The many facets of hyperhomocysteinemia: studies from the Framingham cohorts

Homocysteine is a sulfur amino acid whose metabolism stands at the intersection of 2 pathways: remethylation, which requires folic acid and B-12 coenzymes, and transsulfuration, which requires pyridoxal-5'-phosphate, the B-6 coenzyme. Data from several studies suggest that mild elevations of ho...

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Bibliographic Details
Published in:	The Journal of nutrition Vol. 136; no. 6 Suppl; p. 1726S
Main Author:	Selhub, Jacob
Format:	Journal Article
Language:	English
Published:	United States 01.06.2006
Subjects:	Aged Aged, 80 and over Alzheimer Disease - epidemiology Cardiovascular Diseases - epidemiology Cardiovascular Diseases - mortality Carotid Stenosis - etiology Cohort Studies Dementia - epidemiology Diet Female Folic Acid - administration & dosage Folic Acid - blood Fractures, Bone Heart Failure - epidemiology Homocysteine - blood Humans Hyperhomocysteinemia - complications Male Massachusetts Middle Aged Risk Factors Stroke - epidemiology Vascular Diseases - etiology Vitamin B 12 - administration & dosage Vitamin B 12 - blood Vitamin B 6 - administration & dosage Vitamin B 6 - blood Massachusetts
ISSN:	0022-3166
Online Access:	Get more information
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