TRIM8-associated non-coding RNA panel as a biomarker for Lupus nephritis activity

Background Lupus nephritis (LN) represents a major complication in systemic lupus erythematosus (SLE). The objective of this study was to evaluate the TRIM8 gene and its associated non-coding RNAs ( lnc-SSBP2-1:1 and hsa-miR-126-5p ) as potential non-invasive biomarkers for LN activity. Methods Bioi...

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Bibliographic Details
Published in:	Journal of translational medicine Vol. 23; no. 1; pp. 1229 - 10
Main Authors:	Elgawad, Mostafa Abdelnasier Abd, Shinnawy, Howayda Abdelhamid El, Eissa, Sanaa, Ali, Nouran Abdelfattah Sayed, Behairy, Maha Abdelmoneim, Kamel, Cherry Reda, Kamel, Marwa Mostafa
Format:	Journal Article
Language:	English
Published:	London BioMed Central 05.11.2025 BioMed Central Ltd BMC
Subjects:	Adult Analysis B cells Biological markers Biomarkers Biomarkers - blood Biomarkers - metabolism Biomedical and Life Sciences Biomedicine Care and treatment Carrier Proteins - genetics Carrier Proteins - metabolism Case-Control Studies Complications and side effects Development and progression Diagnosis Ethylenediaminetetraacetic acid Female hsa-miR-126-5p Humans Immune response Immunobiology and immunotherapy lnc-SSBP2-1:1 Lupus Lupus nephritis Lupus Nephritis - blood Lupus Nephritis - genetics Male Medicine/Public Health MicroRNAs - genetics MicroRNAs - metabolism Middle Aged Nephritis Nerve Tissue Proteins non-coding RNA network Polymerase chain reaction Risk factors RNA RNA, Long Noncoding - genetics RNA, Messenger - genetics RNA, Messenger - metabolism RNA, Untranslated - genetics RNA, Untranslated - metabolism Systemic lupus erythematosus Testing TRIM8 Tripartite Motif Proteins Egypt Biomarkers Disease activity Lupus nephritis non-coding RNA network TRIM8 hsa-miR-126-5p lnc-SSBP2-1:1
ISSN:	1479-5876, 1479-5876
Online Access:	Get full text
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