Pathophysiology of Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus (T2DM), one of the most common metabolic disorders, is caused by a combination of two primary factors: defective insulin secretion by pancreatic β-cells and the inability of insulin-sensitive tissues to respond appropriately to insulin. Because insulin release and activity a...

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Bibliographic Details
Published in:	International journal of molecular sciences Vol. 21; no. 17; p. 6275
Main Authors:	Galicia-Garcia, Unai, Benito-Vicente, Asier, Jebari, Shifa, Larrea-Sebal, Asier, Siddiqi, Haziq, Uribe, Kepa B., Ostolaza, Helena, Martín, César
Format:	Journal Article
Language:	English
Published:	Switzerland MDPI AG 30.08.2020 MDPI
Subjects:	Animals Blood Glucose - metabolism Cardiovascular disease Diabetes Diabetes Mellitus, Type 2 - physiopathology Epidemiology Ethnicity Family medical history Genomes Glucose Homeostasis Humans Hyperglycemia Inflammation Insulin resistance Insulin Secretion Lifestyles Metabolism Mortality Musculoskeletal system Obesity Pathogenesis Pathophysiology Physiology Population Review Risk factors cardiovascular disease liver adipocyte muscle pathophysiology type 2 diabetes mellitus β-cell insulin resistance
ISSN:	1422-0067, 1661-6596, 1422-0067
Online Access:	Get full text
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