An Overview of Oxidative Stress, Neuroinflammation, and Neurodegenerative Diseases

Oxidative stress has been linked with a variety of diseases, being involved in the debut and/or progress of several neurodegenerative disorders. This review intends to summarize some of the findings that correlate the overproduction of reactive oxygen species with the pathophysiology of Alzheimer’s...

Full description

Saved in:

Bibliographic Details
Published in:	International journal of molecular sciences Vol. 23; no. 11; p. 5938
Main Authors:	Teleanu, Daniel Mihai, Niculescu, Adelina-Gabriela, Lungu, Iulia Ioana, Radu, Crina Ioana, Vladâcenco, Oana, Roza, Eugenia, Costăchescu, Bogdan, Grumezescu, Alexandru Mihai, Teleanu, Raluca Ioana
Format:	Journal Article
Language:	English
Published:	Switzerland MDPI AG 25.05.2022 MDPI
Subjects:	Alzheimer's disease Antioxidants Antioxidants - therapeutic use Cytochrome Cytotoxicity Dehydrogenases Dopamine Enzymes Humans Huntingtons disease Metabolism Mitochondria Neurodegenerative Diseases - pathology Neuroinflammatory Diseases Neurons Oxidation Oxidative stress Oxidative Stress - physiology Parkinson's disease Reactive Oxygen Species Review neurodegenerative disease antioxidants neuroinflammation reactive oxidative species
ISSN:	1422-0067, 1661-6596, 1422-0067
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Abstract	Oxidative stress has been linked with a variety of diseases, being involved in the debut and/or progress of several neurodegenerative disorders. This review intends to summarize some of the findings that correlate the overproduction of reactive oxygen species with the pathophysiology of Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, and amyotrophic lateral sclerosis. Oxidative stress was also noted to modify the inflammatory response. Even though oxidative stress and neuroinflammation are two totally different pathological events, they are linked and affect one another. Nonetheless, there are still several mechanisms that need to be understood regarding the onset and the progress of neurodegenerative diseases in order to develop efficient therapies. As antioxidants are a means to alter oxidative stress and slow down the symptoms of these neurodegenerative diseases, the most common antioxidants, enzymatic as well as non-enzymatic, have been mentioned in this paper as therapeutic options for the discussed disorders.
AbstractList	Oxidative stress has been linked with a variety of diseases, being involved in the debut and/or progress of several neurodegenerative disorders. This review intends to summarize some of the findings that correlate the overproduction of reactive oxygen species with the pathophysiology of Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, and amyotrophic lateral sclerosis. Oxidative stress was also noted to modify the inflammatory response. Even though oxidative stress and neuroinflammation are two totally different pathological events, they are linked and affect one another. Nonetheless, there are still several mechanisms that need to be understood regarding the onset and the progress of neurodegenerative diseases in order to develop efficient therapies. As antioxidants are a means to alter oxidative stress and slow down the symptoms of these neurodegenerative diseases, the most common antioxidants, enzymatic as well as non-enzymatic, have been mentioned in this paper as therapeutic options for the discussed disorders. Oxidative stress has been linked with a variety of diseases, being involved in the debut and/or progress of several neurodegenerative disorders. This review intends to summarize some of the findings that correlate the overproduction of reactive oxygen species with the pathophysiology of Alzheimer's disease, Parkinson's disease, Huntington's disease, and amyotrophic lateral sclerosis. Oxidative stress was also noted to modify the inflammatory response. Even though oxidative stress and neuroinflammation are two totally different pathological events, they are linked and affect one another. Nonetheless, there are still several mechanisms that need to be understood regarding the onset and the progress of neurodegenerative diseases in order to develop efficient therapies. As antioxidants are a means to alter oxidative stress and slow down the symptoms of these neurodegenerative diseases, the most common antioxidants, enzymatic as well as non-enzymatic, have been mentioned in this paper as therapeutic options for the discussed disorders.Oxidative stress has been linked with a variety of diseases, being involved in the debut and/or progress of several neurodegenerative disorders. This review intends to summarize some of the findings that correlate the overproduction of reactive oxygen species with the pathophysiology of Alzheimer's disease, Parkinson's disease, Huntington's disease, and amyotrophic lateral sclerosis. Oxidative stress was also noted to modify the inflammatory response. Even though oxidative stress and neuroinflammation are two totally different pathological events, they are linked and affect one another. Nonetheless, there are still several mechanisms that need to be understood regarding the onset and the progress of neurodegenerative diseases in order to develop efficient therapies. As antioxidants are a means to alter oxidative stress and slow down the symptoms of these neurodegenerative diseases, the most common antioxidants, enzymatic as well as non-enzymatic, have been mentioned in this paper as therapeutic options for the discussed disorders.
Author	Lungu, Iulia Ioana Teleanu, Daniel Mihai Niculescu, Adelina-Gabriela Costăchescu, Bogdan Teleanu, Raluca Ioana Roza, Eugenia Grumezescu, Alexandru Mihai Radu, Crina Ioana Vladâcenco, Oana
AuthorAffiliation	1 “Carol Davila” University of Medicine and Pharmacy, 020021 Bucharest, Romania; daniel.teleanu@umfcd.ro (D.M.T.); oana-aurelia.vladacenco@drd.umfcd.ro (O.V.); eugenia.roza@umfcd.ro (E.R.); raluca.teleanu@umfcd.ro (R.I.T.) 3 National Institute of Laser, Plasma and Radiation Physics (NILPRP), 077125 Magurele, Romania 2 Department of Science and Engineering of Oxide Materials and Nanomaterials, University Politehnica of Bucharest, 011061 Bucharest, Romania; adelina.niculescu@upb.ro (A.-G.N.); iulia.lunguu@gmail.com (I.I.L.) 8 ICUB—Research Institute of University of Bucharest, University of Bucharest, 050657 Bucharest, Romania 9 Academy of Romanian Scientists, Ilfov No. 3, 050044 Bucharest, Romania 6 “Gr. T. Popa” University of Medicine and Pharmacy, 700115 Iasi, Romania; costachescus@gmail.com 7 “Prof. Dr. N. Oblu” Emergency Clinical Hospital, 700309 Iasi, Romania 5 Department of Pediatric Neurology, “Dr. Victor Gomoiu” Children’s Hospital, 022102 Bucharest, Romania 4 Department of Neurosurgery
AuthorAffiliation_xml	– name: 3 National Institute of Laser, Plasma and Radiation Physics (NILPRP), 077125 Magurele, Romania – name: 4 Department of Neurosurgery (I), Bucharest University Emergency Hospital, 050098 Bucharest, Romania; crina.radu95@gmail.com – name: 6 “Gr. T. Popa” University of Medicine and Pharmacy, 700115 Iasi, Romania; costachescus@gmail.com – name: 2 Department of Science and Engineering of Oxide Materials and Nanomaterials, University Politehnica of Bucharest, 011061 Bucharest, Romania; adelina.niculescu@upb.ro (A.-G.N.); iulia.lunguu@gmail.com (I.I.L.) – name: 7 “Prof. Dr. N. Oblu” Emergency Clinical Hospital, 700309 Iasi, Romania – name: 9 Academy of Romanian Scientists, Ilfov No. 3, 050044 Bucharest, Romania – name: 1 “Carol Davila” University of Medicine and Pharmacy, 020021 Bucharest, Romania; daniel.teleanu@umfcd.ro (D.M.T.); oana-aurelia.vladacenco@drd.umfcd.ro (O.V.); eugenia.roza@umfcd.ro (E.R.); raluca.teleanu@umfcd.ro (R.I.T.) – name: 5 Department of Pediatric Neurology, “Dr. Victor Gomoiu” Children’s Hospital, 022102 Bucharest, Romania – name: 8 ICUB—Research Institute of University of Bucharest, University of Bucharest, 050657 Bucharest, Romania
Author_xml	– sequence: 1 givenname: Daniel Mihai surname: Teleanu fullname: Teleanu, Daniel Mihai – sequence: 2 givenname: Adelina-Gabriela orcidid: 0000-0001-8968-504X surname: Niculescu fullname: Niculescu, Adelina-Gabriela – sequence: 3 givenname: Iulia Ioana surname: Lungu fullname: Lungu, Iulia Ioana – sequence: 4 givenname: Crina Ioana surname: Radu fullname: Radu, Crina Ioana – sequence: 5 givenname: Oana surname: Vladâcenco fullname: Vladâcenco, Oana – sequence: 6 givenname: Eugenia surname: Roza fullname: Roza, Eugenia – sequence: 7 givenname: Bogdan surname: Costăchescu fullname: Costăchescu, Bogdan – sequence: 8 givenname: Alexandru Mihai orcidid: 0000-0003-3036-094X surname: Grumezescu fullname: Grumezescu, Alexandru Mihai – sequence: 9 givenname: Raluca Ioana surname: Teleanu fullname: Teleanu, Raluca Ioana
BackLink	https://www.ncbi.nlm.nih.gov/pubmed/35682615$$D View this record in MEDLINE/PubMed
BookMark	eNptkctLxDAQxoMo6q7ePEvBi4ddzaNpm4sgvkFc8HEOaTPVLG2iSbvqf2_X7soqnibM_L6PLzMDtG6dBYT2CD5iTOBjM60DZYRwwbI1tE1iSscYJ-n6ynsLDUKYYkwZ5WITbTGeZDQhfBvdn9poMgM_M_AeuTKafBitGjOD6KHxEMIouoPWO2PLStV1N3F2FCmr-7aGZ7Dge8G5CaAChB20UaoqwO6iDtHT5cXj2fX4dnJ1c3Z6Oy7iNGvGSghQsSakIFQVOsOlTnkeE1WqmGLGaYKFYIySPE2FxlpTTnKqRFqCYpgSNkQnve9rm9egC7CNV5V89aZW_lM6ZeTviTUv8tnNpCAZTjjrDA4XBt69tRAaWZtQQFUpC64NkiYpTwgmHHfowR906lpvu-_NqZglaSbmifZXE_1EWa67A2gPFN6F4KGUhWm-l9oFNJUkWM5vKldv2olGf0RL33_xLyJRozw
