Covalent Organic Frameworks (COFs) for Cancer Therapeutics

As newly emerged crystalline porous materials, covalent organic frameworks (COFs) possess fascinating structures and some specific features such as modularity, crystallinity, porosity, stability, versatility, and biocompatibility. Besides adsorption/separation, sensing, catalysis, and energy applica...

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Veröffentlicht in:Chemistry : a European journal Jg. 26; H. 25; S. 5583 - 5591
Hauptverfasser: Guan, Qun, Zhou, Le‐Le, Li, Wen‐Yan, Li, Yan‐An, Dong, Yu‐Bin
Format: Journal Article
Sprache:Englisch
Veröffentlicht: Germany Wiley Subscription Services, Inc 04.05.2020
Schlagworte:
Biocompatibility
Biomedical materials
Cancer
Catalysis
Chemistry
covalent organic frameworks
Crystal structure
Crystallinity
Drug delivery
Drug delivery systems
Modularity
nanomaterials
Photodynamic therapy
phototherapy
Porosity
Porous materials
covalent organic frameworks
cancer
nanomaterials
phototherapy
drug delivery
ISSN:0947-6539, 1521-3765, 1521-3765
Online-Zugang:Volltext
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Zusammenfassung:As newly emerged crystalline porous materials, covalent organic frameworks (COFs) possess fascinating structures and some specific features such as modularity, crystallinity, porosity, stability, versatility, and biocompatibility. Besides adsorption/separation, sensing, catalysis, and energy applications, COFs have recently shown a promise in biomedical applications. This contribution provides an overview of the recent developments of COF‐based medicines in cancer therapeutics, including drug delivery, photodynamic therapy (PDT), photothermal therapy (PTT), and combined therapy. Furthermore, the major challenges and developing trends in this field are also discussed. These recent developments are summarized and discussed to help encourage further contributions in this emerging and promising field. Magic bullet: In this minireview, recent advances in the field of covalent organic frameworks (COFs) for cancer therapeutic applications are highlighted, including those for drug delivery, phototherapy, and combined therapy.
Bibliographie:These authors equally contributed to this work.
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ISSN:0947-6539
1521-3765
1521-3765
DOI:10.1002/chem.201905150