Immune targeting and host-protective effects of the latent stage of Toxoplasma gondii

Latency is a microbial strategy for persistence. For Toxoplasma gondii the bradyzoite stage forms long-lived cysts critical for transmission, and its presence in neurons is considered important for immune evasion. However, the extent to which cyst formation escapes immune pressure and mediates persi...

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Bibliographic Details
Published in:	Nature microbiology Vol. 10; no. 4; p. 992
Main Authors:	Eberhard, Julia N, Shallberg, Lindsey A, Winn, Aaron, Chandrasekaran, Sambamurthy, Giuliano, Christopher J, Merritt, Emily F, Willis, Elinor, Konradt, Christoph, Christian, David A, Aldridge, Daniel L, Bunkofske, Molly E, Jacquet, Maxime, Dzierszinski, Florence, Katifori, Eleni, Lourido, Sebastian, Koshy, Anita A, Hunter, Christopher A
Format:	Journal Article
Language:	English
Published:	England 01.04.2025
Subjects:	Animals CD8-Positive T-Lymphocytes - immunology Disease Models, Animal Host-Parasite Interactions - immunology Mice Mice, Inbred C57BL Models, Theoretical STAT1 Transcription Factor - immunology STAT1 Transcription Factor - metabolism Toxoplasma - growth & development Toxoplasma - immunology Toxoplasma - pathogenicity Toxoplasmosis - immunology Toxoplasmosis - parasitology Toxoplasmosis, Animal - immunology Toxoplasmosis, Animal - parasitology
ISSN:	2058-5276, 2058-5276
Online Access:	Get more information
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