The prediabetes conundrum: striking the balance between risk and resources

The current definition of prediabetes is controversial and subject to continuous debate. Nonetheless, prediabetes is a risk factor for type 2 diabetes, is highly prevalent and is associated with diabetic complications and mortality. Thereby, it has the potential to become a huge strain on healthcare...

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Vydáno v:	Diabetologia Ročník 66; číslo 6; s. 1016 - 1023
Hlavní autoři:	Blond, Martin B., Færch, Kristine, Herder, Christian, Ziegler, Dan, Stehouwer, Coen D. A.
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	Berlin/Heidelberg Springer Berlin Heidelberg 01.06.2023 Springer Nature B.V
Témata:	Diabetes Diabetes Complications - complications Diabetes mellitus (non-insulin dependent) Diabetes Mellitus, Type 2 - complications Disease prevention For Debate Health care Health risks Human Physiology Humans Hyperglycemia Internal Medicine Medicine Medicine & Public Health Metabolic Diseases Metabolic syndrome Prediabetic State - complications Risk Factors Risk Stratified medicine Intermediate hyperglycaemia Prediabetes
ISSN:	0012-186X, 1432-0428, 1432-0428
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Abstract	The current definition of prediabetes is controversial and subject to continuous debate. Nonetheless, prediabetes is a risk factor for type 2 diabetes, is highly prevalent and is associated with diabetic complications and mortality. Thereby, it has the potential to become a huge strain on healthcare systems in the future, necessitating action from legislators and healthcare providers. But how do we best reduce its associated burden on health? As a compromise between differing opinions in the literature and among the authors of this article, we suggest stratifying individuals with prediabetes according to estimated risk and only offering individual-level preventive interventions to those at high risk. At the same time, we argue to identify those with prediabetes and already established diabetes-related complications and treat them as we would treat individuals with established type 2 diabetes. Graphical abstract
AbstractList	The current definition of prediabetes is controversial and subject to continuous debate. Nonetheless, prediabetes is a risk factor for type 2 diabetes, is highly prevalent and is associated with diabetic complications and mortality. Thereby, it has the potential to become a huge strain on healthcare systems in the future, necessitating action from legislators and healthcare providers. But how do we best reduce its associated burden on health? As a compromise between differing opinions in the literature and among the authors of this article, we suggest stratifying individuals with prediabetes according to estimated risk and only offering individual-level preventive interventions to those at high risk. At the same time, we argue to identify those with prediabetes and already established diabetes-related complications and treat them as we would treat individuals with established type 2 diabetes. Graphical abstract The current definition of prediabetes is controversial and subject to continuous debate. Nonetheless, prediabetes is a risk factor for type 2 diabetes, is highly prevalent and is associated with diabetic complications and mortality. Thereby, it has the potential to become a huge strain on healthcare systems in the future, necessitating action from legislators and healthcare providers. But how do we best reduce its associated burden on health? As a compromise between differing opinions in the literature and among the authors of this article, we suggest stratifying individuals with prediabetes according to estimated risk and only offering individual-level preventive interventions to those at high risk. At the same time, we argue to identify those with prediabetes and already established diabetes-related complications and treat them as we would treat individuals with established type 2 diabetes. The current definition of prediabetes is controversial and subject to continuous debate. Nonetheless, prediabetes is a risk factor for type 2 diabetes, is highly prevalent and is associated with diabetic complications and mortality. Thereby, it has the potential to become a huge strain on healthcare systems in the future, necessitating action from legislators and healthcare providers. But how do we best reduce its associated burden on health? As a compromise between differing opinions in the literature and among the authors of this article, we suggest stratifying individuals with prediabetes according to estimated risk and only offering individual-level preventive interventions to those at high risk. At the same time, we argue to identify those with prediabetes and already established diabetes-related complications and treat them as we would treat individuals with established type 2 diabetes.The current definition of prediabetes is controversial and subject to continuous debate. Nonetheless, prediabetes is a risk factor for type 2 diabetes, is highly prevalent and is associated with diabetic complications and mortality. Thereby, it has the potential to become a huge strain on healthcare systems in the future, necessitating action from legislators and healthcare providers. But how do we best reduce its associated burden on health? As a compromise between differing opinions in the literature and among the authors of this article, we suggest stratifying individuals with prediabetes according to estimated risk and only offering individual-level preventive interventions to those at high risk. At the same time, we argue to identify those with prediabetes and already established diabetes-related complications and treat them as we would treat individuals with established type 2 diabetes.
Author	Ziegler, Dan Færch, Kristine Blond, Martin B. Herder, Christian Stehouwer, Coen D. A.
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Keywords	Risk Stratified medicine Intermediate hyperglycaemia Prediabetes
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Snippet	The current definition of prediabetes is controversial and subject to continuous debate. Nonetheless, prediabetes is a risk factor for type 2 diabetes, is...
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SubjectTerms	Diabetes Diabetes Complications - complications Diabetes mellitus (non-insulin dependent) Diabetes Mellitus, Type 2 - complications Disease prevention For Debate Health care Health risks Human Physiology Humans Hyperglycemia Internal Medicine Medicine Medicine & Public Health Metabolic Diseases Metabolic syndrome Prediabetic State - complications Risk Factors
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Title	The prediabetes conundrum: striking the balance between risk and resources
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