NRF2, a Transcription Factor for Stress Response and Beyond

Nuclear factor erythroid 2-related factor 2 (NRF2) is a transcription factor that regulates the cellular defense against toxic and oxidative insults through the expression of genes involved in oxidative stress response and drug detoxification. NRF2 activation renders cells resistant to chemical carc...

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Bibliographic Details
Published in:	International journal of molecular sciences Vol. 21; no. 13; p. 4777
Main Authors:	He, Feng, Ru, Xiaoli, Wen, Tao
Format:	Journal Article
Language:	English
Published:	Switzerland MDPI AG 06.07.2020 MDPI
Subjects:	Animals Autophagy Binding sites Breast cancer Endoplasmic reticulum Gene expression Gene Expression Regulation Humans Hydrocarbons Inflammation - physiopathology Kinases Metabolism NF-E2-Related Factor 2 - genetics NF-E2-Related Factor 2 - metabolism Oxidative Stress Phosphorylation Proteins Review Transcription factors Unfolded Protein Response transcription factor autophagy NRF2 inflammation UPR metabolism proteostasis oxidative stress
ISSN:	1422-0067, 1661-6596, 1422-0067
Online Access:	Get full text
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