Implications of obesity and insulin resistance for the treatment of oestrogen receptor-positive breast cancer

Breast cancer is the most common cancer in women, and incidence rates are rising, it is thought in part, due to increasing levels of obesity. Endocrine therapy (ET) remains the cornerstone of systemic therapy for early and advanced oestrogen receptor-positive (ER + ) breast cancer, but despite treat...

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Bibliographic Details
Published in:	British journal of cancer Vol. 131; no. 11; pp. 1724 - 1736
Main Authors:	Javed, Sohail Rooman, Skolariki, Aglaia, Zameer, Mohammed Zeeshan, Lord, Simon R
Format:	Journal Article
Language:	English
Published:	England Nature Publishing Group 14.12.2024
Subjects:	Antineoplastic Agents, Hormonal - adverse effects Antineoplastic Agents, Hormonal - therapeutic use Body mass index Breast cancer Breast Neoplasms - drug therapy Breast Neoplasms - metabolism Cancer therapies Clinical outcomes Diabetes mellitus Drug Resistance, Neoplasm Endocrine therapy Estrogen receptors Female Humans Insulin Resistance Obesity Obesity - complications Obesity - metabolism Receptors, Estrogen - metabolism Toxicity Womens health
ISSN:	0007-0920, 1532-1827, 1532-1827
Online Access:	Get full text
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