Confocal Raman microspectroscopy on excised human skin: uncertainties in depth profiling and mathematical correction applied to dermatological drug permeation

Confocal Raman microspectroscopy represents the advantage of giving structural and conformational information on samples without any destructive treatment. Recently, several studies were achieved to study the skin hydration, endogenous and exogenous molecules repartition in the skin using the confoc...

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Bibliographic Details
Published in:	Journal of biophotonics Vol. 1; no. 2; pp. 140 - 153
Main Authors:	Tfayli, A., Piot, O., Manfait, M.
Format:	Journal Article
Language:	English
Published:	Berlin WILEY-VCH Verlag 01.05.2008 WILEY‐VCH Verlag
Subjects:	Anti-Infective Agents - administration & dosage Anti-Infective Agents - pharmacokinetics confocal Raman microspectroscopy depth correction Dermatologic Agents - pharmacokinetics Diffusion drug tracking human skin Humans In Vitro Techniques mathematical modeling Metronidazole - administration & dosage Metronidazole - pharmacokinetics Models, Biological Permeability Skin - metabolism Skin Absorption Spectrum Analysis, Raman - methods
ISSN:	1864-063X, 1864-0648, 1864-0648
Online Access:	Get full text
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