Landscape of DNA methylation on the X chromosome reflects CpG density, functional chromatin state and X-chromosome inactivation

X-chromosome inactivation (XCI) achieves dosage compensation between males and females through the silencing of the majority of genes on one of the female X chromosomes. Thus, the female X chromosomes provide a unique opportunity to study euchromatin and heterochromatin of allelic regions within the...

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Vydané v:	Human molecular genetics Ročník 24; číslo 6; s. 1528
Hlavní autori:	Cotton, Allison M, Price, E Magda, Jones, Meaghan J, Balaton, Bradley P, Kobor, Michael S, Brown, Carolyn J
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	England 15.03.2015
Predmet:	Chromatin - metabolism Chromosomes, Human, X CpG Islands DNA Methylation DNA, Intergenic Female Gene Expression Regulation Humans Oligonucleotide Array Sequence Analysis Organ Specificity Promoter Regions, Genetic Transcription, Genetic X Chromosome Inactivation
ISSN:	1460-2083, 1460-2083
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