CitedBy_id	crossref_primary_10_1016_j_intimp_2024_112646 crossref_primary_10_1080_1028415X_2024_2352195 crossref_primary_10_1016_j_jpha_2024_101146 crossref_primary_10_1186_s12882_025_04276_z crossref_primary_10_1016_j_brainresbull_2025_111382 crossref_primary_10_1016_j_heliyon_2024_e24759 crossref_primary_10_1017_neu_2024_55 crossref_primary_10_3390_md23030094 crossref_primary_10_1016_j_neuropharm_2023_109706 crossref_primary_10_3389_fneur_2023_1158366 crossref_primary_10_1007_s10048_025_00801_2 crossref_primary_10_3390_app14114548 crossref_primary_10_3389_fnagi_2025_1670175 crossref_primary_10_31083_JIN39656 crossref_primary_10_3389_fnagi_2025_1568002 crossref_primary_10_2174_0115665240294605240426123650 crossref_primary_10_3390_antibiotics12111608 crossref_primary_10_3390_ijms252313076 crossref_primary_10_1002_imo2_33 crossref_primary_10_1016_j_jneuroim_2024_578518 crossref_primary_10_3390_ijms25020889 crossref_primary_10_1002_agm2_12284 crossref_primary_10_1016_j_micres_2024_127914 crossref_primary_10_1016_j_jff_2024_106003 crossref_primary_10_1016_j_theriogenology_2023_12_020 crossref_primary_10_1007_s12035_024_04062_2 crossref_primary_10_1007_s13273_025_00565_8 crossref_primary_10_1016_j_archger_2024_105739 crossref_primary_10_3390_chemistry7050141 crossref_primary_10_3390_brainsci14090876 crossref_primary_10_1186_s12951_024_03055_6 crossref_primary_10_3390_antiox14091066 crossref_primary_10_3390_app15063409 crossref_primary_10_1007_s12013_024_01292_y crossref_primary_10_3390_ijms26157079 crossref_primary_10_3389_fnins_2022_943400 crossref_primary_10_1111_cns_70464 crossref_primary_10_1096_fj_202302408R crossref_primary_10_3390_molecules29010233 crossref_primary_10_3390_ph18010002 crossref_primary_10_1007_s12672_025_02159_1 crossref_primary_10_3390_ijms26083658 crossref_primary_10_1038_s41589_024_01721_2 crossref_primary_10_1002_fsn3_3533 crossref_primary_10_1016_j_steroids_2024_109528 crossref_primary_10_3390_ph18060831 crossref_primary_10_1186_s40035_024_00459_0 crossref_primary_10_3928_23258160_20250326_02 crossref_primary_10_1016_j_carbpol_2025_123960 crossref_primary_10_1186_s40035_023_00341_5 crossref_primary_10_1093_braincomms_fcaf263 crossref_primary_10_3390_ijms24108874 crossref_primary_10_3390_antiox13070813 crossref_primary_10_1007_s10571_025_01563_z crossref_primary_10_1155_2023_8494176 crossref_primary_10_3390_molecules30092033 crossref_primary_10_2147_JIR_S478683 crossref_primary_10_1111_1750_3841_70230 crossref_primary_10_3390_ph18010133 crossref_primary_10_3390_biom15020172 crossref_primary_10_1016_j_jafr_2025_102272 crossref_primary_10_1007_s13577_024_01086_7 crossref_primary_10_3390_antiox14050531 crossref_primary_10_3390_ijms25053010 crossref_primary_10_1016_j_foodchem_2024_142538 crossref_primary_10_3390_foods14152678 crossref_primary_10_1016_j_bbr_2025_115840 crossref_primary_10_1007_s11064_025_04461_4 crossref_primary_10_1002_ibra_12126 crossref_primary_10_1007_s12013_025_01824_0 crossref_primary_10_3389_fnagi_2024_1357070 crossref_primary_10_3390_nu16203570 crossref_primary_10_3390_ijms25136928 crossref_primary_10_1093_ijnp_pyad063 crossref_primary_10_2147_DDDT_S534706 crossref_primary_10_1016_j_toxicon_2025_108568 crossref_primary_10_1016_j_intimp_2023_111471 crossref_primary_10_1016_j_wneu_2023_10_135 crossref_primary_10_1007_s44254_024_00078_y crossref_primary_10_1007_s11064_025_04475_y crossref_primary_10_23736_S0026_4806_25_09695_8 crossref_primary_10_1016_j_arr_2024_102298 crossref_primary_10_1021_acs_est_5c03968 crossref_primary_10_3390_md23010049 crossref_primary_10_2147_DNND_S452009 crossref_primary_10_1016_j_ctim_2024_103123 crossref_primary_10_3390_ijms252111344 crossref_primary_10_2147_DDDT_S494555 crossref_primary_10_3390_antiox13121493 crossref_primary_10_1007_s12668_025_02082_3 crossref_primary_10_3389_fphar_2025_1666082 crossref_primary_10_3390_toxics10080413 crossref_primary_10_1002_slct_202403725 crossref_primary_10_12677_pi_2024_135052 crossref_primary_10_3390_ijms25147811 crossref_primary_10_3390_nano14242018 crossref_primary_10_3390_ph18030382 crossref_primary_10_1080_01616412_2025_2559431 crossref_primary_10_1016_j_fbp_2025_07_019 crossref_primary_10_1007_s11064_025_04364_4 crossref_primary_10_3389_fneur_2023_1149963 crossref_primary_10_3390_ijms26136116 crossref_primary_10_3389_fphar_2025_1529194 crossref_primary_10_4274_balkanmedj_galenos_2024_2024_4_119 crossref_primary_10_3389_fphar_2023_1265571 crossref_primary_10_1177_11786388241253436 crossref_primary_10_3390_toxics13050347 crossref_primary_10_1016_j_chmed_2025_09_005 crossref_primary_10_1016_j_expneurol_2025_115419 crossref_primary_10_3390_life15081308 crossref_primary_10_3389_fimmu_2025_1532318 crossref_primary_10_1002_tox_24035 crossref_primary_10_1016_j_rbmo_2025_104873 crossref_primary_10_1016_j_parkreldis_2024_107017 crossref_primary_10_3390_antiox13121462 crossref_primary_10_5409_wjcp_v13_i2_92737 crossref_primary_10_1186_s12974_024_03272_8 crossref_primary_10_1007_s10787_023_01320_y crossref_primary_10_1016_j_jff_2025_106790 crossref_primary_10_1016_j_jstrokecerebrovasdis_2025_108373 crossref_primary_10_1155_jt_9317271 crossref_primary_10_1016_j_jep_2023_117275 crossref_primary_10_21926_obm_neurobiol_2404254 crossref_primary_10_1007_s10787_023_01388_6 crossref_primary_10_1016_j_phanu_2024_100399 crossref_primary_10_3390_nu15173799 crossref_primary_10_1016_j_neurot_2025_e00627 crossref_primary_10_3389_fnins_2023_1197094 crossref_primary_10_3390_medicina61071296 crossref_primary_10_3390_molecules28052176 crossref_primary_10_1007_s10517_024_06218_5 crossref_primary_10_1016_j_pnpbp_2025_111375 crossref_primary_10_1186_s41983_025_00957_6 crossref_primary_10_3390_antiox14040413 crossref_primary_10_3389_fnut_2025_1663647 crossref_primary_10_1042_BSR20241102 crossref_primary_10_3389_fncel_2023_1105247 crossref_primary_10_3390_pharmaceutics15051370 crossref_primary_10_3390_ijms231810572 crossref_primary_10_1016_j_ejmech_2023_115695 crossref_primary_10_3389_fvets_2024_1468520 crossref_primary_10_1016_j_neuropharm_2025_110461 crossref_primary_10_1016_j_freeradbiomed_2025_06_035 crossref_primary_10_3390_ijms26083587 crossref_primary_10_3390_biom15091345 crossref_primary_10_1007_s12035_024_04368_1 crossref_primary_10_3390_antiox14040441 crossref_primary_10_1016_j_ijbiomac_2025_143382 crossref_primary_10_3390_md23070270 crossref_primary_10_1007_s13205_025_04468_2 crossref_primary_10_2147_JAA_S467774 crossref_primary_10_1007_s11357_023_00888_1 crossref_primary_10_1016_j_fbio_2024_105079 crossref_primary_10_1093_toxres_tfaf111 crossref_primary_10_1007_s12035_025_04762_3 crossref_primary_10_1007_s00011_023_01790_4 crossref_primary_10_1007_s12640_022_00631_2 crossref_primary_10_31083_FBL25551 crossref_primary_10_1016_j_brainres_2025_149796 crossref_primary_10_1007_s00221_023_06757_9 crossref_primary_10_1007_s42250_023_00623_5 crossref_primary_10_3390_ijms25053060 crossref_primary_10_1007_s11064_023_04072_x crossref_primary_10_3390_molecules29235723 crossref_primary_10_3390_fermentation10070368 crossref_primary_10_1002_jbt_23547 crossref_primary_10_3390_biom13040678 crossref_primary_10_3390_cells13121072 crossref_primary_10_1007_s13205_025_04280_y crossref_primary_10_1016_j_intimp_2025_114954 crossref_primary_10_1016_j_cej_2025_165968 crossref_primary_10_1093_toxres_tfaf100 crossref_primary_10_51847_D7pD8ZUtCV crossref_primary_10_3389_fnmol_2023_1295240 crossref_primary_10_1016_j_brainres_2025_149568 crossref_primary_10_3389_fphar_2023_1264842 crossref_primary_10_1007_s12031_024_02192_9 crossref_primary_10_1007_s11064_025_04449_0 crossref_primary_10_1016_j_biocel_2025_106735 crossref_primary_10_3389_fncir_2023_1170395 crossref_primary_10_3390_biomedicines10071706 crossref_primary_10_1007_s11064_024_04255_0 crossref_primary_10_1007_s10787_024_01477_0 crossref_primary_10_1002_brb3_70766 crossref_primary_10_1016_j_jddst_2023_105067 crossref_primary_10_1186_s40360_025_00985_1 crossref_primary_10_1016_j_neulet_2024_137710 crossref_primary_10_1016_j_jep_2025_120327 crossref_primary_10_3390_foods12071554 crossref_primary_10_3390_antiox11102049 crossref_primary_10_1111_gbb_70011 crossref_primary_10_1016_j_arr_2024_102436 crossref_primary_10_1021_acschemneuro_5c00035 crossref_primary_10_1021_acschemneuro_5c00398 crossref_primary_10_3892_mmr_2025_13616 crossref_primary_10_1016_j_bbr_2023_114561 crossref_primary_10_1016_j_biocel_2023_106386 crossref_primary_10_3390_cimb46110777 crossref_primary_10_3390_antiox13101165 crossref_primary_10_1007_s11033_025_10840_5 crossref_primary_10_1016_j_bosn_2024_10_001 crossref_primary_10_1002_bab_2587 crossref_primary_10_1002_slct_202501590 crossref_primary_10_3390_antiox14040457 crossref_primary_10_1007_s11033_024_09771_4 crossref_primary_10_3390_pharmaceutics16081068 crossref_primary_10_1007_s11011_023_01193_8 crossref_primary_10_3390_ijms26062505 crossref_primary_10_1021_acsbiomaterials_4c02366 crossref_primary_10_2147_DDDT_S482510 crossref_primary_10_1002_cbdv_202500983 crossref_primary_10_1186_s13578_025_01418_6 crossref_primary_10_1038_s41398_024_03222_1 crossref_primary_10_1007_s10565_023_09820_x crossref_primary_10_3390_catal15010037 crossref_primary_10_1016_j_lfs_2023_122045 crossref_primary_10_3390_cells12111486 crossref_primary_10_1186_s40035_024_00435_8 crossref_primary_10_1007_s11011_024_01364_1 crossref_primary_10_3390_nano12142337 crossref_primary_10_1016_j_bcp_2024_116182 crossref_primary_10_3389_fddev_2023_1247162 crossref_primary_10_1007_s10528_025_11155_7 crossref_primary_10_1089_ars_2022_0174 crossref_primary_10_1177_20451253231195274 crossref_primary_10_3390_molecules28186629 crossref_primary_10_1080_01932691_2024_2431086 crossref_primary_10_3389_fnins_2025_1560344 crossref_primary_10_3390_medicina61081462 crossref_primary_10_2478_amma_2025_0018 