Cuproptosis: p53-regulated metabolic cell death?

Cuproptosis is a novel type of copper-induced cell death that primarily occurs in cells that utilize oxidative phosphorylation as the main metabolic pathway to produce energy. Copper directly associates with the lipoylated proteins of the tricarboxylic acid cycle, leading to the disulfide-bond-depen...

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Vydané v:	Cell death and differentiation Ročník 30; číslo 4; s. 876 - 884
Hlavní autori:	Xiong, Chen, Ling, Hong, Hao, Qian, Zhou, Xiang
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	England Nature Publishing Group 01.04.2023
Predmet:	Apoptosis Cell death Copper Copper - metabolism Glutathione Glycolysis Iron Iron - metabolism Metabolic pathways Metabolism Metabolites Mutants Oxidative Phosphorylation p53 Protein Phosphorylation Proteins Sulfur Tricarboxylic acid cycle Tumor suppressor genes Tumor Suppressor Protein p53 - genetics Tumor Suppressor Protein p53 - metabolism Tumors
ISSN:	1350-9047, 1476-5403, 1476-5403
On-line prístup:	Získať plný text
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