The circRNA-mediated ceRNA molecular regulatory network in fatigue-type type 2 diabete

Fatigue is a common but poorly understood issue in type 2 diabetes (T2DM) that affects quality of life. Although ceRNA networks regulate disease progression, their role in T2DM-related fatigue (F-T2DM) is unclear. This study developed a circRNA-mediated ceRNA network to uncover the molecular interac...

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Bibliographic Details
Published in:	Journal of translational medicine Vol. 23; no. 1; pp. 973 - 16
Main Authors:	Zhen, Xian-Jie, Wu, Tao, Zhang, Min, Zhang, Chu-Yue, Liu, Rui-Jie, Jiang, Jing, Jiang, Guang-Jian
Format:	Journal Article
Language:	English
Published:	London BioMed Central 02.09.2025 BioMed Central Ltd BMC
Subjects:	Adult Aged Analysis Animals Anopheles Biomedical and Life Sciences Biomedicine Circular RNA Competing endogenous RNA Development and progression Dextrose Diabetes Mellitus, Experimental - complications Diabetes Mellitus, Experimental - genetics Diabetes Mellitus, Experimental - metabolism Diabetes Mellitus, Type 2 - complications Diabetes Mellitus, Type 2 - genetics Diabetes Mellitus, Type 2 - metabolism Energy Metabolism - genetics Fatigue Fatigue - genetics Fatigue - metabolism Female Gene Expression Profiling Gene Expression Regulation Gene Regulatory Networks Genes Glucose Humans Insulin - metabolism Male Medicine/Public Health Messenger RNA Mice Mice, Inbred C57BL Middle Aged Muscle proteins Nutrition & metabolism Physiological aspects RNA, Circular - metabolism RNA, Competitive Endogenous - metabolism RNA, Messenger - genetics RNA, Messenger - metabolism Signal Transduction - genetics Streptozocin - toxicity Type 2 diabetes Type 2 diabetes mellitus Circular RNA Fatigue Type 2 diabetes mellitus Competing endogenous RNA
ISSN:	1479-5876, 1479-5876
Online Access:	Get full text
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