crossref_primary_10_3390_ijms232012289 crossref_primary_10_1080_15287394_2025_2560022 crossref_primary_10_1016_j_snb_2025_137955 crossref_primary_10_11002_fsp_2025_32_2_344 crossref_primary_10_3389_fnut_2024_1371691 crossref_primary_10_1002_fsn3_70079 crossref_primary_10_1002_tox_24467 crossref_primary_10_1016_j_taap_2025_117570 crossref_primary_10_3390_ma18184302 crossref_primary_10_1016_j_bcp_2024_116174 crossref_primary_10_1007_s12011_023_03576_5 crossref_primary_10_1016_j_biopha_2025_117969 crossref_primary_10_1016_j_biopha_2024_117588 crossref_primary_10_1038_s41419_024_06807_2 crossref_primary_10_1016_j_nxmate_2024_100336 crossref_primary_10_3389_fneur_2023_1303111 crossref_primary_10_1002_cbdv_202402208 crossref_primary_10_2174_0118715273355336250226055826 crossref_primary_10_1088_1748_605X_addb1d crossref_primary_10_1002_ptr_8335 crossref_primary_10_3390_md21050261 crossref_primary_10_1155_2024_5514265 crossref_primary_10_3390_cimb47070538 crossref_primary_10_1016_j_neubiorev_2025_106159 crossref_primary_10_1080_14786419_2025_2547018 crossref_primary_10_1016_j_bpc_2023_107171 crossref_primary_10_1080_27697061_2025_2496489 crossref_primary_10_1016_j_polymertesting_2022_107822 crossref_primary_10_1093_toxres_tfae080 crossref_primary_10_1002_open_202400290 crossref_primary_10_1016_j_fct_2025_115261 crossref_primary_10_3389_fncel_2025_1575022 crossref_primary_10_3390_cells13040355 crossref_primary_10_1016_j_jpet_2025_103658 crossref_primary_10_3390_ijms241512008 crossref_primary_10_1016_j_ejphar_2025_177409 crossref_primary_10_1007_s43440_024_00602_8 crossref_primary_10_3390_ijms241210366 crossref_primary_10_1016_j_jff_2025_106717 crossref_primary_10_1016_j_ejmech_2023_116013 crossref_primary_10_3390_antiox12020225 crossref_primary_10_1167_iovs_66_5_31 crossref_primary_10_1080_15287394_2025_2538591 crossref_primary_10_1016_j_jphotobiol_2025_113104 crossref_primary_10_1016_j_freeradbiomed_2024_12_003 crossref_primary_10_1016_j_ijbiomac_2023_125787 crossref_primary_10_3390_ijms241512372 crossref_primary_10_1016_j_jad_2024_12_023 crossref_primary_10_3390_antiox14080929 crossref_primary_10_1016_j_apsb_2024_10_004 crossref_primary_10_3390_jof10020144 crossref_primary_10_1186_s12906_024_04579_y crossref_primary_10_3390_antiox13111396 crossref_primary_10_3390_ijms26115177 crossref_primary_10_1016_j_ijpharm_2024_125021 crossref_primary_10_3390_biom15050670 crossref_primary_10_3390_antiox13040393 crossref_primary_10_1021_acschemneuro_4c00205 crossref_primary_10_1016_j_jep_2024_117813 crossref_primary_10_1007_s12035_024_04409_9 crossref_primary_10_1016_j_neuroscience_2025_08_051 crossref_primary_10_3390_antiox14070818 crossref_primary_10_1128_msphere_00343_25 crossref_primary_10_1016_j_tcb_2025_07_005 crossref_primary_10_1155_2024_5594386 crossref_primary_10_1016_j_molstruc_2025_142184 crossref_primary_10_1016_j_jep_2025_120271 crossref_primary_10_1186_s12974_023_02950_3 crossref_primary_10_3390_cimb47060417 crossref_primary_10_3390_ph17060763 crossref_primary_10_1007_s40495_024_00365_z crossref_primary_10_3389_fphar_2025_1611733 crossref_primary_10_1002_syn_22301 crossref_primary_10_1016_j_npep_2025_102521 crossref_primary_10_3390_antiox12081525 crossref_primary_10_1016_j_phymed_2023_155304 crossref_primary_10_1016_j_bioactmat_2024_10_017 crossref_primary_10_1016_j_heliyon_2024_e36079 crossref_primary_10_1039_D3FO00129F crossref_primary_10_3390_metabo13030438 crossref_primary_10_1007_s11626_023_00759_1 crossref_primary_10_1016_j_lssr_2025_07_001 crossref_primary_10_3390_brainsci13111564 crossref_primary_10_1007_s11357_024_01231_y crossref_primary_10_1021_acsabm_5c00096 crossref_primary_10_1016_j_bcp_2025_117362 crossref_primary_10_3390_ijms26167795 crossref_primary_10_1016_j_vesic_2025_100071 crossref_primary_10_1089_ars_2024_0793 crossref_primary_10_1016_j_npep_2025_102534 crossref_primary_10_3390_pharmaceutics17060707 crossref_primary_10_1007_s11064_024_04177_x crossref_primary_10_3390_nu15173821 crossref_primary_10_3390_ijms26146627 crossref_primary_10_1007_s10068_025_01914_y crossref_primary_10_1016_j_apsb_2024_05_012 crossref_primary_10_1016_j_jns_2024_122889 crossref_primary_10_3389_fimmu_2025_1494114 crossref_primary_10_3390_ijms26146881 crossref_primary_10_1007_s11064_024_04308_4 crossref_primary_10_3390_jcm14020386 crossref_primary_10_1016_j_ccr_2023_215407 crossref_primary_10_3390_biomedicines13061464 crossref_primary_10_1186_s12964_024_01613_x crossref_primary_10_3390_horticulturae10010029 crossref_primary_10_1080_10408347_2023_2255901 crossref_primary_10_1016_j_heliyon_2024_e29424 crossref_primary_10_1016_j_bbrc_2024_150333 crossref_primary_10_3389_abp_2025_14164 crossref_primary_10_3390_molecules28217349 crossref_primary_10_1039_D4FO06458E crossref_primary_10_1007_s11172_024_4485_2 crossref_primary_10_3390_bios15050315 crossref_primary_10_1016_j_bcp_2023_115717 crossref_primary_10_1038_s41598_024_80102_0 crossref_primary_10_3390_ijms24098368 crossref_primary_10_1016_j_ejps_2023_106687 crossref_primary_10_1002_jnr_25253 crossref_primary_10_3390_ijms241310776 crossref_primary_10_3390_pharmaceutics17091134 crossref_primary_10_3390_antiox13050547 crossref_primary_10_1016_j_biomaterials_2025_123654 crossref_primary_10_1080_17582024_2025_2510175 crossref_primary_10_3390_nu15143189 crossref_primary_10_1016_j_molmed_2024_04_010 crossref_primary_10_7759_cureus_90042 crossref_primary_10_1007_s42452_025_06915_4 crossref_primary_10_52965_001c_125267 crossref_primary_10_1002_mco2_674 crossref_primary_10_13005_bpj_2655 crossref_primary_10_1039_D4FO02167C crossref_primary_10_3390_ijms25105466 crossref_primary_10_1016_j_jtcme_2024_02_002 crossref_primary_10_3389_fncel_2025_1590002 crossref_primary_10_1038_s41598_025_06118_2 crossref_primary_10_1007_s10462_024_11087_5 crossref_primary_10_3390_nu16071004 crossref_primary_10_3390_nano14231908 crossref_primary_10_1080_17582024_2025_2527543 crossref_primary_10_1007_s12035_024_04471_3 crossref_primary_10_3389_fnins_2024_1347320 crossref_primary_10_1016_j_ijbiomac_2025_140221 crossref_primary_10_3390_ani15131847 crossref_primary_10_1016_j_jff_2023_105764 crossref_primary_10_1111_bcpt_14011 crossref_primary_10_1111_bcpt_14010 crossref_primary_10_3390_antiox14070854 crossref_primary_10_1007_s12272_023_01484_9 crossref_primary_10_3892_ijmm_2025_5578 crossref_primary_10_1016_j_bioorg_2025_108585 crossref_primary_10_3389_fnagi_2024_1389454 crossref_primary_10_1016_j_intimp_2023_109727 crossref_primary_10_3390_antiox14020121 crossref_primary_10_1002_ffj_3871 crossref_primary_10_3389_fphar_2024_1506944 crossref_primary_10_1007_s41105_025_00582_z crossref_primary_10_1016_j_arr_2024_102600 crossref_primary_10_1007_s10072_023_07259_w crossref_primary_10_1016_j_jff_2023_105655 crossref_primary_10_1007_s43440_024_00610_8 crossref_primary_10_1016_j_ecoenv_2025_118960 crossref_primary_10_1016_j_jep_2023_116769 crossref_primary_10_1002_iid3_1345 crossref_primary_10_1007_s40820_025_01829_7 crossref_primary_10_1016_j_fsi_2025_110126 crossref_primary_10_3389_fvets_2024_1405541 crossref_primary_10_3390_antiox12101883 crossref_primary_10_1007_s44446_025_00026_2 crossref_primary_10_1016_j_bbr_2023_114763 crossref_primary_10_3389_fcell_2025_1626938 crossref_primary_10_1007_s12264_025_01439_8 crossref_primary_10_1042_BST20253067 crossref_primary_10_14814_phy2_15964 crossref_primary_10_1016_j_prenap_2025_100353 crossref_primary_10_3390_molecules30153158 crossref_primary_10_1038_s41598_024_51728_x crossref_primary_10_1016_j_ejphar_2024_177090 crossref_primary_10_1021_acschemneuro_4c00742 crossref_primary_10_1016_j_neuroimage_2025_121338 crossref_primary_10_3390_ijms232112774 crossref_primary_10_3390_antiox12091660 crossref_primary_10_3389_fnmol_2024_1441575 crossref_primary_10_3390_chemistry6060093 crossref_primary_10_31083_j_fbl2810252 crossref_primary_10_1080_09540105_2024_2434457 crossref_primary_10_1053_j_semnuclmed_2025_03_008 crossref_primary_10_1016_j_ijbiomac_2024_130473 crossref_primary_10_1016_j_brainres_2024_149099 crossref_primary_10_3390_ijms26135957 crossref_primary_10_1016_j_ijbiomac_2025_144936 crossref_primary_10_1007_s12223_025_01277_1 crossref_primary_10_1016_j_phytochem_2025_114566 crossref_primary_10_3390_agronomy14050999 crossref_primary_10_3390_antiox14070840 crossref_primary_10_1007_s11033_024_09905_8 crossref_primary_10_1016_j_jand_2025_03_001 crossref_primary_10_1016_j_heliyon_2023_e21800 crossref_primary_10_1177_15353702231222027 crossref_primary_10_1186_s12986_025_00902_7 crossref_primary_10_3390_nu17030391 crossref_primary_10_1080_17582024_2025_2520707 crossref_primary_10_1016_j_ejphar_2025_178154 crossref_primary_10_1016_j_fbio_2024_105631 crossref_primary_10_1007_s10854_024_11950_9 crossref_primary_10_1016_j_jconrel_2024_11_060 crossref_primary_10_3390_antiox12071325 crossref_primary_10_1016_j_biopha_2023_115512 crossref_primary_10_3390_ijms24087300 crossref_primary_10_1016_j_virol_2025_110658 crossref_primary_10_3389_fnhum_2025_1614132 crossref_primary_10_3892_ijmm_2024_5371 crossref_primary_10_3390_ijms25137304 crossref_primary_10_1016_j_jhazmat_2023_133219 crossref_primary_10_1038_s41593_024_01753_w crossref_primary_10_1111_cns_70191 crossref_primary_10_3390_antiox13091034 crossref_primary_10_1016_j_neuro_2024_06_015 crossref_primary_10_1186_s12951_024_02428_1 crossref_primary_10_3390_ijms26031130 crossref_primary_10_1016_j_brainresbull_2024_111039 crossref_primary_10_1016_j_intimp_2025_114399 crossref_primary_10_3390_foods13233909 crossref_primary_10_3390_ijms26052050 crossref_primary_10_2174_0113816128344629250115074105 