, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, CO, USA – sequence: 16 givenname: Richard J surname: Johnson fullname: Johnson, Richard J organization: Division of Renal Diseases and Hypertension, University of Colorado Anschutz Medical Campus, Aurora, CO, USA |
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| Keywords | heat stress global warming Mesoamerican nephropathy CKD of non-traditional cause nephrolithiasis CKD of uncertain etiology dehydration Sri Lankan nephropathy heat stroke CKD of unknown etiology |
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