A Phase II Study of Fornix Deep Brain Stimulation in Mild Alzheimer's Disease

Deep brain stimulation (DBS) is used to modulate the activity of dysfunctional brain circuits. The safety and efficacy of DBS in dementia is unknown. To assess DBS of memory circuits as a treatment for patients with mild Alzheimer's disease (AD). We evaluated active "on" versus sham &...

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Veröffentlicht in:	Journal of Alzheimer's disease Jg. 54; H. 2; S. 777
Hauptverfasser:	Lozano, Andres M, Fosdick, Lisa, Chakravarty, M Mallar, Leoutsakos, Jeannie-Marie, Munro, Cynthia, Oh, Esther, Drake, Kristen E, Lyman, Christopher H, Rosenberg, Paul B, Anderson, William S, Tang-Wai, David F, Pendergrass, Jo Cara, Salloway, Stephen, Asaad, Wael F, Ponce, Francisco A, Burke, Anna, Sabbagh, Marwan, Wolk, David A, Baltuch, Gordon, Okun, Michael S, Foote, Kelly D, McAndrews, Mary Pat, Giacobbe, Peter, Targum, Steven D, Lyketsos, Constantine G, Smith, Gwenn S
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Netherlands 06.09.2016
Schlagworte:	Aged Alzheimer Disease - diagnostic imaging Alzheimer Disease - metabolism Alzheimer Disease - therapy Deep Brain Stimulation - methods Double-Blind Method Female Fornix, Brain - diagnostic imaging Fornix, Brain - metabolism Glucose - metabolism Humans Male Middle Aged Pilot Projects Positron-Emission Tomography - methods dementia fornix Keywords: Alzheimer’s disease deep brain stimulation
ISSN:	1875-8908, 1875-8908
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