First-generation clinical dual-source photon-counting CT: ultra-low-dose quantitative spectral imaging

Objective Evaluation of image characteristics at ultra-low radiation dose levels of a first-generation dual-source photon-counting computed tomography (PCCT) compared to a dual-source dual-energy CT (DECT) scanner. Methods A multi-energy CT phantom was imaged with and without an extension ring on bo...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:European radiology Ročník 32; číslo 12; s. 8579 - 8587
Hlavní autoři: Liu, Leening P., Shapira, Nadav, Chen, Andrew A., Shinohara, Russell T., Sahbaee, Pooyan, Schnall, Mitchell, Litt, Harold I., Noël, Peter B.
Médium: Journal Article
Jazyk:angličtina
Vydáno: Berlin/Heidelberg Springer Berlin Heidelberg 01.12.2022
Springer Nature B.V
Témata:
Background noise
Computed Tomography
Diagnostic Radiology
Exposure
Humans
Imaging
Inserts
Internal Medicine
Interventional Radiology
Medical diagnosis
Medical imaging
Medicine
Medicine & Public Health
Neuroradiology
Noise reduction
Phantoms, Imaging
Photons
Radiation
Radiation Dosage
Radiation effects
Radiology
Scanners
Tomography, X-Ray Computed - methods
Ultrasound
X-ray computed tomography
Diagnostic imaging
Radiation dosage
ISSN:1432-1084, 0938-7994, 1432-1084
On-line přístup:Získat plný text
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!
Popis
Shrnutí:Objective Evaluation of image characteristics at ultra-low radiation dose levels of a first-generation dual-source photon-counting computed tomography (PCCT) compared to a dual-source dual-energy CT (DECT) scanner. Methods A multi-energy CT phantom was imaged with and without an extension ring on both scanners over a range of radiation dose levels (CTDI vol 0.4–15.0 mGy). Scans were performed in different modes of acquisition for PCCT with 120 kVp and DECT with 70/Sn150 kVp and 100/Sn150 kVp. Various tissue inserts were used to characterize the precision and repeatability of Hounsfield units (HUs) on virtual mono-energetic images between 40 and 190 keV. Image noise was additionally investigated at an ultra-low radiation dose to illustrate PCCT’s ability to remove electronic background noise. Results Our results demonstrate the high precision of HU measurements for a wide range of inserts and radiation exposure levels with PCCT. We report high performance for both scanners across a wide range of radiation exposure levels, with PCCT outperforming at low exposures compared to DECT. PCCT scans at the lowest radiation exposures illustrate significant reduction in electronic background noise, with a mean percent reduction of 74% ( p value ~ 10 −8 ) compared to DECT 70/Sn150 kVp and 60% ( p value ~ 10 −6 ) compared to DECT 100/Sn150 kVp. Conclusions This paper reports the first experiences with a clinical dual-source PCCT. PCCT provides reliable HUs without disruption from electronic background noise for a wide range of dose values. Diagnostic benefits are not only for quantification at an ultra-low dose but also for imaging of obese patients. Key Points PCCT scanners provide precise and reliable Hounsfield units at ultra-low dose levels. The influence of electronic background noise can be removed at ultra-low-dose acquisitions with PCCT. Both spectral platforms have high performance along a wide range of radiation exposure levels, with PCCT outperforming at low radiation exposures.
Bibliografie:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 14
content type line 23
ISSN:1432-1084
0938-7994
1432-1084
DOI:10.1007/s00330-022-08933-x