Flow Cytometry-Based Characterization of Mast Cells in Human Atherosclerosis

The presence of mast cells in human atherosclerotic plaques has been associated with adverse cardiovascular events. Mast cell activation, through the classical antigen sensitized-IgE binding to their characteristic Fcε-receptor, causes the release of their cytoplasmic granules. These granules are fi...

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Veröffentlicht in:	Cells (Basel, Switzerland) Jg. 8; H. 4; S. 334
Hauptverfasser:	Kritikou, Eva, Depuydt, Marie A.C., de Vries, Margreet R., Mulder, Kevin E., Govaert, Arthur M., Smit, Marrit D., van Duijn, Janine, Foks, Amanda C., Wezel, Anouk, Smeets, Harm J., Slütter, Bram, Quax, Paul H.A., Kuiper, Johan, Bot, Ilze
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Switzerland MDPI AG 09.04.2019 MDPI
Schlagworte:	Arteriosclerosis Atherosclerosis Atherosclerosis - pathology CD63 antigen Cell activation Cells, Cultured Flow cytometry Flow Cytometry - methods Hemorrhage Histamine Histology Human subjects Humans Immunoglobulin E Immunoglobulin E - metabolism Immunohistochemistry Inflammation mast cell Mast cells Mast Cells - metabolism Mast Cells - pathology plaque stability Plaque, Atherosclerotic - pathology Plaques Population Proto-Oncogene Proteins c-kit - metabolism Receptors, IgE - metabolism Surgery Tetraspanin 30 - metabolism Tryptase Veins & arteries United States > US Netherlands atherosclerosis mast cell flow cytometry tryptase plaque stability
ISSN:	2073-4409, 2073-4409
Online-Zugang:	Volltext
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