crossref_primary_10_1080_02640414_2024_2433902 crossref_primary_10_3389_fneur_2025_1555411 crossref_primary_10_3389_fphys_2024_1320086 crossref_primary_10_3390_md23090338 crossref_primary_10_1016_j_ejmech_2023_115998 crossref_primary_10_1007_s11064_022_03751_5 crossref_primary_10_1016_j_molliq_2025_127938 crossref_primary_10_3390_antiox12071460 crossref_primary_10_3390_nu16172882 crossref_primary_10_1002_cbf_70073 crossref_primary_10_3389_fphar_2024_1372110 crossref_primary_10_3389_fphar_2024_1397332 crossref_primary_10_3389_fcimb_2023_1159771 crossref_primary_10_3390_dna5020017 crossref_primary_10_1002_fsn3_70522 crossref_primary_10_1097_MD_0000000000040141 crossref_primary_10_14336_AD_2025_0530 crossref_primary_10_1016_j_jatmed_2024_04_002 crossref_primary_10_1016_j_intimp_2025_114363 crossref_primary_10_1016_j_bmc_2024_118014 crossref_primary_10_1016_j_expneurol_2023_114432 crossref_primary_10_1016_j_chemosphere_2024_143180 crossref_primary_10_1093_schbul_sbaf131 crossref_primary_10_1111_psyg_12900 crossref_primary_10_4103_NRR_NRR_D_23_01566 crossref_primary_10_4162_nrp_2023_17_5_899 crossref_primary_10_3390_molecules30020266 crossref_primary_10_1002_advs_202307971 crossref_primary_10_1002_npr2_12445 crossref_primary_10_1016_j_aquatox_2024_106902 crossref_primary_10_1016_j_biopha_2025_118114 crossref_primary_10_3389_fncel_2022_988759 crossref_primary_10_1016_j_ijbiomac_2025_146088 crossref_primary_10_1016_j_neuroscience_2025_06_037 crossref_primary_10_3390_molecules29204799 crossref_primary_10_3390_molecules29225354 crossref_primary_10_37349_ent_2025_1004105 crossref_primary_10_1186_s12964_024_01965_4 crossref_primary_10_37349_ent_2025_1004104 crossref_primary_10_1007_s10787_022_01101_z crossref_primary_10_2147_NDT_S479757 crossref_primary_10_3390_nu17172884 crossref_primary_10_3390_biomass5010011 crossref_primary_10_1016_j_foodchem_2025_145704 crossref_primary_10_2174_0122117385271262231114075737 crossref_primary_10_1016_j_jbiotec_2022_09_009 crossref_primary_10_1016_j_brainresbull_2025_111191 crossref_primary_10_1016_j_freeradbiomed_2025_03_032 crossref_primary_10_4236_aar_2025_144007 crossref_primary_10_1016_j_jneuroim_2025_578556 crossref_primary_10_1016_j_ijpx_2025_100361 crossref_primary_10_1016_j_scitotenv_2024_170670 crossref_primary_10_1097_MS9_0000000000003425 crossref_primary_10_1007_s11033_022_08060_2 crossref_primary_10_3390_nu17172835 crossref_primary_10_1016_j_exger_2024_112539 crossref_primary_10_3390_molecules30051061 crossref_primary_10_3389_fendo_2023_1134025 crossref_primary_10_3390_plants11152066 crossref_primary_10_1002_jnr_25228 crossref_primary_10_3389_fnagi_2022_986127 crossref_primary_10_3390_md23080317 crossref_primary_10_1016_j_ijbiomac_2025_141715 crossref_primary_10_3389_fncel_2024_1496163 crossref_primary_10_1016_j_jad_2025_119999 crossref_primary_10_1007_s12035_023_03864_0 crossref_primary_10_1007_s12013_024_01607_z crossref_primary_10_3390_ijms24010442 crossref_primary_10_1016_j_brainres_2024_148821 crossref_primary_10_3389_fnmol_2023_1197853 crossref_primary_10_3390_nu15173855 crossref_primary_10_3390_cells14070511 crossref_primary_10_3390_ph18040486 crossref_primary_10_1155_ijh_8880889 crossref_primary_10_1186_s10020_025_01126_4 crossref_primary_10_3390_ijms232113246 crossref_primary_10_1371_journal_pone_0312828 crossref_primary_10_3390_ijms252413448 crossref_primary_10_1186_s42269_023_01047_4 crossref_primary_10_3390_ijms25052698 crossref_primary_10_1002_mco2_70268 crossref_primary_10_1096_fba_2025_00093 crossref_primary_10_2174_0125899775298987240528050110 crossref_primary_10_3390_ijms26031205 crossref_primary_10_1007_s11011_025_01699_3 crossref_primary_10_1007_s12602_024_10426_w crossref_primary_10_1016_j_tips_2023_11_004 crossref_primary_10_3390_ijms26052366 crossref_primary_10_1038_s41598_024_80479_y crossref_primary_10_16919_bozoktip_1716368 crossref_primary_10_1515_revneuro_2023_0091 crossref_primary_10_1007_s10787_025_01641_0 crossref_primary_10_1038_s41398_024_03075_8 crossref_primary_10_1016_j_intimp_2023_109698 crossref_primary_10_3389_fphar_2024_1446304 crossref_primary_10_1002_brx2_70008 crossref_primary_10_4103_NRR_NRR_D_24_01371 crossref_primary_10_1007_s11033_024_09984_7 crossref_primary_10_1007_s10753_025_02237_0 crossref_primary_10_1002_slct_202300895 crossref_primary_10_1016_j_bja_2025_02_039 crossref_primary_10_1007_s11356_023_28538_1 crossref_primary_10_1007_s11101_025_10123_8 crossref_primary_10_3390_antiox13060651 crossref_primary_10_3390_antiox14070796 crossref_primary_10_1016_j_neuroscience_2025_05_302 crossref_primary_10_1002_npr2_12523 crossref_primary_10_1097_MD_0000000000043725 crossref_primary_10_1016_j_bioorg_2025_108516 crossref_primary_10_1007_s11033_024_09558_7 crossref_primary_10_1007_s13258_024_01591_x crossref_primary_10_3390_vetsci11100470 crossref_primary_10_1265_ehpm_24_00126 crossref_primary_10_1007_s10753_025_02301_9 crossref_primary_10_1111_jcmm_18486 crossref_primary_10_3389_fnut_2025_1598588 crossref_primary_10_1016_j_jep_2025_120082 crossref_primary_10_3390_antiox13050508 crossref_primary_10_1002_advs_202306675
Cites_doi	10.3389/fphys.2018.00044 10.1016/j.sajb.2018.07.010 10.2174/1389450120666191112155654 10.3390/antiox9090901 10.2174/1570159X13666151030102718 10.3389/fnagi.2021.617588 10.3233/JAD-190863 10.1080/13880209.2016.1226356 10.1186/s12944-015-0145-8 10.1007/s00204-019-02538-y 10.3233/JHD-160205 10.1016/j.neuroscience.2022.01.026 10.33263/BRIAC106.71357151 10.1042/BJ20101695 10.1016/j.redox.2018.01.008 10.1002/jcb.26536 10.3389/fnmol.2018.00329 10.1111/acel.13031 10.3390/antiox10060827 10.1080/01616412.2016.1251711 10.1007/s12640-018-9989-9 10.3892/br.2016.630 10.18632/aging.202868 10.3389/fnins.2018.00010 10.1016/j.indcrop.2018.08.038 10.2147/CIA.S158513 10.3233/JAD-130722 10.3390/jcm11082265 10.1111/imm.12922 10.3389/fneur.2019.00148 10.1016/j.ctim.2019.102294 10.1038/s41467-018-03733-8 10.3389/fnins.2018.00721 10.1016/j.freeradbiomed.2018.10.396 10.3390/molecules24081583 10.1089/ars.2019.7762 10.14336/AD.2017.1018 10.3390/ijms20040879 10.3390/molecules23123305 10.1016/j.indcrop.2020.112089 10.3389/fphys.2018.00477 10.1016/j.lfs.2019.03.055 10.1002/cbdv.201700102 10.1007/978-1-4939-1071-7 10.1186/s12906-016-0998-z 10.3390/molecules26041107 10.1155/2012/823206 10.1007/s10529-021-03200-3 10.1016/j.freeradbiomed.2010.05.016 10.3390/nu9070659 10.33263/BRIAC115.1251612529 10.1038/s41583-019-0132-6 10.1038/nrd1330 10.3390/antiox9070577 10.1515/revneuro-2018-0080 10.1155/2019/9426867 10.3390/biom10010059 10.1016/j.phymed.2018.10.032 10.1002/jnr.24492 10.1007/978-1-60327-514-9 10.1016/j.redox.2017.10.014 10.1021/acsami.9b12319 10.1111/jphp.12424 10.33263/BRIAC106.71067119 10.3389/fnagi.2017.00168 10.33263/BRIAC106.66766687 10.1038/nrdp.2017.71 10.1002/stem.1932 10.1016/j.toxrep.2019.03.006 10.3389/fncel.2018.00114 10.31254/phyto.2019.8210 10.1186/s12987-020-00230-3 10.1007/s11064-011-0619-7 10.5607/en.2015.24.4.325 10.1016/j.indcrop.2019.112069 10.1155/2019/2105607 10.3389/fcell.2018.00132 10.33263/BRIAC116.1393413951 10.1016/j.brainres.2021.147444 10.1111/jfbc.12187 10.1007/978-3-319-28383-8_12 10.1002/1873-3468.12964 10.3389/fncel.2014.00131 10.1371/journal.pone.0190790 10.1155/2017/2525967 10.33263/BRIAC106.73297336 10.1016/j.sajb.2020.04.032 10.1016/j.biopha.2019.108673 10.3390/ijms23020907 10.1016/j.vaccine.2019.07.044 10.1016/j.yrtph.2016.06.024 10.1038/s41598-017-01402-2 10.1146/annurev-biochem-061516-044518 10.1002/stem.2651 10.1016/j.ynstr.2018.05.003
ContentType	Journal Article
Copyright	2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. 2022 by the authors. 2022
Copyright_xml	– notice: 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. – notice: 2022 by the authors. 2022
DBID	AAYXX CITATION CGR CUY CVF ECM EIF NPM 3V. 7X7 7XB 88E 8FI 8FJ 8FK 8G5 ABUWG AFKRA AZQEC BENPR CCPQU COVID DWQXO FYUFA GHDGH GNUQQ GUQSH K9. M0S M1P M2O MBDVC PHGZM PHGZT PIMPY PJZUB PKEHL PPXIY PQEST PQQKQ PQUKI PRINS Q9U 7X8 5PM
DOI	10.3390/ijms23115938
DatabaseName	CrossRef Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed ProQuest Central (Corporate) Health & Medical Collection ProQuest Central (purchase pre-March 2016) Medical Database (Alumni Edition) Hospital Premium Collection Hospital Premium Collection (Alumni Edition) ProQuest Central (Alumni) (purchase pre-March 2016) Research Library (Alumni) ProQuest Central (Alumni) ProQuest Central UK/Ireland ProQuest Central Essentials ProQuest Central ProQuest One Community College Coronavirus Research Database ProQuest Central Korea Health Research Premium Collection Health Research Premium Collection (Alumni) ProQuest Central Student ProQuest Research Library ProQuest Health & Medical Complete (Alumni) ProQuest Health & Medical Collection Medical Database Research Library Research Library (Corporate) ProQuest Central Premium ProQuest One Academic (New) Publicly Available Content Database ProQuest Health & Medical Research Collection ProQuest One Academic Middle East (New) ProQuest One Health & Nursing ProQuest One Academic Eastern Edition (DO NOT USE) ProQuest One Academic (retired) ProQuest One Academic UKI Edition ProQuest Central China ProQuest Central Basic MEDLINE - Academic PubMed Central (Full Participant titles)
