Hypoxia-Induced VISTA Promotes the Suppressive Function of Myeloid-Derived Suppressor Cells in the Tumor Microenvironment

Tumor hypoxia is a negative prognostic factor that is implicated in oncogenic signal activation, immune escape, and resistance to treatment. Identifying the mechanistic role of hypoxia in immune escape and resistance to immune-checkpoint inhibitors may aid the identification of therapeutic targets....

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Bibliographic Details
Published in:	Cancer immunology research Vol. 7; no. 7; p. 1079
Main Authors:	Deng, Jie, Li, Jiannan, Sarde, Aurelien, Lines, J Louise, Lee, Yu-Chi, Qian, David C, Pechenick, Dov A, Manivanh, Richard, Le Mercier, Isabelle, Lowrey, Christopher H, Varn, Frederick S, Cheng, Chao, Leib, David A, Noelle, Randolph J, Mabaera, Rodwell
Format:	Journal Article
Language:	English
Published:	United States 01.07.2019
ISSN:	2326-6074, 2326-6074
Online Access:	Get more information
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