Melatonin Effects on Non-Alcoholic Fatty Liver Disease Are Related to MicroRNA-34a-5p/Sirt1 Axis and Autophagy

Melatonin, an indole produced by pineal and extrapineal tissues, but also taken with a vegetarian diet, has strong anti-oxidant, anti-inflammatory and anti-obesogenic potentials. Non-alcoholic fatty liver disease (NAFLD) is the hepatic side of the metabolic syndrome. NAFLD is a still reversible phas...

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Bibliographic Details
Published in:	Cells (Basel, Switzerland) Vol. 8; no. 9; p. 1053
Main Authors:	Stacchiotti, Alessandra, Grossi, Ilaria, García-Gómez, Raquel, Patel, Gaurangkumar, Salvi, Alessandro, Lavazza, Antonio, De Petro, Giuseppina, Monsalve, Maria, Rezzani, Rita
Format:	Journal Article
Language:	English
Published:	Switzerland MDPI AG 08.09.2019 MDPI
Subjects:	Animals Autophagy Binding sites Biotechnology Calorimetry Carbohydrates Cirrhosis Diet Drinking behavior Fatty liver Gene expression Glucose Glucose tolerance High fat diet Histone deacetylase Indoles Inflammation Lipids Liver cirrhosis Liver diseases Melatonin Metabolic syndrome microRNA-34a-5p MicroRNAs miRNA Mitochondria Molecular modelling NAD nonalcoholic fatty liver disease Obesity Oxidants Phagocytosis Phagosomes Pineal gland Proteins Rodents SIRT1 SIRT1 protein Steatosis Sterol regulatory element-binding protein Vegetarian diet United States > US Italy nonalcoholic fatty liver disease melatonin SIRT1 microRNA-34a-5p obesity
ISSN:	2073-4409, 2073-4409
Online Access:	Get full text
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