DatabaseTitle	CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) Publicly Available Content Database Research Library Prep ProQuest Central Student ProQuest One Academic Middle East (New) ProQuest Central Essentials ProQuest Health & Medical Complete (Alumni) ProQuest Central (Alumni Edition) ProQuest One Community College ProQuest One Health & Nursing Research Library (Alumni Edition) ProQuest Central China ProQuest Central ProQuest Health & Medical Research Collection Health Research Premium Collection Health and Medicine Complete (Alumni Edition) ProQuest Central Korea Health & Medical Research Collection ProQuest Research Library ProQuest Central (New) ProQuest Medical Library (Alumni) ProQuest Central Basic ProQuest One Academic Eastern Edition Coronavirus Research Database ProQuest Hospital Collection Health Research Premium Collection (Alumni) ProQuest Hospital Collection (Alumni) ProQuest Health & Medical Complete ProQuest Medical Library ProQuest One Academic UKI Edition ProQuest One Academic ProQuest One Academic (New) ProQuest Central (Alumni) MEDLINE - Academic
DatabaseTitleList	CrossRef MEDLINE - Academic MEDLINE Publicly Available Content Database
Database_xml	– sequence: 1 dbid: NPM name: PubMed url: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: PIMPY name: Publicly Available Content Database url: http://search.proquest.com/publiccontent sourceTypes: Aggregation Database
DeliveryMethod	fulltext_linktorsrc
Discipline	Biology
EISSN	1422-0067
ExternalDocumentID	PMC9180653 35682615 10_3390_ijms23115938
Genre	Journal Article Review
GroupedDBID	--- 29J 2WC 53G 5GY 5VS 7X7 88E 8FE 8FG 8FH 8FI 8FJ 8G5 A8Z AADQD AAFWJ AAHBH AAYXX ABDBF ABUWG ACGFO ACIHN ACIWK ACPRK ACUHS ADBBV AEAQA AENEX AFFHD AFKRA AFZYC ALMA_UNASSIGNED_HOLDINGS AOIJS AZQEC BAWUL BCNDV BENPR BPHCQ BVXVI CCPQU CITATION CS3 D1I DIK DU5 DWQXO E3Z EBD EBS EJD ESX F5P FRP FYUFA GNUQQ GUQSH GX1 HH5 HMCUK HYE IAO IHR ITC KQ8 LK8 M1P M2O M48 MODMG O5R O5S OK1 OVT P2P PHGZM PHGZT PIMPY PJZUB PPXIY PQQKQ PROAC PSQYO RNS RPM TR2 TUS UKHRP ~8M 3V. ABJCF ALIPV BBNVY BHPHI CGR CUY CVF ECM EIF GROUPED_DOAJ HCIFZ KB. M7P M~E NPM PDBOC 7XB 8FK COVID ESTFP K9. MBDVC PKEHL PQEST PQUKI PRINS Q9U 7X8 PUEGO 5PM
ID	FETCH-LOGICAL-c478t-a99ea4d11c12acd80fd75b41afa42035260993321b779d0dd251b2a97fea30213
IEDL.DBID	BENPR
ISICitedReferencesCount	644
ISICitedReferencesURI	http://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=Summon&SrcAuth=ProQuest&DestLinkType=CitingArticles&DestApp=WOS_CPL&KeyUT=000808965900001&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D
ISSN	1422-0067 1661-6596
IngestDate	Tue Nov 04 02:02:55 EST 2025 Thu Oct 02 11:31:13 EDT 2025 Tue Oct 07 07:41:42 EDT 2025 Wed Feb 19 02:26:53 EST 2025 Tue Nov 18 21:07:11 EST 2025 Sat Nov 29 07:18:40 EST 2025
IsDoiOpenAccess	true
IsOpenAccess	true
IsPeerReviewed	true
IsScholarly	true
Issue	11
Keywords	neurodegenerative disease antioxidants neuroinflammation reactive oxidative species
Language	English
License	Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
LinkModel	DirectLink
MergedId	FETCHMERGED-LOGICAL-c478t-a99ea4d11c12acd80fd75b41afa42035260993321b779d0dd251b2a97fea30213
Notes	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 ObjectType-Review-3 content type line 23
ORCID	0000-0001-8968-504X 0000-0003-3036-094X
OpenAccessLink	https://www.proquest.com/docview/2674367891?pq-origsite=%requestingapplication%
PMID	35682615
PQID	2674367891
PQPubID	2032341
ParticipantIDs	pubmedcentral_primary_oai_pubmedcentral_nih_gov_9180653 proquest_miscellaneous_2675610150 proquest_journals_2674367891 pubmed_primary_35682615 crossref_citationtrail_10_3390_ijms23115938 crossref_primary_10_3390_ijms23115938
PublicationCentury	2000
PublicationDate	20220525
PublicationDateYYYYMMDD	2022-05-25
PublicationDate_xml	– month: 5 year: 2022 text: 20220525 day: 25
PublicationDecade	2020
PublicationPlace	Switzerland
PublicationPlace_xml	– name: Switzerland – name: Basel
PublicationTitle	International journal of molecular sciences
PublicationTitleAlternate	Int J Mol Sci
PublicationYear	2022
Publisher	MDPI AG MDPI
Publisher_xml	– name: MDPI AG – name: MDPI
References	Amanzadeh (ref_94) 2019; 30 Cenini (ref_123) 2019; 2019 Misrani (ref_9) 2021; 13 Zaplatic (ref_98) 2019; 224 ref_90 Cobley (ref_20) 2018; 15 Bernier (ref_92) 2018; 9 Zengin (ref_116) 2016; 10 Stephenson (ref_2) 2018; 154 ref_97 Duhan (ref_73) 2020; 10 Esmaili (ref_102) 2021; 11 Ayaz (ref_103) 2017; 9 ref_19 ref_18 McLimans (ref_80) 2019; 31 Ademosun (ref_108) 2016; 40 Avery (ref_16) 2011; 434 Cong (ref_68) 2019; 11 Islam (ref_59) 2017; 39 Sevindik (ref_119) 2016; 10 Aljadaan (ref_96) 2020; 10 Angelova (ref_45) 2018; 592 ref_25 Tamtaji (ref_95) 2020; 21 Cheignon (ref_42) 2018; 14 Hartl (ref_61) 2017; 86 Younus (ref_79) 2018; 12 Bahadori (ref_115) 2020; 145 Saxena (ref_78) 2022; 44 Hassine (ref_113) 2019; 120 ref_29 ref_28 ref_27 ref_26 Kadry (ref_6) 2020; 17 Bond (ref_33) 2018; 12 Nikolova (ref_121) 2016; 81 ref_70 Barnham (ref_7) 2004; 3 Ishola (ref_5) 2021; 11 Cassidy (ref_46) 2020; 49 Panahi (ref_72) 2019; 120 (ref_69) 2018; 12 Kazakov (ref_12) 2020; 10 Sriraksa (ref_99) 2012; 2012 Rahman (ref_22) 2020; 10 Abuhamdah (ref_105) 2015; 67 Liguori (ref_124) 2018; 13 ref_83 Elumalai (ref_93) 2016; 12 Postu (ref_110) 2019; 112 Liu (ref_10) 2018; 9 Shinto (ref_50) 2014; 38 ref_89 Zhao (ref_82) 2019; 37 Nikolova (ref_122) 2019; 6 Simunkova (ref_49) 2019; 93 Ward (ref_24) 2017; 7 Trist (ref_21) 2019; 18 Jamous (ref_109) 2018; 124 Zheng (ref_62) 2018; 11 ref_58 ref_57 Wang (ref_100) 2021; 13 ref_56 ref_55 ref_54 ref_53 ref_52 ref_51 Ozaslan (ref_107) 2020; 145 Ashrafi (ref_41) 2020; 10 Filograna (ref_76) 2016; 14 Adewale (ref_75) 2019; 8 Liu (ref_1) 2017; 2017 Kohoude (ref_106) 2017; 55 ref_63 Balogun (ref_14) 2021; 11 Tobore (ref_65) 2019; 97 Kim (ref_13) 2015; 24 Volkman (ref_3) 2017; 35 Ighodaro (ref_77) 2018; 54 Pollari (ref_34) 2014; 8 Kojima (ref_85) 2018; 9 Chen (ref_15) 2018; 6 Kumar (ref_67) 2016; 5 Bisht (ref_71) 2018; 9 Venkateshappa (ref_23) 2012; 37 Zhao (ref_88) 2019; 2019 Sadiki (ref_117) 2019; 56 ref_118 Selva (ref_11) 2018; 12 ref_36 Butterfield (ref_48) 2019; 20 ref_35 ref_31 ref_30 ref_112 Hardiman (ref_32) 2017; 3 Cioffi (ref_47) 2019; 72 Schirinzi (ref_87) 2019; 10 ref_39 ref_38 Ayaz (ref_111) 2015; 14 ref_37 Moghaddam (ref_60) 2021; 1762 Haney (ref_86) 2018; 128 Shefali (ref_17) 2021; 11 Sorolla (ref_66) 2010; 49 Bubacco (ref_81) 2018; 9 ref_104 Rahman (ref_43) 2021; 11 ref_40 ref_101 Yousefi (ref_74) 2021; 11 He (ref_91) 2015; 33 Huang (ref_44) 2016; 4 ref_8 Cutillas (ref_114) 2017; 14 Issa (ref_120) 2020; 132 Essa (ref_64) 2019; 35 ref_4 MacKenzie (ref_84) 2022; 487
References_xml	– volume: 9 start-page: 44 year: 2018 ident: ref_92 article-title: Coenzyme Q10 Supplementation in Aging and Disease publication-title: Front. Physiol. doi: 10.3389/fphys.2018.00044 – volume: 120 start-page: 253 year: 2019 ident: ref_113 article-title: Salvia officinalis essential oil: Chemical analysis and evaluation of anti-enzymatic and antioxidant bioactivities publication-title: S. Afr. J. Bot. doi: 10.1016/j.sajb.2018.07.010 – volume: 21 start-page: 509 year: 2020 ident: ref_95 article-title: The Therapeutic Potential of Quercetin in Parkinson’s Disease: Insights into its Molecular and Cellular Regulation publication-title: Curr. Drug Targets doi: 10.2174/1389450120666191112155654 – ident: ref_31 doi: 10.3390/antiox9090901 – volume: 14 start-page: 260 year: 2016 ident: ref_76 article-title: Anti-Oxidants in Parkinson’s Disease Therapy: A Critical Point of View publication-title: Curr. Neuropharmacol. doi: 10.2174/1570159X13666151030102718 – ident: ref_51 – volume: 13 start-page: 617588 year: 2021 ident: ref_9 article-title: Mitochondrial Dysfunction and Oxidative Stress in Alzheimer’s Disease publication-title: Front. Aging Neurosci. doi: 10.3389/fnagi.2021.617588 – volume: 72 start-page: 981 year: 2019 ident: ref_47 article-title: Molecular Mechanisms and Genetics of Oxidative Stress in Alzheimer’s Disease publication-title: J. Alzheimer’s Dis. doi: 10.3233/JAD-190863 – volume: 55 start-page: 33 year: 2017 ident: ref_106 article-title: Chemical composition and biological activities of extracts and essential oil of Boswellia dalzielii leaves publication-title: Pharm. Biol. doi: 10.1080/13880209.2016.1226356 – ident: ref_39 – volume: 11 start-page: 9432 year: 2021 ident: ref_14 article-title: Ameliorative Role of Plectranthus esculentus on 4-Vinylcyclohexene Monoepoxide-Induced Oxidative Stress in Drosophila melanogaster publication-title: Biointerface Res. Appl. Chem. – volume: 14 start-page: 141 year: 2015 ident: ref_111 article-title: Comparative chemical profiling, cholinesterase inhibitions and anti-radicals properties of essential oils from Polygonum hydropiper L: A Preliminary anti- Alzheimer’s study publication-title: Lipids Health Dis. doi: 10.1186/s12944-015-0145-8 – volume: 93 start-page: 2491 year: 2019 ident: ref_49 article-title: Management of oxidative stress and other pathologies in Alzheimer’s disease publication-title: Arch. Toxicol. doi: 10.1007/s00204-019-02538-y – volume: 5 start-page: 217 year: 2016 ident: ref_67 article-title: Oxidative Stress and Huntington’s Disease: The Good, The Bad, and The Ugly publication-title: J. Huntingt. Dis. doi: 10.3233/JHD-160205 – volume: 487 start-page: 47 year: 2022 ident: ref_84 article-title: Microglial Inflammation and Cognitive Dysfunction in Comorbid Rat Models of Striatal Ischemic Stroke and Alzheimer’s Disease: Effects of Antioxidant Catalase-SKL on Behavioral and Cellular Pathology publication-title: Neuroscience doi: 10.1016/j.neuroscience.2022.01.026 – volume: 10 start-page: 7135 year: 2020 ident: ref_22 article-title: Emerging Promise of Nanoparticle-Based Treatment for Parkinson’s disease publication-title: Biointerface Res. Appl. Chem. doi: 10.33263/BRIAC106.71357151 – volume: 434 start-page: 201 year: 2011 