Monogenic diabetes in overweight and obese youth diagnosed with type 2 diabetes: the TODAY clinical trial

Purpose Monogenic diabetes accounts for 1–2% of diabetes cases. It is often undiagnosed, which may lead to inappropriate treatment. This study was performed to estimate the prevalence of monogenic diabetes in a cohort of overweight/obese adolescents diagnosed with type 2 diabetes (T2D). Methods Sequ...

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Bibliographic Details
Published in:	Genetics in medicine Vol. 20; no. 6; pp. 583 - 590
Main Authors:	Kleinberger, Jeffrey W, Copeland, Kenneth C, Gandica, Rachelle G, Haymond, Morey W, Levitsky, Lynne L, Linder, Barbara, Shuldiner, Alan R, Tollefsen, Sherida, White, Neil H, Pollin, Toni I
Format:	Journal Article
Language:	English
Published:	New York Nature Publishing Group US 01.06.2018 Elsevier Limited
Subjects:	692/308/2779/109 692/699/2743/137/773 692/699/2743/393 692/700/139 Adolescent Biomedical and Life Sciences Biomedicine Body Mass Index Child Clinical trials Cohort Studies Diabetes Diabetes Mellitus, Type 2 - genetics Diabetes Mellitus, Type 2 - metabolism Female Germinal Center Kinases Hepatocyte Nuclear Factor 1-alpha - genetics Hepatocyte Nuclear Factor 1-alpha - metabolism Hepatocyte Nuclear Factor 4 - genetics Hepatocyte Nuclear Factor 4 - metabolism Human Genetics Humans Laboratory Medicine Male Obesity Obesity - complications Obesity - genetics original-research-article Overweight - complications Overweight - genetics Protein Serine-Threonine Kinases - genetics Protein Serine-Threonine Kinases - metabolism Teenagers clinical trial type 2 diabetes monogenic diabetes obesity youth
ISSN:	1098-3600, 1530-0366, 1530-0366
Online Access:	Get full text
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