Strategies to Improve the Efficiency of Somatic Cell Nuclear Transfer

Mammalian oocytes can reprogram differentiated somatic cells into a totipotent state through somatic cell nuclear transfer (SCNT), which is known as cloning. Although many mammalian species have been successfully cloned, the majority of cloned embryos failed to develop to term, resulting in the over...

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Bibliographic Details
Published in:	International journal of molecular sciences Vol. 23; no. 4; p. 1969
Main Authors:	Srirattana, Kanokwan, Kaneda, Masahiro, Parnpai, Rangsun
Format:	Journal Article
Language:	English
Published:	Switzerland MDPI AG 10.02.2022 MDPI
Subjects:	Animals Cattle Cellular Reprogramming - genetics Cellular Reprogramming - physiology Chromatin Chromosomes Cloning Cloning, Organism - methods Cytoplasm DNA methylation DNA Methylation - genetics DNA Methylation - physiology Efficiency Embryo, Mammalian - physiology Embryonic Development - genetics Embryonic Development - physiology Embryos Epigenesis, Genetic - genetics Epigenetics Gene expression Humans Light Mitochondrial DNA Nuclear Transfer Techniques Oocytes - physiology Review Sheep somatic cell nuclear transfer embryo epigenetic modification nuclear reprogramming cloning efficiency
ISSN:	1422-0067, 1661-6596, 1422-0067
Online Access:	Get full text
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