ident: ref_16 article-title: Molecular targets of oxidative stress publication-title: Biochem. J. doi: 10.1042/BJ20101695 – volume: 11 start-page: 9871 year: 2021 ident: ref_5 article-title: Molecular Docking Studies of Flavonoids from Andrographis paniculata as Potential Acetylcholinesterase, Butyrylcholinesterase and Monoamine Oxidase Inhibitors towards the Treatment of Neurodegenerative Diseases publication-title: Biointerface Res. Appl. Chem. – ident: ref_56 – volume: 15 start-page: 490 year: 2018 ident: ref_20 article-title: 13 reasons why the brain is susceptible to oxidative stress publication-title: Redox Biol. doi: 10.1016/j.redox.2018.01.008 – ident: ref_27 – volume: 120 start-page: 2742 year: 2019 ident: ref_72 article-title: Neuroprotective effects of antioxidants in the management of neurodegenerative disorders: A literature review publication-title: J. Cell. Biochem. doi: 10.1002/jcb.26536 – volume: 11 start-page: 329 year: 2018 ident: ref_62 article-title: A Mitochondria-Associated Oxidative Stress Perspective on Huntington’s Disease publication-title: Front. Mol. Neurosci. doi: 10.3389/fnmol.2018.00329 – volume: 18 start-page: e13031 year: 2019 ident: ref_21 article-title: Oxidative stress in the aging substantia nigra and the etiology of Parkinson’s disease publication-title: Aging Cell doi: 10.1111/acel.13031 – ident: ref_83 doi: 10.3390/antiox10060827 – volume: 39 start-page: 73 year: 2017 ident: ref_59 article-title: Oxidative stress and mitochondrial dysfunction-linked neurodegenerative disorders publication-title: Neurol. Res. doi: 10.1080/01616412.2016.1251711 – volume: 35 start-page: 739 year: 2019 ident: ref_64 article-title: Protective Effects of Antioxidants in Huntington’s Disease: An Extensive Review publication-title: Neurotox. Res. doi: 10.1007/s12640-018-9989-9 – volume: 4 start-page: 519 year: 2016 ident: ref_44 article-title: Role of oxidative stress in Alzheimer’s disease publication-title: Biomed. Rep. doi: 10.3892/br.2016.630 – ident: ref_28 – ident: ref_53 – ident: ref_30 – volume: 13 start-page: 11738 year: 2021 ident: ref_100 article-title: Administration of quercetin improves mitochondria quality control and protects the neurons in 6-OHDA-lesioned Parkinson’s disease models publication-title: Aging doi: 10.18632/aging.202868 – volume: 10 start-page: 4893 year: 2020 ident: ref_12 article-title: Interplay between antioxidant activity, health and disease publication-title: Biointerface Res. Appl. Chem. – volume: 12 start-page: 10 year: 2018 ident: ref_33 article-title: A Metadata Analysis of Oxidative Stress Etiology in Preclinical Amyotrophic Lateral Sclerosis: Benefits of Antioxidant Therapy publication-title: Front. Neurosci. doi: 10.3389/fnins.2018.00010 – volume: 124 start-page: 617 year: 2018 ident: ref_109 article-title: Chemical profile and bioactive properties of the essential oil isolated from Clinopodium serpyllifolium (M.Bieb.) Kuntze growing in Palestine publication-title: Ind. Crops Prod. doi: 10.1016/j.indcrop.2018.08.038 – volume: 13 start-page: 757 year: 2018 ident: ref_124 article-title: Oxidative stress, aging, and diseases publication-title: Clin. Interv. Aging doi: 10.2147/CIA.S158513 – volume: 38 start-page: 111 year: 2014 ident: ref_50 article-title: A randomized placebo-controlled pilot trial of omega-3 fatty acids and alpha lipoic acid in Alzheimer’s disease publication-title: J. Alzheimer’s Dis. doi: 10.3233/JAD-130722 – ident: ref_4 doi: 10.3390/jcm11082265 – volume: 154 start-page: 204 year: 2018 ident: ref_2 article-title: Inflammation in CNS neurodegenerative diseases publication-title: Immunology doi: 10.1111/imm.12922 – volume: 10 start-page: 148 year: 2019 ident: ref_87 article-title: Dietary Vitamin E as a Protective Factor for Parkinson’s Disease: Clinical and Experimental Evidence publication-title: Front. Neurol. doi: 10.3389/fneur.2019.00148 – volume: 49 start-page: 102294 year: 2020 ident: ref_46 article-title: Oxidative stress in alzheimer’s disease: A review on emergent natural polyphenolic therapeutics publication-title: Complementary Ther. Med. doi: 10.1016/j.ctim.2019.102294 – volume: 9 start-page: 1305 year: 2018 ident: ref_85 article-title: Designer exosomes produced by implanted cells intracerebrally deliver therapeutic cargo for Parkinson’s disease treatment publication-title: Nat. Commun. doi: 10.1038/s41467-018-03733-8 – volume: 12 start-page: 721 year: 2018 ident: ref_11 article-title: Neuroprotective Natural Molecules, from Food to Brain publication-title: Front. Neurosci. doi: 10.3389/fnins.2018.00721 – volume: 128 start-page: S18 year: 2018 ident: ref_86 article-title: P22—Extracellular Vesicles as Drug Delivery Vehicles for Potent Redox Enzyme Catalase to Treat Parkinson’s Disease publication-title: Free Radic. Biol. Med. doi: 10.1016/j.freeradbiomed.2018.10.396 – ident: ref_19 doi: 10.3390/molecules24081583 – volume: 31 start-page: 572 year: 2019 ident: ref_80 article-title: Is Cerebrospinal Fluid Superoxide Dismutase 1 a Biomarker of Tau But Not Amyloid-Induced Neurodegeneration in Alzheimer’s Disease? publication-title: Antioxid. Redox Signal. doi: 10.1089/ars.2019.7762 – volume: 9 start-page: 716 year: 2018 ident: ref_81 article-title: Superoxide Radical Dismutation as New Therapeutic Strategy in Parkinson’s Disease publication-title: Aging Dis. doi: 10.14336/AD.2017.1018 – ident: ref_89 doi: 10.3390/ijms20040879 – ident: ref_101 doi: 10.3390/molecules23123305 – ident: ref_25 – volume: 145 start-page: 112089 year: 2020 ident: ref_115 article-title: Essential oils of hedgenettles (Stachys inflata, S. lavandulifolia, and S. byzantina) have antioxidant, anti-Alzheimer, antidiabetic, and anti-obesity potential: A comparative study publication-title: Ind. Crops Prod. doi: 10.1016/j.indcrop.2020.112089 – volume: 9 start-page: 477 year: 2018 ident: ref_10 article-title: Role of ROS and Nutritional Antioxidants in Human Diseases publication-title: Front. Physiol. doi: 10.3389/fphys.2018.00477 – volume: 224 start-page: 109 year: 2019 ident: ref_98 article-title: Molecular mechanisms underlying protective role of quercetin in attenuating Alzheimer’s disease publication-title: Life Sci. doi: 10.1016/j.lfs.2019.03.055 – volume: 14 start-page: e1700102 year: 2017 ident: ref_114 article-title: Salvia officinalis L. Essential Oils from Spain: Determination of Composition, Antioxidant Capacity, Antienzymatic, and Antimicrobial Bioactivities publication-title: Chem. Biodivers. doi: 10.1002/cbdv.201700102 – ident: ref_70 doi: 10.1007/978-1-4939-1071-7 – ident: ref_112 doi: 10.1186/s12906-016-0998-z – ident: ref_104 doi: 10.3390/molecules26041107 – ident: ref_36 – volume: 2012 start-page: 823206 year: 2012 ident: ref_99 article-title: Cognitive-Enhancing Effect of Quercetin in a Rat Model of Parkinson’s Disease Induced by 6-Hydroxydopamine publication-title: Evid.-Based Complementary Altern. Med. doi: 10.1155/2012/823206 – volume: 44 start-page: 1 year: 2022 ident: ref_78 article-title: Superoxide dismutase as multipotent therapeutic antioxidant enzyme: Role in human diseases publication-title: Biotechnol. Lett. doi: 10.1007/s10529-021-03200-3 – volume: 49 start-page: 612 year: 2010 ident: ref_66 article-title: Protein oxidation in Huntington disease affects energy production and vitamin B6 metabolism publication-title: Free Radic. Biol. Med. doi: 10.1016/j.freeradbiomed.2010.05.016 – ident: ref_55 – ident: ref_90 doi: 10.3390/nu9070659 – ident: ref_26 – volume: 11 start-page: 12516 year: 2021 ident: ref_102 article-title: A Review on the Use of Essential Oil-Based Nanoformulations in Control of Mosquitoes publication-title: Biointerface Res. Appl. Chem. doi: 10.33263/BRIAC115.1251612529 – volume: 11 start-page: 10493 year: 2021 ident: ref_17 article-title: Phytomicrobiome Studies for Combating the Abiotic Stress publication-title: Biointerface Res. Appl. Chem. – volume: 10 start-page: 195 year: 2016 ident: ref_116 article-title: Antioxidant Potential and Inhibition of Key Enzymes Linked to Alzheimer’s Diseases and Diabetes Mellitus by Monoterpene-Rich Essential Oil from Sideritis galatica Bornm. Endemic to Turkey publication-title: Rec. Nat. Prod. – volume: 20 start-page: 148 year: 2019 ident: ref_48 article-title: Oxidative stress, dysfunctional glucose metabolism and Alzheimer disease publication-title: Nat. Rev. Neurosci. doi: 10.1038/s41583-019-0132-6 – volume: 3 start-page: 205 year: 2004 ident: ref_7 article-title: Neurodegenerative diseases and oxidative stress publication-title: Nat. Rev. Drug Discov. doi: 10.1038/nrd1330 – ident: ref_63 doi: 10.3390/antiox9070577 – ident: ref_35 – volume: 30 start-page: 555 year: 2019 ident: ref_94 article-title: Application of quercetin in neurological disorders: From nutrition to nanomedicine publication-title: Rev. Neurosci. doi: 10.1515/revneuro-2018-0080 – volume: 2019 start-page: 9426867 year: 2019 ident: ref_88 article-title: Benefits of Vitamins in the Treatment of Parkinson’s Disease publication-title: Oxidative Med. Cell. Longev. doi: 10.1155/2019/9426867 – ident: ref_58 – ident: ref_97 doi: 10.3390/biom10010059 – volume: 56 start-page: 57 year: 2019 ident: ref_117 article-title: Tetraclinis articulata essential oil mitigates cognitive deficits and brain oxidative stress in an Alzheimer’s disease amyloidosis model publication-title: Phytomedicine doi: 10.1016/j.phymed.2018.10.032 – volume: 11 start-page: 8686 year: 2021 ident: ref_43 article-title: Genome-Wide Integrative Analysis Reveals Common Molecular Signatures in Blood and Brain of Alzheimer’s Disease