The prediabetes conundrum: striking the balance between risk and resources

The current definition of prediabetes is controversial and subject to continuous debate. Nonetheless, prediabetes is a risk factor for type 2 diabetes, is highly prevalent and is associated with diabetic complications and mortality. Thereby, it has the potential to become a huge strain on healthcare...

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Bibliographic Details
Published in:Diabetologia Vol. 66; no. 6; pp. 1016 - 1023
Main Authors: Blond, Martin B., Færch, Kristine, Herder, Christian, Ziegler, Dan, Stehouwer, Coen D. A.
Format: Journal Article
Language:English
Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.06.2023
Springer Nature B.V
Subjects:
Diabetes
Diabetes Complications - complications
Diabetes mellitus (non-insulin dependent)
Diabetes Mellitus, Type 2 - complications
Disease prevention
For Debate
Health care
Health risks
Human Physiology
Humans
Hyperglycemia
Internal Medicine
Medicine
Medicine & Public Health
Metabolic Diseases
Metabolic syndrome
Prediabetic State - complications
Risk Factors
Risk
Stratified medicine
Intermediate hyperglycaemia
Prediabetes
ISSN:0012-186X, 1432-0428, 1432-0428
Online Access:Get full text
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Summary:The current definition of prediabetes is controversial and subject to continuous debate. Nonetheless, prediabetes is a risk factor for type 2 diabetes, is highly prevalent and is associated with diabetic complications and mortality. Thereby, it has the potential to become a huge strain on healthcare systems in the future, necessitating action from legislators and healthcare providers. But how do we best reduce its associated burden on health? As a compromise between differing opinions in the literature and among the authors of this article, we suggest stratifying individuals with prediabetes according to estimated risk and only offering individual-level preventive interventions to those at high risk. At the same time, we argue to identify those with prediabetes and already established diabetes-related complications and treat them as we would treat individuals with established type 2 diabetes. Graphical abstract
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ISSN:0012-186X
1432-0428
1432-0428
DOI:10.1007/s00125-023-05890-y