A Review of Exosomal Isolation Methods: Is Size Exclusion Chromatography the Best Option?

Extracellular vesicles (EVs) are membranous vesicles secreted by both prokaryotic and eukaryotic cells and play a vital role in intercellular communication. EVs are classified into several subtypes based on their origin, physical characteristics, and biomolecular makeup. Exosomes, a subtype of EVs,...

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Bibliographic Details
Published in:	International journal of molecular sciences Vol. 21; no. 18; p. 6466
Main Authors:	Sidhom, Karim, Obi, Patience O., Saleem, Ayesha
Format:	Journal Article
Language:	English
Published:	Switzerland MDPI AG 04.09.2020 MDPI
Subjects:	Animals Chromatography Chromatography, Gel - methods Communication Deoxyribonucleic acid DNA Exosomes - chemistry Exosomes - metabolism Extracellular vesicles Extracellular Vesicles - chemistry Extracellular Vesicles - metabolism Humans Membranes MicroRNAs Mitochondrial DNA Pore size Proteins Review Sedimentation & deposition Ultracentrifugation - methods Ultrafiltration - methods extracellular vesicles exosomes size-exclusion chromatography immunoaffinity capture poly-ethylene glycol microvesicles differential ultracentrifugation microfluidics
ISSN:	1422-0067, 1661-6596, 1422-0067
Online Access:	Get full text
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