publication-title: Biointerface Res. Appl. Chem. – volume: 97 start-page: 1455 year: 2019 ident: ref_65 article-title: Towards a comprehensive understanding of the contributions of mitochondrial dysfunction and oxidative stress in the pathogenesis and pathophysiology of Huntington’s disease publication-title: J. Neurosci. Res. doi: 10.1002/jnr.24492 – ident: ref_52 – ident: ref_18 doi: 10.1007/978-1-60327-514-9 – volume: 14 start-page: 450 year: 2018 ident: ref_42 article-title: Oxidative stress and the amyloid beta peptide in Alzheimer’s disease publication-title: Redox Biol. doi: 10.1016/j.redox.2017.10.014 – volume: 11 start-page: 34725 year: 2019 ident: ref_68 article-title: Selenium Nanoparticles as an Efficient Nanomedicine for the Therapy of Huntington’s Disease publication-title: ACS Appl. Mater. Interfaces doi: 10.1021/acsami.9b12319 – volume: 67 start-page: 1306 year: 2015 ident: ref_105 article-title: Pharmacological and neuroprotective profile of an essential oil derived from leaves of Aloysia citrodora Palau publication-title: J. Pharm. Pharmacol. doi: 10.1111/jphp.12424 – volume: 10 start-page: 7106 year: 2020 ident: ref_41 article-title: New Candidate Delivery System for Alzheimer’s Disease: Deferoxamine Nanogels publication-title: Biointerface Res. Appl. Chem. doi: 10.33263/BRIAC106.71067119 – volume: 9 start-page: 168 year: 2017 ident: ref_103 article-title: Neuroprotective and Anti-Aging Potentials of Essential Oils from Aromatic and Medicinal Plants publication-title: Front. Aging Neurosci. doi: 10.3389/fnagi.2017.00168 – ident: ref_38 – volume: 10 start-page: 6676 year: 2020 ident: ref_73 article-title: Bioactive Lipids: Chemistry & Health Benefits publication-title: Biointerface Res. Appl. Chem. doi: 10.33263/BRIAC106.66766687 – volume: 3 start-page: 17071 year: 2017 ident: ref_32 article-title: Amyotrophic lateral sclerosis publication-title: Nat. Rev. Dis. Prim. doi: 10.1038/nrdp.2017.71 – volume: 33 start-page: 1320 year: 2015 ident: ref_91 article-title: Vitamin C Facilitates Dopamine Neuron Differentiation in Fetal Midbrain Through TET1- and JMJD3-Dependent Epigenetic Control Manner publication-title: Stem Cells doi: 10.1002/stem.1932 – volume: 6 start-page: 267 year: 2019 ident: ref_122 article-title: Reducing oxidative toxicity of L-dopa in combination with two different antioxidants: An essential oil isolated from Rosa Damascena Mill., and vitamin C publication-title: Toxicol. Rep. doi: 10.1016/j.toxrep.2019.03.006 – volume: 12 start-page: 114 year: 2018 ident: ref_69 article-title: Effect of Chronic Oxidative Stress on Neuroinflammatory Response Mediated by CD4(+)T Cells in Neurodegenerative Diseases publication-title: Front. Cell. Neurosci. doi: 10.3389/fncel.2018.00114 – volume: 8 start-page: 75 year: 2019 ident: ref_75 article-title: Significance in the Treatment and Prevention of Neurodegenerative Diseases publication-title: J. Phytopharm. doi: 10.31254/phyto.2019.8210 – volume: 10 start-page: 503 year: 2016 ident: ref_119 article-title: Chemical Composition, Antioxidant Capacity, Acetyl-and Butyrylcholinesterase Inhibitory Activities of the Essential Oil of Thymus haussknechtii Velen publication-title: Rec. Nat. Prod. – volume: 17 start-page: 69 year: 2020 ident: ref_6 article-title: A blood–brain barrier overview on structure, function, impairment, and biomarkers of integrity publication-title: Fluids Barriers CNS doi: 10.1186/s12987-020-00230-3 – volume: 37 start-page: 358 year: 2012 ident: ref_23 article-title: Increased Oxidative Damage and Decreased Antioxidant Function in Aging Human Substantia Nigra Compared to Striatum: Implications for Parkinson’s Disease publication-title: Neurochem. Res. doi: 10.1007/s11064-011-0619-7 – volume: 12 start-page: 88 year: 2018 ident: ref_79 article-title: Therapeutic potentials of superoxide dismutase publication-title: Int. J. Health Sci. – volume: 24 start-page: 325 year: 2015 ident: ref_13 article-title: The Role of Oxidative Stress in Neurodegenerative Diseases publication-title: Exp. Neurobiol. doi: 10.5607/en.2015.24.4.325 – volume: 145 start-page: 112069 year: 2020 ident: ref_107 article-title: Anti-Alzheimer, anti-diabetic, skin-whitening, and antioxidant activities of the essential oil of Cinnamomum zeylanicum publication-title: Ind. Crops Prod. doi: 10.1016/j.indcrop.2019.112069 – volume: 2019 start-page: 2105607 year: 2019 ident: ref_123 article-title: Oxidative Stress in Neurodegenerative Diseases: From a Mitochondrial Point of View publication-title: Oxidative Med. Cell. Longev. doi: 10.1155/2019/2105607 – volume: 6 start-page: 132 year: 2018 ident: ref_15 article-title: Reactive Oxygen Species Formation in the Brain at Different Oxygen Levels: The Role of Hypoxia Inducible Factors publication-title: Front. Cell Dev. Biol. doi: 10.3389/fcell.2018.00132 – ident: ref_40 – volume: 11 start-page: 13934 year: 2021 ident: ref_74 article-title: Encapsulation Systems for Delivery of Flavonoids: A Review publication-title: Biointerface Res. Appl. Chem. doi: 10.33263/BRIAC116.1393413951 – ident: ref_37 – volume: 1762 start-page: 147444 year: 2021 ident: ref_60 article-title: Elderberry diet ameliorates motor function and prevents oxidative stress-induced cell death in rat models of Huntington disease publication-title: Brain Res. doi: 10.1016/j.brainres.2021.147444 – volume: 40 start-page: 53 year: 2016 ident: ref_108 article-title: Comparative study of chemical composition, in vitro inhibition of cholinergic and monoaminergic enzymes, and antioxidant potentials of essential oil from peels and seeds of sweet orange (Citrus sinensis [L.] Osbeck) Fruits publication-title: J. Food Biochem. doi: 10.1111/jfbc.12187 – volume: 12 start-page: 229 year: 2016 ident: ref_93 article-title: Role of Quercetin Benefits in Neurodegeneration publication-title: Adv. Neurobiol. doi: 10.1007/978-3-319-28383-8_12 – volume: 592 start-page: 692 year: 2018 ident: ref_45 article-title: Role of mitochondrial ROS in the brain: From physiology to neurodegeneration publication-title: FEBS Lett. doi: 10.1002/1873-3468.12964 – volume: 8 start-page: 131 year: 2014 ident: ref_34 article-title: The role of oxidative stress in degeneration of the neuromuscular junction in amyotrophic lateral sclerosis publication-title: Front. Cell. Neurosci. doi: 10.3389/fncel.2014.00131 – ident: ref_118 doi: 10.1371/journal.pone.0190790 – volume: 2017 start-page: 2525967 year: 2017 ident: ref_1 article-title: Oxidative Stress in Neurodegenerative Diseases: From Molecular Mechanisms to Clinical Applications publication-title: Oxidative Med. Cell. Longev. doi: 10.1155/2017/2525967 – ident: ref_29 – ident: ref_54 – volume: 10 start-page: 7329 year: 2020 ident: ref_96 article-title: Investigation of the Antioxidant and Antibacterial Activity of Novel Quercetin Derivatives publication-title: Biointerface Res. Appl. Chem. doi: 10.33263/BRIAC106.73297336 – volume: 132 start-page: 289 year: 2020 ident: ref_120 article-title: Neuroprotective effects of Pulicaria undulata essential oil in rotenone model of parkinson’s disease in rats: Insights into its anti-inflammatory and anti-oxidant effects publication-title: S. Afr. J. Bot. doi: 10.1016/j.sajb.2020.04.032 – volume: 112 start-page: 108673 year: 2019 ident: ref_110 article-title: Pinus halepensis essential oil attenuates the toxic Alzheimer’s amyloid beta (1-42)-induced memory impairment and oxidative stress in the rat hippocampus publication-title: Biomed. Pharmacother. doi: 10.1016/j.biopha.2019.108673 – ident: ref_8 doi: 10.3390/ijms23020907 – volume: 37 start-page: 4920 year: 2019 ident: ref_82 article-title: Therapeutic vaccines for amyotrophic lateral sclerosis directed against disease specific epitopes of superoxide dismutase 1 publication-title: Vaccine doi: 10.1016/j.vaccine.2019.07.044 – volume: 81 start-page: 1 year: 2016 ident: ref_121 article-title: Protective effect of two essential oils isolated from Rosa damascena Mill. and Lavandula angustifolia Mill, and two classic antioxidants against L-dopa oxidative toxicity induced in healthy mice publication-title: Regul. Toxicol. Pharmacol. doi: 10.1016/j.yrtph.2016.06.024 – volume: 7 start-page: 1398 year: 2017 ident: ref_24 article-title: Brain iron chelation by deferiprone in a phase 2 randomised double-blinded placebo controlled clinical trial in Parkinson’s disease publication-title: Sci. Rep. doi: 10.1038/s41598-017-01402-2 – volume: 54 start-page: 287 year: 2018 ident: ref_77 article-title: First line defence antioxidants-superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPX): Their fundamental role in the entire antioxidant defence grid publication-title: Alex. J. Med. – ident: ref_57 – volume: 86 start-page: 21 year: 2017 ident: ref_61 article-title: Protein Misfolding Diseases publication-title: Annu. Rev. Biochem. doi: 10.1146/annurev-biochem-061516-044518 – volume: 35 start-page: 1867 year: 2017 ident: ref_3 article-title: Concise Review: Mesenchymal Stem Cells in Neurodegenerative Diseases publication-title: Stem Cells doi: 10.1002/stem.2651 – volume: 9 start-page: 9 year: 2018 ident: ref_71 article-title: Chronic stress as a risk factor for Alzheimer’s disease: Roles of microglia-mediated synaptic remodeling, inflammation, and oxidative stress publication-title: Neurobiol. Stress doi: 10.1016/j.ynstr.2018.05.003
SSID	ssj0023259
Score	2.7274609
SecondaryResourceType	review_article
Snippet	Oxidative stress has been linked with a variety of diseases, being involved in the debut and/or progress of several neurodegenerative disorders. This review...
