UBTF tandem duplications in pediatric myelodysplastic syndrome and acute myeloid leukemia: implications for clinical screening and diagnosis

Recent genomic studies in adult and pediatric acute myeloid leukemia (AML) demonstrated recurrent in-frame tandem duplications (TD) in exon 13 of upstream binding transcription factor (UBTF). These alterations, which account for ~4.3% of AMLs in childhood and about 3% in adult AMLs under 60, are sub...

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Bibliographic Details

Published in:	Haematologica (Roma) Vol. 109; no. 8; pp. 2459 - 2468
Main Authors:	Barajas, Juan M., Umeda, Masayuki, Contreras, Lisett, Khanlari, Mahsa, Westover, Tamara, Walsh, Michael P., Xiong, Emily, Yang, Chenchen, Otero, Brittney, Arribas-Layton, Marc, Abdelhamed, Sherif, Song, Guangchun, Ma, Xiaotu, Thomas 3rd, Melvin E., Ma, Jing, Klco, Jeffery M.
Format:	Journal Article
Language:	English
Published:	Italy Fondazione Ferrata Storti 01.08.2024 Ferrata Storti Foundation
Subjects:	Acute Myeloid Leukemia
ISSN:	0390-6078, 1592-8721, 1592-8721
Online Access:	Get full text
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