SourceID	pubmedcentral proquest pubmed crossref
SourceType	Open Access Repository Aggregation Database Index Database Enrichment Source
StartPage	5938
SubjectTerms	Alzheimer's disease Antioxidants Antioxidants - therapeutic use Cytochrome Cytotoxicity Dehydrogenases Dopamine Enzymes Humans Huntingtons disease Metabolism Mitochondria Neurodegenerative Diseases - pathology Neuroinflammatory Diseases Neurons Oxidation Oxidative stress Oxidative Stress - physiology Parkinson's disease Reactive Oxygen Species Review
Title	An Overview of Oxidative Stress, Neuroinflammation, and Neurodegenerative Diseases
URI	https://www.ncbi.nlm.nih.gov/pubmed/35682615 https://www.proquest.com/docview/2674367891 https://www.proquest.com/docview/2675610150 https://pubmed.ncbi.nlm.nih.gov/PMC9180653
Volume	23
WOSCitedRecordID	wos000808965900001&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D
hasFullText	1
inHoldings	1
isFullTextHit
isPrint
journalDatabaseRights	– providerCode: PRVPQU databaseName: Health & Medical Collection customDbUrl: eissn: 1422-0067 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0023259 issn: 1422-0067 databaseCode: 7X7 dateStart: 20000301 isFulltext: true titleUrlDefault: https://search.proquest.com/healthcomplete providerName: ProQuest – providerCode: PRVPQU databaseName: ProQuest Central customDbUrl: eissn: 1422-0067 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0023259 issn: 1422-0067 databaseCode: BENPR dateStart: 20000301 isFulltext: true titleUrlDefault: https://www.proquest.com/central providerName: ProQuest – providerCode: PRVPQU databaseName: ProQuest Research library customDbUrl: eissn: 1422-0067 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0023259 issn: 1422-0067 databaseCode: M2O dateStart: 20000301 isFulltext: true titleUrlDefault: https://search.proquest.com/pqrl providerName: ProQuest – providerCode: PRVPQU databaseName: Publicly Available Content Database customDbUrl: eissn: 1422-0067 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0023259 issn: 1422-0067 databaseCode: PIMPY dateStart: 20000301 isFulltext: true titleUrlDefault: http://search.proquest.com/publiccontent providerName: ProQuest
link	http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1Nb9QwEB3RLUhc-C4EShUkOFGrsR3H8QkVaAWH7q4KSMspcmIHFkG2NNsC_54ZJxu2ILhwieTYUSzPePxsz7wBeCx9hjBUKOaUS1iqcc6V0nKmZCoSp3WJj5BsQo_H-Wxmpv2BW9u7Va5sYjDUblHRGfmeIG95tKyGPzv5yihrFN2u9ik0NmCTmMrSEWw-PxhPj4ctlxQhXRrHVYhlymSd67vEjf7e_NOXVhDXjKHYlPVF6Q-k-bvD5NoKdHj9f_t-A6712DPe75TlJlzyzS240mWj_HEbjvebeHJOtsN_ixd1PPk-d4EWPH4TAkp248DkgSqJWtRFPO7GtnHda-c_BAbr8MHL7tqnvQPvDg_evnjF-pQLrEp1vmTWGG9Tx3nFha1cntROqzLltrYoO-LSR0QppeCl1sYlziE8KoU1uvZWIlyQWzBqFo2_B3GO2MxZR2Q_aCVqW1aCZ5VGRJmkqTV5BE9XY15UPR85pcX4XOC-hCRUrEsogidD65OOh-Mv7bZXIij62dgWv8Y_gkdDNc4juhyxjV-chTYEJREfR3C3k_bwI6ky3IVxFYG-oAdDA-LovljTzD8Grm7D6eZa3v93tx7AVUFhFYliQm3DaHl65h_C5ep8OW9Pd2BDz3R45ju9gmPpSEywNH19NH3_E_JyBVE
linkProvider	ProQuest
linkToHtml	http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMw1V1Lb9QwEB6VLQguvB-BAkaiJxo1tuM4PiBUUaqu2m5XUKT2FJzYgUWQLc22pX-K38jYebAFwa0HLjnETuJkHv4cz3wD8JzbBGEoE6ERJgpjiTaXc01DwWMWGSlzPPhiE3I0Svf31XgBfnS5MC6ssvOJ3lGbaeH-ka8yFy2PnlXRV4ffQlc1yu2udiU0GrXYsmenuGSrXw7XUb7LjG282Xu9GbZVBcIiluks1EpZHRtKC8p0YdKoNFLkMdWlxuE5ungETZwzmkupTGQMIoCcaSVLqznOiBzvewkWY1T2dACL4-HO-KBf4nHmy7NRnPXCRKikCbXnXEWrk89fa-a4bZTLhZmfBP9Atr8HaM7NeBs3_rdvdROut9iarDXGcAsWbHUbrjTVNs_uwNu1iuyeON9oT8m0JLvfJ8bTnpN3PmFmhXimEjQ5tJImo3OF6Mo0p4396Bm6_QXrzbZWfRfeX8gL3YNBNa3sAyApYk-jjSMzQi9Y6rxgNCkkIuYojrVKA3jRyTgrWr51V_bjS4brLqcR2bxGBLDc9z5seEb-0m-pE3nWeps6-yXvAJ71zegn3OaPruz02PdxUBnxfwD3G-3qH8RFgqtMKgKQ5_Su7-A4yM-3VJNPnotcUbczzx_-e1hP4erm3s52tj0cbT2Ca8ylkEQiZGIJBrOjY_sYLhcns0l99KQ1KAIfLlovfwJeNVzP
linkToPdf	http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMw1V1Lb9QwEB6V8hAX3o-UAkaiJ2ptbCdxfECoYllRFe1WPKTeghM77aI22zbblv41fh1j58EWBLceuOQQO4kTzzMz8w3AS2ETNEN5TE1sQhpJ5LlcaEZjEfHQSJnjwTebkONxurOjtpfgR1cL49IqO5noBbWZFe4f-YC7bHmUrIoNyjYtYns4enN4RF0HKRdp7dppNCSyZc_P0H2rX28Oca_XOB-9-_z2PW07DNAikumcaqWsjgxjBeO6MGlYGhnnEdOlxqU66Hg0oITgLJdSmdAYtAZyrpUsrRaoHQXe9wpclREqZZc2yCe9sye4b9TGUP_RJFZJk3QvhAoH028HNXcoN8pVxSyqwz9s3N9TNRd03-j2__zV7sCt1uImGw2L3IUlW92D600PzvP78HGjIpNTJzHtGZmVZPJ9ajwYOvnky2jWiccvQUZE3mnqPNeJrkxz2thdj9vtLxg2wa76AXy5lBd6CMvVrLKPgaRokRptHMQRysZS5wVnSSHRjg6jSKs0gFfdfmdFi8LumoHsZ-iNOerIFqkjgLV-9mGDPvKXeavd9metDKqzX3sfwIt-GKWHCwnpys5O_BxnQKNXEMCjhtL6B4k4Qd-TxQHICzTYT3DI5BdHqumeRyhXzMXrxcq_l_UcbiAxZh82x1tP4CZ3dSVhTHm8Csvz4xP7FK4Vp_NpffzMcxaBr5dNlD8BHOdkCQ
openUrl	ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=An+Overview+of+Oxidative+Stress%2C+Neuroinflammation%2C+and+Neurodegenerative+Diseases&rft.jtitle=International+journal+of+molecular+sciences&rft.au=Daniel+Mihai+Teleanu&rft.au=Niculescu%2C+Adelina-Gabriela&rft.au=Lungu%2C+Iulia+Ioana&rft.au=Radu%2C+Crina+Ioana&rft.date=2022-05-25&rft.pub=MDPI+AG&rft.issn=1661-6596&rft.eissn=1422-0067&rft.volume=23&rft.issue=11&rft.spage=5938&rft_id=info:doi/10.3390%2Fijms23115938&rft.externalDBID=HAS_PDF_LINK
thumbnail_l	http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1422-0067&client=summon
thumbnail_m	http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1422-0067&client=summon
thumbnail_s	http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1422-0067&client=summon